Clinical trials: Participation
Coronavirus Infection
The Study of "Gam-COVID-Vac" Vaccine Against COVID-19 With the Participation of Volunteers of 60 y.o and Older
The purpose of this study: to assess the safety, tolerability and immunogenicity of the drug "Gam-COVID-Vac", a solution for intramuscular injection, at various times after vaccination in volunteers over 60 years of age
- Trial name
- NCT04587219
- Testing
- Gam-COVID-Vac
- Where
- Russia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Oncologic Disease
OUTPATIENT CANCER PATIENTS: THE RELATIONSHIP BETWEEN INFORMATION OVERLOAD, SYMPTOM SEVERITY, AND EMPOWERMENT LEVEL
Examining the relationship between information load, symptom severity, and empowerment level in outpatient cancer patients is of great importance for developing holistic care plans tailored to the individual needs of patients and…
- Trial name
- CANCER PATIENT (NCT07667881)
- Volunteers
- 300 people
- Sponsor
- University of Yalova
Spinal Cord Diseases, Spinal Cord Injuries
Multi-speed Ergonomic Wheelchair
Over one million Americans rely on their upper extremities for manual wheelchair propulsion. Shoulder overuse injuries are prevalent among manual wheelchair users and these injuries often result in shoulder pain.
- Trial name
- NCT05776030
- Testing
- Single Speed Ergonomic Wheelchair, Multi-Speed Ergonomic Wheelchair
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Cervical Cancer
Discovering Factors in Cervical Cancer Patients' Clinical Trial Experiences
The percentages of participants in clinical studies haven't always been perfectly representative of a particular group. This research examines the variables that affect a patient's choice to enroll in, discontinue participation…
- Trial name
- NCT05789628
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Amyotrophic Lateral Sclerosis
A Prospective Study to Evaluate the Correlation Between Oculometric Measurements and Clinical Endpoints in ALS Patients
This is a prospective study in a cohort of about 45 patients with ALS participating in the Neurosense PrimeC drug study (NCT05357950).
- Trial name
- NCT05407428
- Testing
- NeuraLight software-based platform
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- NeuraLight
Infection, Human Immunodeficiency Virus, HIV Infections
Phase 4 Study of Dolutegravir (DTG) in Russian Federation
DTG 50 milligram (mg) tablet was approved for marketing in Russian Federation; however, DTG is not currently available for subjects at Acquired Immune Deficiency Syndrome (AIDS) Centers as it is not available for order and supply…
- Trial name
- NCT03314064
- Testing
- Dolutegravir 50 mg
- Where
- 11 sites in Russia
- Volunteers
- 43 people
- Sponsor
- ViiV Healthcare
Breast Cancer Screening
Evaluation of an mHealth Intervention to Promote Participation in Breast Cancer Screening in Argentina
We carried out with a mixed-method study including a pragmatic randomized controlled trial to evaluate effectiveness of the intervention and quantitative and qualitative evaluation of the implementation from women and…
- Trial name
- NCT06500936
- Testing
- SMS
- Where
- Argentina
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Centro de Estudio de Estado y Sociedad
Early Intervention (Education)
Early Support From Birth Onwards: ZEPPELIN
ZEPPELIN (Zurich Equity Prevention Project with Parents Participation and Integration) is a longitudinal, randomized controlled intervention study.
- Trial name
- ZEPPELIN (NCT02882763)
- Testing
- Parents As Teachers (PAT)
- Where
- Switzerland
- Volunteers
- 213 people
- Sponsor
- University of Applied Sciences of Special Needs Education
Acute Coronary Syndrome, Heart Failure
International CR Registry
The ICRR is a health services registry to establish the quality of CR delivery, and the effectiveness in terms of patient outcomes, in low-resource settings.
