Clinical trials: Paralysis
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis
Spinal Cord Associative Plasticity Study
Spinal cord associative plasticity (SCAP) is a combined cortical and spinal electrical stimulation technique developed to induce recovery of arm and hand function in spinal cord injury.
- Conditions
- Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
- Trial name
- SCAP (NCT05163639)
- Testing
- Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP)
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Columbia University
Stroke
Fast Stepping in Stroke Patients for Fall Prediction and Prevention:Control Mechanisms and Clinical Implications
The purpose of this study was to compare the balance strategy, as well as center of pressure (COP) trajectory and parameters between healthy adults and patients with hemiplegia in response to slow- and fast-speed waist- pulling…
- Trial name
- NCT00167037
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy
Telehealth Virtual Reality Gaming on Cardiometabolic Health Among Youth With Cerebral Palsy
The primary purpose of this study is to examine the preliminary efficacy of 12-weeks of home-based exercise using consumer available virtual reality gaming technology, compared with a 12 week wait-list control group.
- Trial name
- NCT05336227
- Testing
- Virtual Reality Exergaming
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Stroke, Upper Extremity Dysfunction
Implementing Outcome Measures in Stroke Rehabilitation
The primary objective of this study is to tailor and test implementation strategies to support the adoption of two upper extremity motor outcome measures for stroke: the Fugl-Meyer Assessment and the Action Research Arm Test.
- Conditions
- Stroke, Upper Extremity Dysfunction, Hemiplegia, Hemiparesis
- Trial name
- I-STROM (NCT04888416)
- Testing
- I-STROM
- Where
- United States
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Cerebra-retinal Angiopathy
COL4A1 Gene Related Cerebra-retinal Angiopathy
This prospective multicenter cohort study aims to define the clinical, radiological and mutational spectrum of the disease related to COL4A1 gene.
- Trial name
- COL4A1 (NCT01097564)
- Testing
- COL4A1 genetic testing
- Where
- France
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bell's Palsy
Kabat Rehabilitation Technique Versus Conventional Physical Therapy in Treatment of Bell's Palsy
To evaluate the comparative effectiveness of the Kabat rehabilitation technique with conventional physical therapy along with electrical stimulation in both, for reducing facial disability in patients with Bell's palsy.
- Trial name
- NCT06083389
- Testing
- kabat technique for rehabilitation of facial palsy, electrotherapy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Laryngeal Disease, Spastic Dysphonia
Characteristics of Idiopathic Familial Voice Disorders
The purpose the study is to determine the genetic causes of specific voice disorders that run in families. Researchers are particularly interested in two conditions; 1. Spasmodic dysphonia 2.
- Conditions
- Laryngeal Disease, Spastic Dysphonia, Voice Disorder
- Trial name
- NCT00001552
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy
Protocol Validation of Dynamometric Measurement of Passive Inter-segmental Stiffness and Spasticity in Children With Cerebral Palsy
Cerebral palsy (CP) refers to a group of movement and posture disorders responsible for activity limitation due to brain damage that occurs during fetal development or during the first year of a child's life.
- Trial name
- NCT04596852
- Testing
- Assessment of the reliability of a protocol characterizing intersegmental hyper-resistance to passive stretch
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Fondation Ellen Poidatz
Paraplegia
High-intensity Interval Training for Cardiometabolic Health in Persons With Spinal Cord Injury
Persons with chronic paraplegia at an increased risk of developing cardiovascular disease and type-2 diabetes compared to the able-bodied population.
- Trial name
- NCT04397250
- Testing
- High-intensity interval training
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Bath
Alzheimer's Disease (AD), Progressive Supranuclear Palsy (PSP)
Evaluation of [18F]MNI-815 as a Potential PET Radioligand for Imaging Tau Protein in the Brain of Patients With Tauopathies
The overall goal of this imaging trial is to characterize [18F]MNI-815, a PET radioligand for imaging Tau.
- Conditions
- Alzheimer's Disease (AD), Progressive Supranuclear Palsy (PSP), Cortical Basal Syndrome (CBS), Frontal Temporal Dementia (FTD)
- Trial name
- NCT02531360
- Testing
- [18F]MNI-815 (MNI-815)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Molecular NeuroImaging
Airway
Multicenter Study of the Protector Laryngeal Mask
The study was designed to evaluate the success rate, time of insertion, sealing efficacy and security of the Protector Laryngeal Mask, a new second generation disposable supraglottic airway device, in patients undergoing elective…
- Trial name
- NCT03272776
- Testing
- Protector Laryngeal Mask airway
- Where
- Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Matilde Zaballos
Sensory Integration Disorder
Sensory Integration for Infants With Cortical Visual Impairment
Our study examines the effect of sensory integration training on sensory, motor and oculomotor skills in infants with cortical vision impairment .
- Trial name
- NCT05431647
- Testing
- Sensory integration therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Spinal Cord Injuries, Multiple Sclerosis
AIM's Writing for Healing: A Workshop for Individuals Living With Paralysis
The UAB Institute for Arts In Medicine (AIM) is currently implementing an expressive emotional writing pilot project for adults with paralysis caused by neurological conditions such as traumatic head or spinal cord injury.
- Conditions
- Spinal Cord Injuries, Multiple Sclerosis, Transverse Myelitis, Amyotrophic Lateral Sclerosis
- Trial name
- NCT04721717
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cortical/Cerebral Visual Impairment, Cerebral Palsy
Examining the Effect of Eye Gaze Technology on Children With Cortical Visual Impairment
The goal of this study is to learn about eye gaze technology's use as an assessment and intervention of visual skills and the impact on occupational performance in children with cortical/cerebral visual impairment.
- Trial name
- NCT06067607
- Testing
- eye gaze technology
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rockhurst University
Paraplegia
Exoskeleton Use With In Home Functional Activities
The purpose of this study is to observe current exoskeleton users in their home environment to determine the activities of daily living (ADLs) they are able to complete, and to identify the minor adaptations to the home…
- Trial name
- NCT06222398
- Testing
- Exoskeleton
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- A.T. Still University of Health Sciences
Facial Nerve Palsy
Facial Function Reanimation by Electrical Pacing in Unilateral Facial Paralysis.
Purpose of the trial is to study the activations of paralyzed facial muscles in a unilateral facial nerve palsy with a multi-channel electrical stimulator.
- Trial name
- NCT03496025
- Testing
- Electrical muscle stimulation
- Where
- Finland
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Cerebral Palsy, Healthy Volunteers
Assessment of Navigation Abilities in Children With Cerebral Palsy and Their Peers
Spatial navigation skills are very important in everyday activities and quality of life but spatial navigation abilities are not part of the standard process of assessment and rehabilitation of patients.
- Trial name
- NCT06320106
- Testing
- Virtual Reality baseline assessment
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea