Clinical trials: Pain Syndrome
Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain
Determining the Prognostic Value of Continuous Intrathecal Infusion
The purpose of this study will be to determine the efficacy and the prognostic value of a continuous intrathecal prognostic infusion test in an in-hospital setting for selecting patients who would have better long term outcomes…
- Conditions
- Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain, Vertebral Compression Fracture, Failed Back Surgery Syndrome
- Trial name
- NCT03523000
- Testing
- Continuous intrathecal prognostic infusion test, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center
High Dosage Buprenorphine
High Dosage Buprenorphine as a Drug Strategy Withdrawal Assistance of Analgesics Opioid
The prevalence of analgesics opioids addiction in chronic pain patient is very difficult to know. Many studies indicated that the prevalence of addiction varied from 0% up to 50% in chronic non cancer pain patients, and from 0%…
- Trial name
- SEVROP (NCT03156907)
- Testing
- Buprenorphine
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Abdominal Pain, Irritable Bowel Syndrome
Pain Processing and Pain Neuroscience Education in Children With Chronic Abdominal Pain
The primary scientific objective of the study entails examining whether altered endogenous pain inhibition is present in children with functional abdominal pain (FAP) and irritable bowel syndrome (IBS) compared with healthy…
- Trial name
- NCT02880332
- Testing
- Usual care, Pain Neuroscience education, Extra care
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Fibromyalgia Syndrome, Primary
Fibromyalgia Study In Adults
A study to investigate ropinirole for treatment of the symptoms of fibromyalgia and in particular the widespread pain associated with this condition.
- Trial name
- NCT00256893
- Testing
- ropinirole
- Where
- 22 sites in Belgium, Denmark and 7 more
- Volunteers
- 164 people
- Sponsor
- GlaxoSmithKline
Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS)
STABLE Pilates for Hypermobility
This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.
- Conditions
- Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS), Hypermobile Spectrum Disorder
- Trial name
- STABLE (NCT07464093)
- Testing
- Pilates, Education
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brigham and Women's Hospital
Functional Abdominal Pain Syndrome, Anxiety
Neural Mechanisms of Treatment Response to ADAPT
Complex functional abdominal pain disorders (FAPD) with co-occurring anxiety are highly prevalent in children, can be very disabling, and are not responsive to currently available treatments.
- Trial name
- NCT03518216
- Testing
- ADAPT
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Michigan State University
Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Mast Cells in Male Pelvic Pain and and Lower Urinary Tract Dysfunction
The objective of this study is to evaluate inhibition of mast cells and the histamine 1 receptor (H1R) for treatment of chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS).
- Trial name
- NCT03167216
- Testing
- Cromolyn Sodium, Cetirizine Hydrochloride
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Northwestern University
Myofascial Trigger Point Pain
Percutaneous Microelectrolysis (MEP) Versus Ischemic Compression in Miofascial Trigger Points
The Percutaneous Microelectrolysis ® (MEP®) is a technique that employs a galvanic current up to 990 uA, which is applied percutaneously with an acupuncture needle connected to the cathode.
- Trial name
- NCT03708107
- Testing
- MEP, Ischemic compression
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Universitario de Ciencias de la Salud Fundación H.A. Barceló
Temporomandibular Joint Dysfunction Syndrome
Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia: Randomized Single Blinded Investigational Trial
Introduction. Temporomandibular disorders (TMD) are a group of conditions that are multifactorial in nature, and it primarily presents with symptoms of pain and decreased functional capacity.
- Trial name
- NCT02295644
- Testing
- Ultrasound Sonicator 740
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- State University of New York at Buffalo
Abdominal Pain, Functional Gastrointestinal Disorders
Efficacy of Audio Recorded Guided Imagery vs Deep Breathing Exercises on Functional Gastrointestinal Pain Disorders
The purpose of this study is to: 1. Determine if audio recorded guided imagery vs deep breathing exercises delivered via a digital media player improves abdominal pain symptoms in children with functional gastrointestinal pain…
- Trial name
- NCT03100487
- Testing
- Apple iPod Shuffle
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Baylor College of Medicine
Polycystic Ovarian Syndrome
Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Polycystic Ovarian Syndrome.
The study will be a non-blinded randomized controlled trial, consisting of two groups. Non-probability Convenience sampling will be used to recruit participants who will meet the inclusion criteria.
