Clinical trials: Parturients
Pain
Breakthrough Pain Computer Integrated Patient Controlled Epidural Analgesia
The computer-integrated patient controlled epidural analgesia (CIPCEA) system can automatically adjust the background infusion rate during combined spinal-epidural (CSE) analgesia based on the parturient's need as labour…
- Trial name
- BTP (NCT02313571)
- Where
- Singapore
- Volunteers
- 350 people
- Sponsor
- KK Women's and Children's Hospital
Adverse Effect
Phenylephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia
The purpose of this study is to investigate the suitable infusion dose of phenylephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04576663
- Testing
- Normal saline, Phenylephrine
- Volunteers
- 95 people
- Sponsor
- General Hospital of Ningxia Medical University
Morbid Obesity
Does Body Mass Index Impact the Outcome of Dural Puncture Epidural in Parturients Undergoing Normal Vaginal Delivery
Recently, the dural puncture epidural (DPE) technique has emerged as a novel method of labor analgesia. The DPE technique is a modification of the combined spinal epidural (CSE) technique, where a dural perforation is created…
- Trial name
- NCT04963452
- Testing
- Dural puncture epidural
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Obesity, Cesarean Section
Ultrasound-guided Versus Landmark-based Spinal Anesthesia in Obese Parturients Undergoing Cesarean Section
Spinal anesthesia is the most commonly used anesthetic technique for cesarean section. However, in obese parturients, identification of the optimal puncture site using anatomical landmark palpation can be challenging because of…
- Trial name
- USLMCSEOB (NCT07549776)
- Testing
- Ultrasound-guided preprocedural marking, Landmark-based palpation
- Where
- Peru
- Volunteers
- 100 people
- Sponsor
- Instituto Nacional Materno Perinatal, Peru
Pain Score (VAS)
Nebulized Dexmedetomidine or Lidocaine for Treatment of Post Dural Puncture Headache in Parturients Undergoing Elective Cesarean Section Under Spinal Anesthesia
Post-dural puncture headache (PDPH) is a well-recognized and potentially serious complication of subarachnoid block. While advancements in spinal needle design have reduced its incidence in recent years, PDPH still affects a…
- Trial name
- NCT06607861
- Testing
- saline group, dexmedetomidine group, lidocaine group
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Minia University
Post-spinal Hypotension
Variability of Perfusion Index to Predict Hypotension
About one-third of deliveries are performed by cesarean section, and this rate is increasing. The standard anesthetic technique for this procedure is spinal anesthesia (SA), which is associated with hypotension in nearly 70% of…
- Trial name
- IP-HYPO (NCT06769750)
- Testing
- leg-lift maneuver
- Where
- 2 sites in France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Episiotomy; Complications, Laceration
Comparison Low-Level Laser Therapy With Cryotherapy in Parturients With Laceration and/or Episiotomy on Pain Reduction
The changes that occur during pregnancy can lead to symptoms and complaints for women. Vaginal delivery has several benefits for both the mother and baby; however, during labor, some injuries may occur, such as lacerations and…
- Trial name
- CL (NCT06370910)
- Testing
- Low-Level Laser Therapy
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Elective Cesarean Section, Preeclampsia
Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
Preeclampsia is a multifocal syndrome reported in 2-8 % of pregnancies. It is diagnosed in the second half of pregnancy by two separate measurements of systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg…
- Trial name
- NCT04370847
- Testing
- Spinal Anesthesia, Intrathecal Bupivacaine, Intrathecal Fentanyl
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Anesthesia, Epidural
Using the CompuFlo® CathCheck™ System to Check Epidural Catheter Function Before Tubal Ligation: A Pilot Study
This pilot study evaluates the use of the CompuFlo® CathCheck™ System to assess labor epidural catheter function before reactivation for postpartum tubal ligation.
- Trial name
- NCT07720908
- Testing
- CompuFlo® CathCheck™ System Assessment
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Ohio State University
Antepartum Hemorrhage
Plethysmography Variability Index Monitoring for Parturients With Antepartum Hemorrhage
The purpose of this study is to evaluate the use of continuous noninvasive intraoperative plethesmography variability index in conjunction with Hemoglobin levels monitoring using Masimo Radical-7™ Pulse CO-Oximeter during…
- Trial name
- NCT02614053
- Testing
- Masimo Radical-7™ Pulse CO-Oximeter
- Volunteers
- 124 people
- Sponsor
- Kasr El Aini Hospital
Foetal Hypoxia
Intrapartum Sildenafil Citrate to Prevent Non Reassuring Foetal Status Among Parturients Delivering at Term
Background: Intrapartum non-reassuring foetal status is a global challenge. It is a key contributor to operative deliveries. In low- and middle-income countries, it is a major cause of perinatal deaths, hypoxic ischemic…
- Trial name
- NCT05558176
- Testing
- Sildenafil citrate
- Where
- Nigeria
- Volunteers
- 176 people
- Sponsor
- Ladoke Akintola University of Technology Teaching Hospital, Ogbomoso
Cesarean Section, Preoperative Anxiety
Effects of Sedation on Spinal Anesthesia-induced Maternal Hypotension
Background: This study was designed to investigate the effect of sedation on the occurrence of maternal hypotension in preoperatively anxious parturients undergoing urgent category-1 Cesarean section (C/S) under spinal…
- Conditions
- Cesarean Section, Preoperative Anxiety, Spinal Anesthesia, Sedation
- Trial name
- NCT02732197
- Testing
- Sedation, No sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Van Training and Research Hospital
Perinatal Depression, Ketamine
Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression
Postpartum depression is common in mothers early after childbirth and produces harmful effects not only on mothers, but also on infants and young children.
- Conditions
- Perinatal Depression, Ketamine, Cesarean Delivery, Postpartum Depression
- Trial name
- NCT03336541
- Testing
- Ketamine
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University First Hospital
Obesity, Pregnancy
Inflammation in Obese Parturients: Surgical Outcomes After Elective Caesarean Section
Hypothesis: The investigators propose that obese parturients will have an increased inflammatory response and a decreased anti-inflammatory response to the surgical and anesthetic insult of caesarean section and that this will be…
- Conditions
- Obesity, Pregnancy, Cesarean Section
- Trial name
- NCT01836315
- Testing
- Observational Study
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Manitoba
Morbid Obesity
The Ultrasound Guided Versus Land-mark Location Method for Performing Spinal Anesthesia in Obese Parturients
This study will be investigated whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the lateral position in morbidly obese pregnant women with BMI ≥ 40 who…
- Trial name
- NCT05342922
- Testing
- Ultrasound group, Landmark group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital