Clinical trials: Paralysis; Stroke
Disability Physical, Brain Injuries
Impact of Custom Assistive and Adaptive Technology in Rehabilitation
Madonna's Rehabilitation Engineering Center of Excellence (REC) is continually developing custom devices for persons with disabilities.
- Conditions
- Disability Physical, Brain Injuries, Stroke, Spinal Cord Injuries
- Trial name
- NCT03567239
- Testing
- Using adaptive device.
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Madonna Rehabilitation Hospital
Facial Paralysis, Central, Stroke
Mimic Muscle Volume, Central Facial Palsy Severity and Dysphagia
70 stroke patients with central facial paralysis will be included and their demographic data will be questioned and facial nerve thickness, depressor labi inferior, depressor anguli oris, buccinator and risorius muscles will be…
- Trial name
- NCT06615297
- Testing
- ultrasonographic evaluation
- Volunteers
- 70 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Stroke, Paralysis Arm
Exergame and Robotic Therapy Impact on Tenascin-C and Functional Outcome on Stroke Patients
This clinical trial aims to compare the effectiveness of Robotic versus Exergame versus Standard therapy to improve hand function among post-stroke patients.
- Trial name
- NCT06563206
- Testing
- Exergame, Robotic, Conventional
- Where
- 2 sites in Indonesia
- Volunteers
- 48 people
- Sponsor
- Hasanuddin University
Chronic Stroke, Paralysis
Impact of Biophoton Generator on Chronic-Stroke Patients' Recovery
The purpose of this clinical research is to verify if the patients with chronic stroke can regain the ability of living independently after daily using Testa BioHealing® Biophoton Generators to increase the energy of the brain…
- Trial name
- NCT05898334
- Testing
- Active Biophoton Generators, Inactive Biophoton Generators
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- First Institute of All Medicines
Stroke, Guillain-Barre Syndrome
Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology
This study examines the use of an AI-powered virtual assistant for quickly identifying and handling neurological emergencies, particularly in places with limited medical resources.
- Conditions
- Stroke, Guillain-Barre Syndrome, Facial Palsy, Migraine
- Trial name
- AIDEN (NCT06334796)
- Testing
- Virtual Assistant
- Where
- Argentina
- Volunteers
- 10 people
- Sponsor
- Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia
Neurologic Disorder, Paralysis
EMPOWER Early Feasibility Study: Non-invasive BCI to Control a Wheelchair for People With Paralysis
Neuralis is an innovative assistive technology designed for individuals with severe neuromuscular conditions, enabling wheelchair control through EEG signals.
- Conditions
- Neurologic Disorder, Paralysis, Paralysis; Stroke, Amyotrophic Lateral Sclerosis
- Trial name
- NCT06169696
- Testing
- Intervention/Treatment
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Synaptrix Labs Inc.
Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis), Gait Disorder
Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust
The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust.
- Trial name
- ISOWALK (NCT05887440)
- Testing
- isokinetic strength training of knee extensor and flexor muscles
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Rennes University Hospital
Stroke; Paralysis, Physician's Role
Perspections of Stroke Patients and Physiotherapists in Robotic Rehabilitation
This study was a cross-sectional study. The insights of stroke patients and physiotherapists were assessed with the quantitative questionnaires. The results were provided as number, percentage, mean, and standard deviation.
- Trial name
- NCT05818202
- Testing
- Questionannire
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Pamukkale University
Neurologic Disorder, Paralysis
SWITCH II Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis
The Synchron Motor Neuroprosthesis (MNP) is intended to be used in subjects with severe motor impairment, unresponsive to medical or rehabilitative therapy and a persistent functioning motor cortex.
- Conditions
- Neurologic Disorder, Paralysis, Paralysis; Stroke, Amyotrophic Lateral Sclerosis
- Trial name
- NCT05041114
- Testing
- Motor Neuroprosthesis
- Where
- 3 sites in Australia
- Sponsor
- Synchron Medical, Inc.