- Trial name
- NCT07645014
- Testing
- Neurodynamic stretches, myofascial pain release technique Interventions:
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Chronic Prostatitis, Chronic Pelvic Pain Syndrome
Different Modes of Assessment on Acupuncture Effect on Patients With Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Background: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder. Some studies have indicated that acupuncture may ameliorate the symptoms of CP/CPPS.
- Trial name
- NCT03641807
- Testing
- Acupuncture
- Where
- 4 sites in China
- Volunteers
- 60 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Interstitial Cystitis, Chronic Interstitial Cystitis
PEMF Therapy to Treat Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to gather information from the investigation of a non-pharmacological (non-drug) treatment known as low frequency pulsed electromagnetic field (PEMF).
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT04540887
- Testing
- Pulsed Electromagnetic Field (PEMF) Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Low Back Pain
Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain
To demonstrate clinically significant improvements or lack thereof in the caudal epidural patients with our without steroids. To evaluate differences in outcomes in patients receiving steroids compared to those patients…
- Trial name
- NCT00370799
- Testing
- Caudal epidural injection, Caudal Epidural Injection with generic Celestone, Caudal Epidural Injection with Celestone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Pain Management Center of Paducah
Shoulder Pain, Rotator Cuff Related Shoulder Pain
Night Pain Module for Rotator Cuff-Related Shoulder Pain
Night pain is common in people with rotator cuff-related shoulder pain and may disturb sleep and daily life. It may include difficulty falling asleep, waking because of pain, increased pain during the night, difficulty returning…
- Trial name
- NCT07838233
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 275 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Postural; Defect, Tension-Type Headache
Fascial Distortion Model in Tension Type Headache
Tension-type headache is a headache that starts from the cervical and suboccipital regions, spreads from the back of the head to the parietal, frontal and temporal regions, and is felt in the form of compression, pressure and…
- Conditions
- Postural; Defect, Tension-Type Headache, Pain, Neck, Craniovertebral; Syndrome
- Trial name
- NCT05964517
- Testing
- Fascial Distortion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- University of Gaziantep
Acquired Immunodeficiency Syndrome
Dimiracetam in Painful Neuropathies Affecting AIDS Patients
The purpose of this study is to assess the efficacy and tolerability of orally administered dimiracetam for 10 weeks to AIDS patients under treatment with antiretroviral agents presenting a disease and /or treatment related…
- Trial name
- DIPANAP (NCT01444690)
- Testing
- Dimiracetam, Dimiracetam 25 mg
- Where
- Switzerland
- Volunteers
- 244 people
- Sponsor
- Neurotune AG
Acute Coronary Syndrome
Epicardial Adipose Tissue Thickness PredIcts Obstructive Coronary Artery Disease in Acute Coronary Syndrome Patients
Epicardial adipose tissue (EAT) is a visceral adipose tissue that surrounds the heart and the coronary arteries. It is metabolically active, secreting pro- and anti-inflammatory mediators and cytokines.
- Trial name
- EPIC-ACS (NCT03787797)
- Testing
- Echocardiography
- Where
- Germany
- Volunteers
- 657 people
- Sponsor
- University Hospital, Essen
Irritable Bowel Syndrome
Exploratory Study on Dosage of Qizhi Weitong Granules in the Treatment of Irritable Bowel Syndrome （IBS)
The purpose of this study are as follows: 1) To evaluate the efficacy and safety of Qizhi Weitong granules in the treatment of diarrhea-type irritable bowel syndrome (IBS-D);2) To explore the dosage of Qizhi Weitong Granulesin…
- Trial name
- NCT05113888
- Testing
- Qizhi weitong granules(High）, Qizhi weitong granules(Low）
- Volunteers
- 120 people
- Sponsor
- China Resources Sanjiu Medical & Pharmaceutical Co., Ltd.
Spinal Cord Injuries, Central Pain Syndrome
Effect of Preventional Drug Therapy on Pain Regulation Mechanisms Among SCI
Central neuropathic pain (CNP) is defined as chronic pain due to injury or disease in the central nervous system. This pain is most common among people with a spinal cord injuries (SCI), with a prevalence of about 50%.
- Trial name
- NCT03748290
- Testing
- Pregabalin
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center