- Conditions
- Acute Coronary Syndrome, Heart Failure, Coronary Artery Disease
- Trial name
- ICRR (NCT04676100)
- Testing
- Cardiac rehabilitation
- Where
- Qatar
- Volunteers
- 7,000 people
- Sponsor
- University Health Network, Toronto
Alzheimer Disease
Alzheimer's Disease and Precision Medicine Research Among Native People
This project intends to address the gaps in Alzheimer's disease (AD) and precision medicine (PM) research in American Indian and Alaska Native (AI/AN) populations by comparing written and video-based materials for recruitment…
- Trial name
- NCT03448601
- Testing
- Culturally tailored brochure intervention group, Culturally tailored video intervention group
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Primary Haemostasis Disorder in Cardiac Surgery Patients
Relation Between the Value of Platelet Clot Stiffness (PCS) Obtained by Sonorheometric Method of Delocalized Hemostasis (QUANTRA®), and the Presence of a Disorder of Primary Hemostasis, in Cardiac Surgery Patients. PLAQUA-Study
The goal of this study is to determine whether the Platelet Clot Stiffness (PCS) measured by QUANTRA® is predictive of an abnormality in primary haemostasis intraoperatively in cardiac surgery performed under extracorporeal…
- Trial name
- PLAQUA (NCT06585930)
- Testing
- Blood sample
- Where
- Reunion
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
PTSD, Anxiety
Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids
The primary objective of this study is to collect insights from first responders and military personnel on their need for, use of, and interest in physical and/or mental health medical marijuana or psychedelic-assisted therapy…
- Conditions
- PTSD, Anxiety, Anxiety Disorders, Depression
- Trial name
- EMPOWER (NCT04965740)
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Empower Research Inc
Esophageal Cancer
Discovering Patterns in Experiences of Patients in Esophageal Cancer Clinical Research
Participation in clinical trials usually favors a particular demographic group. But there is limited research available to explain what study attributes affect the completion of these specific demographic groups.
- Trial name
- NCT05831150
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Obesity, Overweight
A Safety and Efficacy Study of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects Participating in an Intensive Behavior Modification Program
The purpose of this study is to determine whether a combination of naltrexone SR and bupropion SR is safe and effective in treating obesity and leads to greater weight loss when given with a group lifestyle modification program…
- Trial name
- NCT00456521
- Testing
- Naltrexone SR 32 mg/ bupropion SR 360 mg/ day, Intensive group lifestyle modification counseling
- Where
- 9 sites in United States
- Volunteers
- 793 people
- Sponsor
- Orexigen Therapeutics, Inc
Lung Cancer
Biomarkers in Predicting Response in Patients With Early-Stage Non-Small Cell Lung Cancer Previously Treated With Adjuvant Chemotherapy
This research trial studies prognostic and predictive markers in patients with early stage non-small cell lung cancer receiving chemotherapy.
- Trial name
- NCT01294280
- Testing
- Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Polyp, Adenomatous Polyp
Endoscopy Nurse Participation in Adenoma Detection Rate During Colonoscopy
Colorectal cancer (CRC) is the second most common cancer and the fourth leading cause of cancer death in Korea. Colonoscopy with polypectomy decreases the incidence and mortality from colorectal cancer.
- Conditions
- Polyp, Adenomatous Polyp, Colonoscopy
- Trial name
- NCT01124266
- Testing
- standard of care colonoscopy
- Where
- 6 sites in South Korea
- Volunteers
- 844 people, healthy volunteers welcome
- Sponsor
- Soon Chun Hyang University
Mass Screening, Colorectal Cancer
SMS Messaging as a Tool to Improve Cancer Screening Programs
The aim of this project is to assess the impact on health and economics of the implementation of text messaging (SMS) in cancer screening programs. Three interventions with SMS will be evaluated through community trials.
- Conditions
- Mass Screening, Colorectal Cancer, Breast Cancer
- Trial name
- M-TICS (NCT04343950)
- Testing
- SMS reminders to enhance colorectal cancer screening, SMS reminders to return the fecal immunochemical test at the pharmacy in CRC screening:, Invitation by SMS to previous participants in breast cancer screening:
- Where
- Spain
- Volunteers
- 44,601 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Decision Making, Knowledge, Attitudes, Practice
The Effect of a Colorectal Cancer Screening Decision Aid Tailored to Lower Educational Attainment Citizens
The aim of the trial is to test the effect of a web-based decision aid (DA) on colorectal cancer (CRC) knowledge, decisional conflict, participation rate, and informed choice (evaluated based on knowledge, attitudes and actual…
- Trial name
- LEAD (NCT03253822)
- Testing
- Decision aid
- Where
- Denmark
- Volunteers
- 15,030 people
- Sponsor
- University of Aarhus
Participation Satisfaction
Research Participant Perception of Care Project: Part II: Fielding and Validation of the Research Participant Perception Survey Derived From Focus Group-Identified Key Dimensions of the Research Participant Experience
Background: Understanding participants experiences as research volunteers is critical to improving the effectiveness of human participant protection programs and strengthening public trust in clinical research.
- Trial name
- NCT01129869
- Where
- United States
- Volunteers
- 743 people
- Sponsor
- National Institutes of Health Clinical Center (CC)