Stroke, Paresis
Hemiparetic Arm Robotic Mobilization With Non Invasive Electrical Stimulation
The two cerebral hemispheres find themselves in a state of balanced mutual inhibition. A stroke with involvement of motor function leads to a reduced excitability in affected hemisphere M1 and to an increased excitability of…
- Conditions
- Stroke, Paresis, Upper Extremity Paralysis
- Trial name
- hARMonies (NCT03026712)
- Testing
- Real dual tDCS + Robotic Arm Therapy
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Stroke; Paralysis
Effects of Core Strengthening and PNF Pattern on Balance and Plantar Pressure in Chronic Stroke
To compare the effects of core strengthening and PNF on standing balance and plantar pressure in chronic stroke patients
- Trial name
- PNF (NCT05436782)
- Testing
- core strengthening exercises, Routine physical therapy
- Where
- Pakistan
- Volunteers
- 73 people
- Sponsor
- University of Lahore
Stroke; Paralysis
Application of the ICF Core Set in Stroke Patients
Sixty patients with stroke were applied a-24-item ICF Core Set for Stroke, Standardized Mini-Mental State Examination(SMMSE), Stroke Impact Scale Version(SIS), Rivermead Mobility Index(RMI) and Home Safety Checklist(HSCL).
- Trial name
- NCT05301946
- Testing
- Outcome Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Spinal Cord Injuries, Stroke
Restorative Neuromodulation for Lower Extremity Functions
The overall objective of the proposed study is to restore lower-extremity functions of paraplegic individuals. Paralysis following Stroke or spinal cord injury (SCI) result harsh sufferings including lifelong dependence on…
- Conditions
- Spinal Cord Injuries, Stroke, Paralysis
- Trial name
- NCT04171375
- Testing
- trans-spinal Electrical Stimulation (tsES)
- Where
- Hong Kong
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Ischemic Stroke, Chronic Stroke
Investigation of Neural Stem Cells in Ischemic Stroke
A study of stereotactic, intracerebral injection of CTX0E03 neural stem cells into patients with moderate to moderately severe disability as a result of an ischemic stroke.
- Conditions
- Ischemic Stroke, Chronic Stroke, Hemiparesis, Arm Paralysis
- Trial name
- PISCES III (NCT03629275)
- Testing
- CTX0E03 Drug Product and delivery device
- Where
- 23 sites in United States
- Volunteers
- 15 people
- Sponsor
- ReNeuron Limited
Ischemic Stroke, Paralysis
Lu's Acupuncture and Moxibustion Treatment on Stroke
There will be successive changes in traditional Chinese medicine rehabilitation for stroke patients with limb hemiparetic through therapy of acupuncture and moxibustion.
- Trial name
- LAMTS (NCT01806233)
- Testing
- Acupuncture, Rehabilitation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Stroke, Cerebrovascular Accident (CVA)
The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke
The purpose of this study is to evaluate if 5 consecutive sessions of PathMaker anodal DoubleStim treatment, which combines non-invasive stimulation of the spinal cord (tsDCS- trans-spinal direct current stimulation) and of the…
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Hemiparesis, Spasticity as Sequela of Stroke
- Trial name
- NCT03080454
- Testing
- anodal Doublestim
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Northwell Health
Stroke
Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery
The purpose of this study is to investigate whether benefits of training the affected hand in patients with stroke can be improved by combining training with a painless, noninvasive technique called Transcranial Direct Current…
- Trial name
- NCT01539096
- Testing
- tDCS: noninvasive brain stimulation, Constraint induced movement therapy (CIMT)
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Stroke, Cerebrovascular Disorders
Novel Brain Stimulation Therapies in Stroke Guided Expressions of Plasticity
The investigators ultimate goal is to personalize brain stimulation for stroke so outcomes of the upper limb can be maximized for each individual patient.
- Conditions
- Stroke, Cerebrovascular Disorders, Nervous System Diseases, Brain Diseases
- Trial name
- NCT03020433
- Testing
- rTMS Contralesional M1, rTMS Contralesional PMC, rTMS Ipsilesional PMC
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Stroke, Plegia
Treatment of Chronic Stroke With AMES + EMG Biofeedback
The purpose of this study is to determine if individuals who had a stroke more than one year before entering the study and who remain unable to open their affected hand are better able to sense and move their affected arm after…
- Conditions
- Stroke, Plegia, Paresis, Cerebrovascular Accident
- Trial name
- AMES (NCT01116544)
- Testing
- AMES Therapy (assisted movement and enhanced sensation)
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- AMES Technology
Stroke, Arm Paralysis
Efficacy and Safety of rTMS Plus Rehabilitation for the Improvement of the Upper Extremity in Stroke (ERES)
The rehabilitation of the upper limb after a stroke is a challenge due to its complexity and the important cerebral representation of it, particularly of the hand.
- Trial name
- ERES (NCT04124172)
- Testing
- Real rTMS (Magstim)
- Volunteers
- 24 people
- Sponsor
- Institut Guttmann