Clinical trials: Palliative Treatment
Metastatic Melanoma
Standard Palliative Care Versus Standard Palliative Care Plus Polychemotherapy in Metastasized Malignant Melanoma
The purpose of this multicenter study is to examine whether the proposed randomized treatment regime results in a significantly longer survival time and higher quality of life than any additionally applied multiple chemotherapy…
- Trial name
- NCT00226473
- Testing
- Cisplatin, Vindesine, Dacarbazine (drugs)
- Where
- 13 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Dermatologic Cooperative Oncology Group
Lung Cancer, Nonsmall Cell, Stage IIIA, Lung Cancer Non-Small Cell Stage IIIB
Psychosocial eHealth in Advanced Lung Cancer
Being diagnosed with cancer impairs many areas of a person's life. Although efficacious educational, emotional and social interventions exist in this regard, they often reach few survivors and late.
- Conditions
- Lung Cancer, Nonsmall Cell, Stage IIIA, Lung Cancer Non-Small Cell Stage IIIB, Lung Cancer Non-Small Cell Stage III, Lung Cancer Stage IV
- Trial name
- NCT05497973
- Testing
- E-health ecosystem of stepped psychosocial care, Usual psychosocial care
- Where
- Spain
- Volunteers
- 152 people
- Sponsor
- Institut Català d'Oncologia
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Interstitial
BREATHE ALD: A Shared Decision-Making Intervention for Adults With Advanced Lung Disease
This study aims to: 1. Develop the BREATHE-ALD intervention for adults with Advanced Lung Disease, multiple chronic conditions, and palliative care needs and their caregivers using interviews with 10 advanced lung disease (ALD)…
- Trial name
- BREATHE-ALD (NCT04930666)
- Testing
- BRief intervention to Enhance Adherence to Treatment and HEalth advice in Advanced Lung Disease
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Columbia University
Advanced Lung Cancer
Exercise, Nutrition, and Palliative Care in Advanced Lung Cancer (ENPAL)
Background: Evidence supports exercise and nutrition as beneficial for enhancing QOL in earlier stages of lung cancer; however, there is minimal research of either intervention - and none with combined interventions - in advanced…
- Trial name
- ENPAL (NCT04575831)
- Testing
- Exercise, Nutrition, and Palliative Symptom Management
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Cancer and Non-cancer Hospice Patients
Virtual Reality for Improving Symptoms in Palliative Care
The objective of this study is to determine whether VR can ameliorate symptoms for palliative care patients within a hospice setting.
- Trial name
- VRPC (NCT05197894)
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Advanced Malignant Female Reproductive System Neoplasm
An Artificial Intelligence Algorithm for Identifying Gynecologic Cancer Patients in Need of Outpatient Palliative Care
This clinical trial tests an artificial intelligence (AI) algorithm for its ability to identify patients who may benefit from a palliative care consult for gynecologic cancer that has spread from where it first started to nearby…
- Trial name
- NCT06182332
- Testing
- Electronic Health Record Review, Internet-Based Intervention
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Mayo Clinic
Brain Metastases, Radiotherapy
Short Course Radiation Therapy in Palliative Treatment of Brain Metastases
Aim of the study is to assess efficacy of a short course radiation treatment in patients with symptomatic brain metastases from solid tumors
- Conditions
- Brain Metastases, Radiotherapy, Palliative Care
- Trial name
- NCT03525301
- Testing
- standard treatment, short course treatment
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pancreatic Cancer, Adult
To Evaluate the Preliminary Efficacy of Our Digitally Enhanced CHW-led Intervention in Newly Diagnosed PDAC
The goal of this clinical trial is to learn if a community health worker led intervention that helps facilitate palliative care works to treat newly-diagnostic pancreatic cancer.
- Trial name
- NCT07591571
- Testing
- PAL-CHW-PDAC, Usual Care with Attention Control
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Loma Linda University
Quality of Life, Gynecologic Neoplasm
Effects of Therapeutic Touch in Patients With Female Genital Neoplasia: a Randomized Controlled Clinical Trial
This is a randomized controlled prospective study on the use of therapeutic touch in patients diagnosed with gynecological cancer.
- Conditions
- Quality of Life, Gynecologic Neoplasm, Gynecologic Cancer, Palliative Care
- Trial name
- NCT03142477
- Testing
- Questionnaires, Therapeutic touch
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Federal University of Minas Gerais
Cancer, Metastatic, Family Members
An Upstream Palliative Care Intervention for Rural and African-American Advanced Cancer Family Caregivers
The burden placed on advanced cancer family caregivers (FCGs) and the toll on their mental and physical health have never been greater and is particularly pernicious for underserved groups in the Southeastern U.S., including…
- Trial name
- NCT03464188
- Testing
- Project Cornerstone
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Alabama at Birmingham
Frailty, Oncology Problem
PATH Program for for Severely Frail or Cognitively Impaired Patients Scheduled for Cancer Surgery.
