Clinical trials: Palliative Treatment
Carcinoma, Renal Cell
Palliative Radiofrequency Ablation in Metastatic Renal Cell Carcinoma Patients
The purpose of this study is to evaluate efficacy and safety of Radiofrequency ablation in metastatic renal cell carcinoma patients with primary tumor less than 5 cm before medical treatment.
- Trial name
- NCT00891475
- Testing
- Radiofrequency ablation; Interferon-alpha, Radiofrequency ablation; Sunitinib maleate, Sunitinib maleate
- Where
- Russia
- Volunteers
- 114 people
- Sponsor
- Kidney Cancer Research Bureau
Palliative Care, Terminal Care
Appropriate Medication Use in Dutch Terminal Care
The AMUSE trial is a multicentre stepped-wedge cluster randomized controlled trial where medication optimization of patients with a life expectancy of less than three months is investigated by using CDSS-OPTIMED (a personalized…
- Conditions
- Palliative Care, Terminal Care, Medication Therapy Management, Clinical Decision Support System (CDSS)
- Trial name
- AMUSE (NCT05351281)
- Testing
- CDSS-OPTIMED
- Where
- 7 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Prof.dr Carin (C.C.D.) van der Rijt
Palliative Care, Chronic Disease
Teaching Parents Reiki for Their Adolescents Receiving Palliative Care
The proposed study addresses National Institute of Nursing Research (NINR) priorities of advancing symptom science to "develop [and] test … novel, scalable symptom management interventions, including complementary health…
- Trial name
- NCT03896165
- Testing
- Reiki
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Ohio State University
Hope, Spirituality
Effects of Nursing Care Provided to Relatives of Palliative Care Patients on Caregivers' Spiritual Well-being and Hope
The aim of this study is to determine the effects of nursing care provided based on the Watson's Theory of Human Caring to the relatives of palliative care patients on caregivers' spiritual well-being and hope.
- Conditions
- Hope, Spirituality, Palliative Care
- Trial name
- NCT04415411
- Testing
- Nursing care based on the Theory of Human Caring
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Advanced Cancer
Psychosocial Intervention in Latino Patients with Advanced Cancer
Palliative Care focuses on symptom management and quality of life and helps patients with life-limiting illness match goals and preferences for care.
- Trial name
- NCT03763032
- Testing
- Counseling
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Colorado, Denver
Colorectal Cancer, Metastatic Cancer
Chemotherapy Via an Implantable Pump Compared With a Subcutaneous Port for Unresectable Liver Metastases in Patients With Resected Colorectal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug or giving the drugs in different ways may kill more tumor cells.
- Trial name
- NCT00002793
- Testing
- fluorouracil, leucovorin calcium
- Where
- Germany
- Volunteers
- 336 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
Durvalumab, Tremelimumab and Hypofractionated Radiation Therapy in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
This phase I/II trial studies the side effects of durvalumab, tremelimumab and hypofractionated radiation therapy in treating patients with head and neck squamous cell carcinoma that has come back (recurrent) or that has spread…
- Trial name
- NCT03522584
- Testing
- Durvalumab, Laboratory Biomarker Analysis, Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Washington
Soft Tissue Sarcoma
Patient Directed Intervention to Improve the Quality of Life for Patients With Soft Tissue Sarcoma
The primary objective of the study is to compare quality of life (QoL) between patients suffering from soft tissue sarcoma, receiving a multidimensional intervention with those receiving standard treatment.
