Clinical trials: Patient Controlled Analgesia
Postoperative Pain
Role of Dexamethasone for Erector Spinae Plane Block in Patients Undergoing Total Abdominal Hysterectomy
The aim to study the efficacy of bupivacaine 0.25% with dexamethasone and that of bupivacaine 0.25% alone for erector spinae plane block for postoperative analgesia in patients undergoing total abdominal hysterectomy Group 1…
- Trial name
- NCT03769818
- Testing
- bupivacaine, dexamethasone
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
Organ Dysfunction, Organ Support
Thoracic Epidural Analgesia for Acute Pancreatitis With Early Organ Dysfunction
Acute pancreatitis may cause early respiratory, cardiovascular, or renal dysfunction and may require intensive care and organ support.
- Conditions
- Organ Dysfunction, Organ Support, Acute Pancreatitis (AP)
- Trial name
- TEA-APOD (NCT07697690)
- Testing
- Thoracic Epidural Analgesia With Ropivacaine, conventional analgesia
- Volunteers
- 150 people
- Sponsor
- First People's Hospital of Chenzhou
Propofol, Sevoflurane
Comparison of Sevoflurane and Propofol on ANI
The goal of this clinical trial is to compare the effect of sevoflurane and propofol on analgesia nociception index(ANI) in patients undergoing general anesthesia.
- Conditions
- Propofol, Sevoflurane, Analgesia Nociception Index
- Trial name
- NCT06907823
- Testing
- propofol, Sevoflurane
- Volunteers
- 30 people
- Sponsor
- Pusan National University Yangsan Hospital
Femoral Neck Fractures, Femur Head Necrosis
Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG)
The goal of this clinical trial is to study the analgesic effect of liposomal bupivacaine plus bupivacaine for Pericapsular Nerve Group (PENG) block in postoperative pain management following hip replacement surgery.
- Conditions
- Femoral Neck Fractures, Femur Head Necrosis, Hip Fractures
- Trial name
- PENG (NCT06565910)
- Testing
- Liposomal bupivacaine plus bupivacaine, Ropivacaine
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Huazhong University of Science and Technology
Chronic Kidney Diseases, Pain, Procedural
Effect of 4-7-8 Breathing on AV Fistula Needle Pain in Dialysis Patients
For many hemodialysis patients, needle insertion into the vascular access site (fistula) is a significant source of pain and anxiety.
- Conditions
- Chronic Kidney Diseases, Pain, Procedural, Arteriovenous Fistula
- Trial name
- NCT07700680
- Testing
- Breathing technique
- Volunteers
- 80 people
- Sponsor
- Izmir Kavram Vocational School
Provide Post Hepatectomy Pain Control
Bilateral External Oblique Intercostal Plane Block in Post Operative Pain Management in Hepatectomy
The majority of cases undergoing hepatectomy suffer from inadequate postoperative analgesia. Therefore, multimodal analgesic techniques are required to relieve pain and discomfort such as intravenous, and epidural analgesia, and…
- Trial name
- EOI (NCT06822309)
- Testing
- External Oblique Intercostal Plane Block, Patient controlled analgesia
- Volunteers
- 40 people
- Sponsor
- Sherif Alaa Embaby
Labor Pain, Full Term Pregnancy
Patient Controlled Remifentanil Analgesia for Normal Labour
Patient controlled remifentanil analgesia might offer comparative overall patient satisfaction and improved quality of analgesia after normal labour with continuous epidural analgesia.
- Trial name
- NCT04541719
- Testing
- Patient-controlled remifentanil analgesia, Epidural analgesia
- Where
- Egypt
- Sponsor
- Mansoura University
Low Back Pain
Assessment of Acupuncture to Improve Function, Exercise Capacity, and Pain
The purpose of this research proposal is to conduct a feasibility study to determine the viability a larger efficacy study of combined acupuncture treatments plus treadmill exercise to decrease pain, facilitate exercise, and…
- Trial name
- NCT00502619
- Testing
- Acupuncture, Treadmill Exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA Maryland Health Care System
Cerebral Palsy, Hip Dysplasia
Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT04074265
- Testing
- Ropivacaine injection, normal saline
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of California, Los Angeles
Healthy, Hyperalgesia
Positron Emission Tomography to Measure Pain and Pain Control
This study will examine how the brain processes pain signals and how the different parts of the brain work with each other in response to painful stimuli.
- Conditions
- Healthy, Hyperalgesia, Pain, Peripheral Nervous System Disease
- Trial name
- NCT00001307
- Testing
- Oxygen-15 Water, Capsaicin
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Postoperative Pain Management, Cholecystectomy, Laparoscopic
Analgesic Efficacy of Bupivacaine Infiltration, Erector Spinae Plane Block, and Intrathecal Morphine in Laparoscopic Cholecystectomy
This study is designed to compare three different methods of pain control after laparoscopic gallbladder surgery (laparoscopic cholecystectomy).
