Clinical trials: Panic Disorder
Anxiety Disorders, Generalized Anxiety Disorder
Mindful Self-Compassion for Anxiety Disorders and Depression
The study will compare 8-week Mindful Self-Compassion training, compared to a control group that does not receive the intervention, on anxiety and depression symptom severity in patients with diagnosed anxiety disorders…
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Social Phobia
- Trial name
- NCT05671419
- Testing
- Mindful Self-Compassion
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Georgetown University
Panic Disorder, Agoraphobia
Effectiveness of Intensive Cognitive Behavioral Therapy in Treating Adolescent Panic Disorder and Agoraphobia
This study will evaluate the effectiveness of intensive cognitive behavioral therapy in treating adolescents with panic disorder with agoraphobia.
- Trial name
- NCT00576719
- Testing
- Intensive panic control treatment without parent involvement, Intensive panic control treatment with parent involvement, Waitlist control
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Boston University Charles River Campus
Panic Disorder
Effectiveness of Cognitive Behavioral Therapy With Panic Control Treatment for Adolescents With Panic Disorder
This study will evaluate the effectiveness of cognitive behavioral therapy with a panic control treatment component in treating adolescents with panic disorder.
- Trial name
- NCT00705380
- Testing
- Cognitive behavioral therapy (CBT) with panic control treatment (PCT) for adolescents, Waitlist control
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Boston University Charles River Campus
Panic Disorder
α-N-acetylgalactosaminidase Levels in Panic Disorder
This prospective observational cohort study investigated serum α-N-acetylgalactosaminidase levels in drug-naïve patients with Panic Disorder (PD) at baseline and after six weeks of follow-up and compared them with healthy…
- Trial name
- NCT07424911
- Testing
- No intervention was assigned as part of the research protocol.
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Schizophrenia Disorders, Major Depression
Non-Coding RNAs Gene Expression in Psychiatric Disorders
This study aims to investigate whether specific non-coding RNAs, molecules involved in the regulation of gene expression, are altered in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, major…
- Conditions
- Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- PsiRNA26 (NCT07649993)
- Testing
- Reverse Transcription Quantitative Polymerase Chain Reaction
- Where
- 5 sites in Italy
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Carmen Concerto
Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder
CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy
Anxiety-, obsessive-compulsive and trauma- and stressor-related disorders reflect a significant public health problem. This study is designed to evaluate the predictive power of a novel biomarker based on a CO2 challenge, thus…
- Conditions
- Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder
- Trial name
- NCT05467683
- Testing
- Exposure-Based Therapy
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- Jasper A. Smits
Major Depressive Disorder (MDD, Anxiety Disorder, Generalized
Serotonin Variants & Gut Microbiota in Mental Health
This observational pilot study investigates whether a broad panel of genetic variants relevant to the serotonin pathway (including serotonergic system, methylation cycle, intestinal barrier integrity, and inflammatory response…
- Conditions
- Major Depressive Disorder (MDD, Anxiety Disorder, Generalized, Stress Disorders, Post-Traumatic, Panic Disorder
- Trial name
- NCT07634458
- Testing
- SNP Genotyping and Gut Metagenomics
- Volunteers
- 30 people
- Sponsor
- Neurobiologix
Anxiety, Social Anxiety Disorder
Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4
This study seeks to understand emotion regulation in those with young adults with anxiety using real-time functional magnetic resonance imaging neurofeedback, a tool that allows individuals to control brain activity.
- Conditions
- Anxiety, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT06563310
- Testing
- Functional magnetic resonance imaging (fMRI) with Veritable-NF
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Michigan
Anxiety Disorders, Obsessive-Compulsive Disorder
Brief-intensive CBT Versus Once-weekly CBT in Anxiety-related Disorders
The goal of this clinical trial is to compare brief-intensive cognitive-behaviour therapy (CBT) with regular weekly CBT in people with anxiety-related disorders.
- Conditions
- Anxiety Disorders, Obsessive-Compulsive Disorder, Posttraumatic Stress Disorder, Hypochondriasis
- Trial name
- KOMMA (NCT05942391)
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- 6 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Amsterdam UMC, location VUmc
Panic Disorder With Agoraphobia, Panic Disorder Without Agoraphobia
A Transdiagnostic, Self-guided Internet Intervention ("Velibra") for Waitlist Patients With Anxiety Disorders
The project's aim is to investigate the effect of a transdiagnostic, self-guided, internet-based cognitive behavioral therapy program in waitlist patients with anxiety disorders.
