Clinical trials: Pathologic Processes
Chronic Kidney Failure, Anaemia
Bioequivalence of a Single Subcutaneous Dose of Epoetin Beta in Healthy Japanese and Caucasian Male Subjects
A study to see how a single subcutaneous dose of Epoetin beta (NeoRecormon®) in healthy Japanese compares with a single subcutaneous dose of Epoetin beta (NeoRecormon®) in Caucasian Male subjects.
- Trial name
- NCT01085552
- Testing
- Epoetin Beta
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- InCROM Europe Clinical Research
Hypoxic Ischaemic Encephalopathy (HIE), Asphyxia
BiHiVE2 Study. The Investigation and Validation of Predictive Biomarkers in Hypoxic-ischaemic Encephalopathy.
Despite recent advances in the care of mothers and newborn infants, many infants (approximately 20 per 1000 live births) continue to need resuscitation at birth.
- Trial name
- BiHiVE2 (NCT02019147)
- Where
- 2 sites in Ireland, Sweden
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University College Cork
Depression
Exploration of the Relationship Between Inflammation and Integrity of the Blood-Brain Barrier in Suicidal Behaviour
Recent studies have revealed an association between history of suicide attempt and inflammatory markers in both the cerebrospinal fluid and the plasma.
- Trial name
- IBIS (NCT04137458)
- Testing
- Biological analysis
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Orthodontic Appliance Complication
Stability of Maxillary Anterior Teeth After Two Years of Retention in Adolescents Comparing Two Bonded and a Vacuum-formed Retainer
After orthodontic treatment 3 different retention devices will be compared.Thirty patients in each group; Group 1) Bonded retainer 13-23, Group 2)Bonded retainer 12-22 and Group 3) Vacuum-formed retainer covering all erupted…
- Trial name
- NCT04616755
- Testing
- Measuring changes of Little´s irregularity index ( sum of 5 contact point discrepancies together) measured in mm 2 years after retention have been I place.
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kronoberg County Council
Migraine, Healthy
Molecular and Functional PET-fMRI Measures of Analgesia in Migraine
The placebo effect is a phenomenon that has experienced major advances of its understanding in the last decade. However, mechanisms of placebo analgesia in chronic pain patients have yet to be compared to healthy subjects.
- Trial name
- NCT01970943
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Severe Sepsis, Organ Failure
Comparative Study of the Protein C Pathway in Septic and Non Septic Patients With Organ Failure
This is a comparative study performed in 3 groups of patients/subjects: 30 severe sepsis patients, 30 non-septic patients with organ failure, 30 healthy subjects.
- Trial name
- NCT00361725
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Failure, Chronic
Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers
The purpose of this study is to compare the absorption of dietary phosphorus following a single dose with lanthanum carbonate (1000mg) and a single dose of sevelamer carbonate (2400mg).
- Trial name
- NCT00875017
- Testing
- Lanthanum Carbonate, Sevelamer
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Shire
Pain, Chronic Post-Surgical
PERIoperative Holistic RIsk Factor SCreening in the Prevention of Persistent Pain
Assessment and management for improved wellbeing after elective surgery (PERISCOP³E-Care) Diagnostic assessment tool evaluation and cut-off determination for participation in a transmural perioperative care program
- Trial name
- PERISCOPEcare (NCT05526976)
- Testing
- PERISCOPE-care
- Where
- 2 sites in Belgium
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Chronic Periodontitis
Perio. Maint. With Diode LBR
The primary aim of this pilot study is to determine whether the test methods described feasibly achieve the goal defined for a future clinical study.
- Trial name
- NCT05276817
- Testing
- Epic Diode, HP
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Biolase Inc
Traffic Accident, Chronic Disease
Risk Level of Suffering From Traffic Injury in Primary Health Care: LESIONAT Project
Main objectives: To know the distribution of risk elements of traffic injuries Secondary objectives: To study the distribution of risk elements related with the possibility of suffering from a TI in relation to medication…
- Conditions
- Traffic Accident, Chronic Disease, Prevalence of Psychoactive Substances in Road Traffic, Relative Risk Estimation of Accident for Impaired Drivers
- Trial name
- LESIONAT (NCT00778440)
- Where
- Spain
- Volunteers
- 1,540 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Obesity, Inflammation
Inflammasome Activation and Cortisol Metabolism in Obese Women With Recurrent Miscarriage
The prevalence of obesity among women of reproductive age is increasing. Obesity represents a chronic low-grade inflammatory state and NLRP3 inflammasome plays a pivotal role in obesity-induced inflammation.
- Trial name
- NCT04275674
- Where
- Taiwan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Lung Neoplasms, Neoplasm Metastasis
Mediastinal Lymph Node Dissection in Conjunction With Pulmonary Metastasectomy From Colorectal Cancer
To study whether or not total mediastinal lymph node dissection in conjunction with pulmonary metastasectomy from colorectal cancer is associated with improved survival compared to pulmonary metastasectomy only.
- Conditions
- Lung Neoplasms, Neoplasm Metastasis, Colorectal Cancer
- Trial name
- NCT03113318
- Testing
- Total mediastinal lymph node dissection and pulmonary metastasectomy, Only pulmonary metastasectomy
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post Operative Pain
Efficacy of Desensitizing Agent,Propolis After an In-office Vital Tooth Bleaching.
This study was conducted to evaluate the efficacy of desensitizing agent Propolis, after an in -office vital tooth bleaching and to compare its desensitizing effect to traditionally used desensitizing agent fluoride varnish.
- Trial name
- NCT05569590
- Testing
- Propolis, hydrogen peroxide 35%, fluoride varnish
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Healthy Diet, Microbiota
The Link Between Diets and Health Indicators
The cohort study investigates the effect of different dietary intake among omnivorous, vegan, vegetarian and low-carb diets on health parameters and on long-term overall health.
- Trial name
- DIETE (NCT04347213)
- Testing
- Regular lifestyle in different circumstances
- Where
- Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Pain, Postoperative
Regional Anesthesia for Head and Neck Reconstruction
By utilizing regional anesthesia blocks at the surgery tissue donor sites, it can potentially reduce post-operative pain while also reducing the use of opioids.
- Trial name
- NCT04304716
- Testing
- Regional Anesthesia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Wrinkle, Rosacea
Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Evaluate the Cutera excel V™ Laser with Green Genesis and a Micro-Lens Array (MLA) Attachment
- Conditions
- Wrinkle, Rosacea, Scarring
- Trial name
- NCT03424304
- Testing
- Excel V™ Laser With Green Genesis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Immobility Syndrome, Deep Venous Thrombosis
Bedside Bike Early Mobilization Program for Inpatients
Hospital immobility leads to serious complications including muscle loss, weakness, delirium, pressure ulcers, and blood clots. Despite being medically stable, hospitalized patients spend over 90% of their time in bed due to…
- Conditions
- Immobility Syndrome, Deep Venous Thrombosis, Delirium, Hospital Acquired Condition
- Trial name
- BB-STEP (NCT07281638)
- Testing
- Bedside Bike
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Dehydration
DESHYDRAT : Assessment of the Prevalence of Dehydration Among 9 to 11 Year-old Children
The aim of the study is to determinate the prevalence of moderate dehydration among children aged 9 to 11 who are going to school.
- Trial name
- DESHYDRAT (NCT01268826)
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Inflammation, Obesity
Omega-3 Supplementation Decreases Inflammation and Fetal Obesity in Pregnancy
Randomized, double-blind placebo controlled trial of fish oil to decrease inflammation in pregnancy.
- Conditions
- Inflammation, Obesity, Pregnancy, Fetal Growth
- Trial name
- NCT00957476
- Testing
- Omega-3 Fish Oil
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Heart Failure, Chronic Obstructive Pulmonary Disease
Person-centred Care at Distance
The goal of the research project PROTECT is to translate the Person-Centred Care (PCC) principles into an eHealth (the use of information and communication technologies for health) context.
- Trial name
- PROTECT (NCT03183817)
- Testing
- Person-centred care at distance
- Where
- Sweden
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Göteborg University