- Trial name
- ITM-ESP-IPLA (NCT07203794)
- Testing
- Bupivacaine Infiltration, Erector Spinae Plane Block, Intrathecal Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Ataturk University
Low Back Pain, Chronic Pain (Back / Neck)
Digitally Delivered Treatments to Reduce Chronic Low Back Pain
This study aims to evaluate the effectiveness of pain education and clinical hypnosis delivered via a mobile app compared to a guideline-informed factsheet for reducing pain and disability in people experiencing chronic low back…
- Conditions
- Low Back Pain, Chronic Pain (Back / Neck), General Practice (GP), Primary Care Settings, Digital Health
- Trial name
- NOTUS (NCT06984354)
- Testing
- Pain education and clinical hypnosis delivered via a mobile app, Guideline-informed factsheet
- Where
- Australia
- Volunteers
- 720 people
- Sponsor
- Neuroscience Research Australia
Postoperative Pain, Hysterectomy
Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After Hysterectomy
Intravenous patient-controlled analgesia (PCA) is a popular technique for postoperative pain management. Although several drugs are recognized as effective therapeutic options, optimal selection of drugs in hysterectomy patients…
- Trial name
- BATPCAH (NCT00510666)
- Testing
- Saline, Butorphanol tartrate, Tramadol Hydrochloride
- Where
- China
- Volunteers
- 841 people
- Sponsor
- Nanjing Medical University
Anesthesia, Regional Anesthesia
Laparoscopic Sleeve Gastrectomy Surgery and External Oblique Intercostal Block
In obese patients, adequate pain relief in the postoperative period is an important parameter that affects patient comfort and hospital stay.
- Conditions
- Anesthesia, Regional Anesthesia, Morbid Obesity, Postoperative Pain
- Trial name
- NCT05822479
- Testing
- Bilateral ultrasound guided external oblique intercostal block (EOIB), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Right Lobe Hepatectomy
Continuous Paravertebral Block on Postoperative Pain After Hepatectomy
Patients often experience moderate to severe postoperative pain, especially during the first hours after hepatectomy. Systemic opioids given with patient-controlled analgesia has be used after hepatectomy in many medical…
- Trial name
- NCT01691937
- Testing
- Continuous Paravertebral block with ropivacaine, Patient-controlled analgesia with sufentanil, Continuous Paravertebral Block with Saline
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Huazhong University of Science and Technology
Pain, Pain Control
Postoperative Pain Reported to Nurses and Physicians
Effective pain control following surgical procedures is a goal for both the patient as well as the medical staff caring for them.
- Conditions
- Pain, Pain Control, Postoperative Pain
- Trial name
- NCT03840356
- Testing
- Postoperative
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Postoperative Pain Management After Total Hip Arthroplasty
Treatment of Postoperative Pain After Total Hip Arthroplasty Using Intravenous Lidocaine Infusion
This study will focus on patients undergoing total hip arthroplasty and Loma Linda University Medical Center \& East Campus. These patients will be randomized to receive a low dose lidocaine infusion or placebo, in addition to…
- Trial name
- NCT01108562
- Testing
- Lidocaine, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Aortic Valve Stenosis
Analgesia in Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation (TF-TAVI)
Ilioinguinal and iliohypogastric (ILIH) nerve blocks are frequently performed for analgesia in inguinal surgery. The investigators hypothesized that preoperative ultrasound-guided ilioinguinal and iliohypogastric (ILIH) nerve…
- Trial name
- TF-TAVI (NCT03863899)
- Testing
- Nerve block, Local infiltration, TAVI
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Gdansk
Epidural Anesthesia, Cesarean Section
A Comparison of Different Concentration Ropivacaine for Patient-controlled Epidural Analgesia
To compare the postoperative analgesic effect and the intensity of motor block in different concentration ropivacaine plus fentanyl when used epidurally with a patient-controlled analgesia device after Cesarean delivery.
- Trial name
- PCEA (NCT03195309)
- Testing
- Ropivacaine, Fentanyl
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Analgesia
Analgesic Efficacy of Continuous Infusion of Local Anaesthetic Versus Single-shot Injection Interscalene Block
The aim of this study is to study the analgesic efficacy of a continuous infusion of local anaesthetics for interscalene brachial plexus block after major shoulder surgery in the setting of multimodal analgesia, in order to…
- Trial name
- BIGKIS (NCT04394130)
- Testing
- ropivacaine 0.2%
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Eric Albrecht