Clinical trials: Patient Comprehension
Stage IV Melanoma
Investigating Participation Patterns Among Stage IV Melanoma Patients
Clinical trials, specifically focused on stage IV melanoma, are crucial in assessing the safety and efficacy of new treatments for this disease.
- Trial name
- NCT06093594
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Diabetes Mellitus, Type 2
O-SEMA-Fast: A Research Study to Understand How Oral Semaglutide Works in People With Type 2 Diabetes Who Plan to Fast During Ramadan in the United Arab Emirates, Saudi Arabia, and Kuwait
The purpose of the study is to look at the change in blood sugar levels in people with type 2 diabetes who are using oral semaglutide and planning to fast during Ramadan.
- Trial name
- O-SEMA-Fast (NCT05716724)
- Testing
- Semaglutide
- Where
- 20 sites in Kuwait, Saudi Arabia and 1 more
- Volunteers
- 288 people
- Sponsor
- Novo Nordisk A/S
Lung Cancer, Blood Relatives of Patient w/Lung Cancer
Effect of Lung Cancer Diagnoses on Family Behaviors
Background: A health event can be a powerful motivator for abrupt behavior changes. For instance, many people who smoke stop after having a heart attack or being diagnosed with cancer.
- Conditions
- Lung Cancer, Blood Relatives of Patient w/Lung Cancer, Cigarette Smokers
- Trial name
- NCT01862770
- Where
- 2 sites in United States
- Volunteers
- 507 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Chondrosarcoma
Understanding Engagement Trends in Chondrosarcoma Clinical Trials
Taking part in medical research usually favors a particular demographic group. But there is limited research available to explain what trial attributes affect the completion of these specific demographic groups.
- Trial name
- NCT06029478
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
The Effect of Audio-visual Aids on Bowel Cleanliness, Audiovisual Aids
Visual Aids for Colonoscopy Preparation: A Prospective Study on Patient Understanding and Bowel Cleanliness in Colonoscopy Patients
Effective communication in healthcare is critical for improving patient outcomes, particularly in enhancing health literacy and enabling informed decision-making.
- Trial name
- VACP (NCT07155603)
- Testing
- Animated Video Group 1
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Prof. Dr. Jörg Leuppi
Generalized Arterial Calcification in Infancy, Autosomal Recessive Hypophosphatemic Rickets Type 2
Understanding the Spectrum of ENPP1 Deficiency and Acute ABCC6 Deficiency
To date, the investigators lack characterization of, the burden of, and the systemic progression of disease in ENPP1 deficiency and ABCC6 deficiency from a patient and/or parent perspective.
- Trial name
- NCT04372446
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Inozyme Pharma
Epilepsy
Trobalt™ Products Risk Survey
As part of a European post-marketing commitment, GSK will conduct a survey of physicians' and patients' understanding of the significant risks associated with Trobalt™ (retigabine), as described in the Patient Information Leaflet…
- Trial name
- NCT01721213
- Testing
- Trobalt™
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI), Anxiety
Educational Video to Improve Understanding and Reduce Anxiety in Heart Attack Patients
Patients who are diagnosed with a heart attack are often confronted with an unexpected hospital admission and an urgent heart catheterization.
- Conditions
- Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI), Anxiety, Patient Education Materials
- Trial name
- VID-ACS (NCT07424482)
- Testing
- Educational Video
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Tobias Schreiber
Rheumatoid Arthritis
A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis
The purpose of this study is to learn how different types of medicines may improve disease activity in people with rheumatoid arthritis (RA). RA is a kind of joint disease that causes pain and swelling.
- Trial name
- NCT06418529
- Testing
- tofacitinib, tumor necrosis factor inhibitors (TNFi), abatacept
- Where
- United States
- Volunteers
- 21,340 people
- Sponsor
- Pfizer
Aphasia
Effect of Music on Reading Comprehension for Patients With Aphasia
This investigation uses a single-subject, adapted alternating research design to compare two different experimental conditions using music with lyrics combined with visual stimulation of the written lyrics, to extend the…
- Trial name
- EMRA1 (NCT02875938)
- Testing
- Simultaneous music and reading lyrics, Priming with music, Control
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Carilion Clinic
Telemedicine, Inflammatory Bowel Diseases
A Qualitative Study on Patients' (un)Ability and (un)Willingness to Use Telemonitoring in Inflammatory Bowel Diseases
Crohn's disease and ulcerative colitis (inflammatory bowel disease, IBD) are chronic intestinal inflammations with considerable impact on quality of life.