- Conditions
- Panic Disorder With Agoraphobia, Panic Disorder Without Agoraphobia, Generalized Anxiety Disorder, Social Anxiety Disorder
- Trial name
- NCT04793828
- Testing
- Velibra
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Charite University, Berlin, Germany
Panic Disorder
A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder
The purpose of this trial is to measure the efficacy, safety, and tolerability of darigabat (25 milligrams [mg] twice daily [BID]) compared with placebo in participants with panic disorder.
- Trial name
- NCT05941442
- Testing
- Darigabat
- Where
- 31 sites in United States
- Volunteers
- 80 people
- Sponsor
- AbbVie
Anxiety Disorders, Generalized Anxiety Disorder
Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method
The study will compare the delivery of an 8-week Mindful Self-Compassion training, in-person against video-conference, on anxiety and depression symptom severity in patients with diagnosed anxiety disorders (generalized anxiety…
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT07028216
- Testing
- Mindful Self-Compassion
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Georgetown University
Anxiety, Panic Disorder
Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic Disorders
This study aims to investigate the etiology of anxiety, depression, and panic disorders, providing new evidence and insights into the root causes and effective treatments, potentially offering a novel approach to achieving…
- Conditions
- Anxiety, Panic Disorder, Mood Disorders, Depression
- Trial name
- NCT07268729
- Testing
- H pylori stool test, Bacterial stool analysis
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Anxiety
A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care
This 4-year study will examine the value of a type of a brief cognitive behavioral therapy treatment for Veterans with anxiety and worry.
- Trial name
- NCT04523779
- Testing
- Brief Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Anxiety, Panic Attacks
Using CalmiGo to Manage Anxiety and Panic Attack Symptoms in the Emergency Department
Currently, there are limited options in the management of anxiety and panic attack symptoms in the Emergency Department (ED). The most common treatment method is the use of anti-anxiety and anti-depressant medications; however…
- Trial name
- NCT03884712
- Testing
- CalmiGo
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Yves Duroseau
Panic Disorder, Generalized Anxiety Disorder
Transdiagnostic Versus Diagnosis-specific Cognitive-behavioral Therapy
The primary aim of the pilot study is to investigate the feasibility of conducting a randomized controlled trial (RCT) comparing the effects of transdiagnostic and diagnosis-specific cognitive-behavioral therapy (CBT) for…
- Conditions
- Panic Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT05249543
- Testing
- Unified protocol, Diagnosis-specific cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Karolinska Institutet
Major Depressive Episode (MDE), Major Depressive Disorder (MDD)
LHC-CIDI-5 in Hong Kong
The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12…
- Conditions
- Major Depressive Episode (MDE), Major Depressive Disorder (MDD), Persistent Depressive Disorder (PDD), Suicidal Ideation
- Trial name
- NCT06804525
- Testing
- CIDI-5, LHC-CIDI-5
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- The University of Hong Kong
Depression - Major Depressive Disorder, Schizophenia Disorder
A Novel Blood Test as a Biomarker in Mental Health
This longitudinal, observational study aims to assess whether the characteristics of a novel blood peripheral biomarker can serve as indicators for depression and schizophrenia in patients at the Royal Columbian Hospital…
- Conditions
- Depression - Major Depressive Disorder, Schizophenia Disorder, Psychosis, Mania (Neurotic)
- Trial name
- LEADING-MH (NCT06856161)
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Fraser Health
Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD)
Stepped Care Treatment for Anxiety Resilience
Childhood anxiety disorders (CAD) are common and impairing. Family based cognitive behavioral therapy (CBT) is efficacious in treating CAD.
- Conditions
- Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Separation Anxiety Disorder, Specific Phobia
- Trial name
- STAR (NCT07228143)
- Testing
- Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Andrew Wiese
Generalized Anxiety Disorder, Social Anxiety Disorder
Level of Physical Activity and Fear Learning
The proposed experimental study will be the first to investigate whether exercise vs. sitting enhances consolidation of extinction learning in adults with high AS and anxiety disorders, and the mechanistic pathways of expectancy…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT05203731
- Testing
- Exercise, Sitting
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- NYU Langone Health