- Trial name
- YonLife (NCT02204111)
- Testing
- Intervention
- Where
- 7 sites in Germany
- Volunteers
- 77 people
- Sponsor
- GWT-TUD GmbH
Cancer
Evaluating the CAREchart@Home™ Program for Enhancing After-hours Cancer Care
The objective of the current project is to pilot the evaluation of the health and economic benefits of having online access to health information in the context of providing telemedicine support for oncology patients receiving…
- Trial name
- NCT04232709
- Testing
- Shared electronic patient record
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Women's College Hospital
Chronic Disease, Neoplasm Metastasis
Facilitating Communication Study
This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their…
- Conditions
- Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive
- Trial name
- FCS2 (NCT03721952)
- Testing
- Facilitator-Based Intervention
- Where
- 3 sites in United States
- Volunteers
- 977 people
- Sponsor
- University of Washington
Pancreas Cancer
Tumor Registry Pancreatic Cancer
The registry aims to collect and analyse information on the antineoplastic treatment of patients with unresectable locally advanced or metastatic pancreatic cancer, treated in palliative intention (cohort 1) and patients with…
- Trial name
- AMETHYST (NCT02089269)
- Where
- Germany
- Volunteers
- 2,325 people
- Sponsor
- iOMEDICO AG
Palliative Care
Feasibility Testing of the Quality-monitoring Tool, Qdact, for the Palliative Care Research Cooperative
Few formal mechanisms for collecting, analyzing, and reporting data on quality in palliative care exist. Such infrastructure is needed to understand current clinical practices, inform quality improvement projects, and research…
- Trial name
- QFT (NCT02411305)
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Gastroparesis
Vagus Nerve Response in Gastroparesis Patients
This study aims to characterize how vagus nerve compound action potentials (CNAPs) conduct along the vagus nerve in gastroparetic patients receiving GES therapy using a flexible, non-invasive multielectrode array (MEA).
- Trial name
- NCT04207996
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Indiana University
Advanced Lung Cancer
A Clinical Study of Pain and Discomfort Associated With Advanced Lung Cancer
In this research, the patients with advanced lung cancer accompanied by pain and discomfort were treated by injecting freshly manufactured tissue permeable hyaluronan fragment HA35 into the tissue under abdominal adipose.
- Trial name
- NCT05852002
- Testing
- 35 kDa hyaluronan fragment
- Where
- Mongolia
- Volunteers
- 10 people
- Sponsor
- Nakhia Impex LLC
Demoralization
Demoralization Among Palliative Care Patients and Their Family Caregivers in Hong Kong: A Pilot Study
This study aims to explore the prevalence of demoralization among palliative care patients and family caregivers in Hong Kong and examines psychosocial factors associated with demoralization.
- Trial name
- NCT04006327
- Testing
- No intervention will be provided as this study is a cross-sectional observational study.
- Where
- Hong Kong
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Dementia
AI4HOPE Pilot Study 1 Digital Toolkit Assessment
The pilot study will develop and test a standardized assessment toolkit that will provide conclusive information with a tolerable burden for cognitively impaired patients with dementia.
- Trial name
- AI4HOPE1 (NCT06289322)
- Testing
- Digital toolkit for assessment
- Volunteers
- 150 people
- Sponsor
- University of Bonn
Terminal Illness
iLIVE Volunteer Study
The aim of this study is to develop and evaluate the implementation of an international volunteer training programme to support patients dying in the hospital setting and their families. It has the following objectives: 1.
- Trial name
- NCT04678310
- Testing
- Support from the hospital palliative and end of life care volunteer service (developed for this study).
- Where
- United Kingdom
- Volunteers
- 105 people
- Sponsor
- University of Liverpool
Life-limiting Serious Illness
Promoting Dignity, Meaningfulness and Mental Well-Being
Feasibility study to test the feasibility and acceptability of a designed personalized modular Intervention consisting of three modules, including Cancer and Living Meaningfully (CALM) Therapy, Dignity Therapy (DT), and a…
- Trial name
- NCT03744442
- Testing
- Dignity Therapy (DT) module, CALM Therapy module, Mindfulness-based interventions module
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University Hospital, Basel, Switzerland
Pecha Kuka, Palliative Care
Pecha Kuka Method About Percutaneous Endoscopic Gastrostomy for Caregivers Who Care for Palliative Care Patients
Palliative care; It was started by Dame Cicely Saunders in the 1960s as a hospice for community-based provision. Today, palliative care is defined as care that begins with the patient's diagnosis, symptom management is carried…
- Trial name
- NCT06339723
- Testing
- Pecha Kucha
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Chronic Kidney Diseases
A Pilot Study of The CKM JumpStart Tool
This is a randomized pilot study to test the feasibility and acceptability of a tool to promote discussion about conservative kidney management (CKM) among older patients with advanced CKD and their providers.
- Trial name
- NCT05753020
- Testing
- CKM Jumpstart Tool
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Washington