- Conditions
- Telemedicine, Inflammatory Bowel Diseases, Disparity, Health Equity
- Trial name
- NCT06123052
- Testing
- Interview
- Where
- 2 sites in Netherlands
- Volunteers
- 18 people
- Sponsor
- Franciscus Gasthuis
Breast Cancer, Colon Cancer
Understanding Patient Perspectives on the Risks of Ionizing Radiation Used for Medical Imaging
Risks from imaging-related radiation exposure have become a popular topic in the media. Because these tests are commonly applied to patients at a cancer center, it is important to understand what patients know, how they feel…
- Conditions
- Breast Cancer, Colon Cancer, Lung Cancer, Neuroblastoma
- Trial name
- NCT01482741
- Testing
- Focus Group Sessions
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Heart Failure With Reduced Ejection Fraction
Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score
The purpose of this trial is to better understand how the beta-blocker metoprolol works in people with Heart Failure with Reduced Ejection Fraction (HFrEF) according to participants genetics.
- Trial name
- NCT07490067
- Testing
- Metoprolol Succinate, Beta-Blocker Polygenic Score, Illumina Infinium Global Diversity Array with Enhanced Pharmacogenomics (PGx)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Metastatic Castration Resistant Prostate Cancer
Personalizing Enzalutamide Therapy by Understanding the Relation Between Tumor mRNAs, miRNAs and Treatment Response
The primary aim is to show whether a reduction in tumor related mRNAs and a panel of selected miRNAS can be used to personalize enzalutamide therapy.
- Trial name
- ILUMINATE (NCT02471469)
- Testing
- Enzalutamide, 160mg, 40 mg soft capsules, once daily
- Where
- 3 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Lung Cancer
Understanding Rural Patient and Provide Preferences for Mobile Lung Cancer Screening Clinics
The purpose of this study is to research patient preferences for lung cancer screening and pilot mobile units to address the barrier of access that decreases participation in lung cancer screening.
- Trial name
- NCT04926662
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Lumbar Radiculopathy
Comparison Between the Imaging Consent Form and the Existing Narrative Consent Form
This is a single-center, randomized, double-blind clinical study to compare patient comprehension and anxiety by comparing a traditional paper consent form to a multimedia consent form for patients undergoing transforaminal…
- Trial name
- NCT05874427
- Testing
- Multimedia informed consent, Standard informed consent
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Rectal Cancer, Adenocarcinoma, Chemoradiotherapy
Prehabilitation in Rectal Cancer: During Neoadjuvant Therapy vs Preoperative
Control of the effect of prehabilitation on postoperative morbidity, assessed by the Comprehensive Complication Index (CCI), in patients diagnosed with rectal cancer that will receive neoadjuvant Quimiorradiotherapy (NCRT) and…
- Trial name
- PREHAREC (NCT05286086)
- Testing
- prehabilitation
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Corporacion Parc Tauli
Doctor Patient Communication, Patient Safety
Can Video Clips Improve Patient Comprehension at the Emergency Department?
The aim of this study is to assess the utility of two interventional videos, showed to patients discharged from the ED with a diagnosis of atrial fibrillation or deep vein thrombosis.
- Conditions
- Doctor Patient Communication, Patient Safety, New Technologies in Clinical Medicine, Patient Education and Health Literacy
- Trial name
- NCT03734406
- Testing
- Videoclips
- Where
- Italy
- Volunteers
- 144 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
HIV Infections, Hepatitis B
Prospective Cohort of HIV/HBV-coinfected Patients in Europe
The overall aim of the project is to establish an international multi-cohort research platform of HIV/HBV-coinfected individuals treated with tenofovir to improve our understanding of the determinants of treatment outcomes.
- Conditions
- HIV Infections, Hepatitis B, Coinfection
- Trial name
- Euro-B (NCT04984772)
- Volunteers
- 1,107 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Parasite and Infestation Physician-Patient Diagnostic Incongruency
The Parasite and Infestation Study
Many people have evidence of bugs, parasites, and infestation, but are told by others that they cannot find a cause. This distressing and frustrating experience can last for years, as the person seeks answers.
- Trial name
- NCT07849907
- Testing
- No intervention - observational study
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Vanderbilt University Medical Center