This is a single center, non-blinded randomized control trial taking place at the Queen Elizabeth II hospital (QEII) in Nova Scotia.
- Conditions
- Frailty, Oncology Problem, Cognitive Impairment
- Trial name
- NCT06022666
- Testing
- Geriatric assessment
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Nova Scotia Health Authority
Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8
Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events
This clinical trial studies if enhanced outpatient symptom management with telemedicine and remote monitoring can help reduce acute care visit due to chemotherapy-related adverse events.
- Conditions
- Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
- Trial name
- NCT05038254
- Testing
- Best Practice, Patient Monitoring, Questionnaire Administration
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- M.D. Anderson Cancer Center
Palliative Care
Bringing Life to Those Near Death
The purpose of this study is to assess whether virtual reality technology can reduce anxiety, depression, and emotional distress screening scores in palliative care patients.
- Trial name
- NCT05466123
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Congestive Heart Failure, Metastatic Cancer
Advance Care Planning in the Emergency Department
This is a two-armed, parallel-design, pre-/post-intervention assessment study. The investigators will conduct a randomized controlled trial for ED GOAL on a cohort of 120 older adults with serious illness to collect…
- Conditions
- Congestive Heart Failure, Metastatic Cancer, Chronic Kidney Disease Requiring Chronic Dialysis, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05209880
- Testing
- ED GOAL
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Brigham and Women's Hospital
Head and Neck Neoplasms, Squamous Cell Carcinoma of Head and Neck
Quad Shot Versus Split Course Radiotherapy in Incurable Head and Neck Cancer
Head and neck cancer in its advanced, incurable stage causes severe symptoms such as pain, trouble swallowing, and bleeding. Palliative radiation therapy is frequently used to relieve these symptoms and improve the patient's…
- Trial name
- QSSC-HN (NCT07823309)
- Testing
- Quad Shot Radiotherapy, Split Course Radiotherapy
- Volunteers
- 40 people
- Sponsor
- Instituto Nacional de Cancerologia, Columbia
Cancer, Tumor
Community Health Workers and Precision Medicine
The purpose of this randomized controlled trial is to evaluate whether a trained community health worker (CHW) who engages with newly diagnosed patients after a diagnosis of cancer can effectively improve knowledge and receipt of…
- Trial name
- NCT04843332
- Testing
- Community Health Worker Support
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Stanford University
Parkinson's Disease
Does Outpatient Palliative Care Improve Patient-centered Outcomes in Parkinson's Disease?
The purpose of this study is to improve outcomes for persons living with Parkinson's Disease (PD) and their family caregivers. The investigators hypothesize that outpatient interdisciplinary palliative care will improve…
- Trial name
- NCT02533921
- Testing
- Interdisciplinary outpatient palliative care, Standard of Care
- Where
- 3 sites in United States, Canada
- Volunteers
- 210 people
- Sponsor
- University of Colorado, Denver
Lung Cancer, Nonsmall Cell, Lung Cancer
Palliative Thoracic ImmunoRT
The trial is designed as a prospective observational single arm study investigating stage IV non-small cell lung cancer patients who are routinely treated with a PD-1 inhibitor for indications approved by Health Canada.
- Trial name
- NCT03705806
- Testing
- Radiation combined with immunotherapy
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto
Life-limiting Cancer With Prognosis of Approximately 1 Year
Effect of Early Palliative Care on Quality of Life of Patients With Advanced Cancer: a Randomised Controlled Trial.
The World Health Organization (WHO) defines palliative care as an approach to improve the quality of life of patients and their families facing life-threatening illness, through prevention and relief of pain and of physical…
- Trial name
- IPaC (NCT01865396)
- Testing
- Interventional palliative care, Standard oncologic care
- Where
- Belgium
- Volunteers
- 268 people
- Sponsor
- University Ghent
Palliative Care
Palliative Care For Me (PCforMe)
The purpose of this study is to test the usability of PCforMe, a web-based preparation and engagement tool about palliative care, during a pre-visit pilot trial in outpatient palliative care at the Duke Cancer Institute…
- Trial name
- NCT03874195
- Testing
- Access to PCforMe for review, Access to three nationally-recognized Palliative Care websites for review
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Duke University