Clinical trials: Pain Syndrome
Failed Back Surgery Syndrome
Subcutaneous Peripheral Nerve Stimulation (PNS) as "Hybrid Stimulation" After Failure of Spinal Cord Stimulation (SCS) to Control the Back Pain Component in Failed Back Surgery Syndrome (FBSS) Patients.(CUMPNS Study)
Despite globally favourable outcomes of Spinal Cord Stimulation (SCS), a significant proportion of Failed Back Surgery Syndrome (FBSS) patients do not obtain adequate coverage of low back pain.
- Trial name
- NCT02110888
- Testing
- Subcutaneous peripheral nerve stimulation, SCS Only
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Poitiers University Hospital
Chronic Pain, Chronic Pain Syndrome
Weighted Blankets and Chronic Pain
The purpose of the study is to test whether the use of weighted blankets can change the experience of chronic pain and to examine if social, psychological, or health factors influence the perception of the blanket.
- Trial name
- NCT04447885
- Testing
- weighted blanket
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- University of California, San Diego
Chronic Pain Syndrome
Thermal Micro-cautery for Painful Knee Osteoarthritis
To trial a traditional pain management technique from Ayurveda in a modern way - the technique involves micro - cautery to painful areas in knee osteoarthritis for patients on a waiting list for knee replacement.
- Trial name
- TMC-PKO (NCT03460717)
- Testing
- Peripheral Nerve Field Stimulation by Thermal Micro-Cautery
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- The National Children's Hospital, Tallaght
Atherosclerosis, Stroke
Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography
This VISION study aims to investigate the role of inflammation in atherosclerosis using 68Ga- DOTATATE PET, and to validate 68Ga-DOTATATE PET imaging for the detection and quantification of vascular inflammation in the aorta…
- Conditions
- Atherosclerosis, Stroke, Transient Ischemic Attack, Chronic Stable Angina
- Trial name
- VISION (NCT02021188)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University of Cambridge
Pain, Chronic, Failed Back Surgery Syndrome
Burst Spinal Cord Stimulation (Burst-SCS) Study
Recently a new form of spinal cord stimulation therapy called burst spinal cord stimulation (Burst-SCS) is available to treat chronic pain. The goal of this study is to learn more about how Burst-SCS works to reduce chronic pain.
- Trial name
- NCT03718325
- Testing
- Burst-SCS
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Metabolic Syndrome
Serum Concentrations, Physical and Psychological Well-being in Metabolic Syndrome
The purpose of this study was to investigate the serum concentrations, physical and psychological well-being characteristics in patients having chronic musculoskeletal pain with metabolic syndrome, and to compare patients without…
- Trial name
- NCT03338868
- Testing
- Body composition, Physical activity level, Musculoskeletal pain intensity
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ataturk Training and Research Hospital
Chest Pain, Diabetes Mellitus
Chest Pain Symptoms Differences Between Diabetic Patients and Non
Cardiovascular disease is the most severe cause of death among all non-infectious diseases and accountable for 17.5 million deaths in the world.
- Trial name
- chestpaindm (NCT06718374)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Chronic Idiopathic Pain Syndrome
Laparoscopic Combined Hypo Gastric Neural Plexus Block and Uterosacral Nerve Block for Patients With Chronic Idiopathic Pelvic Pain
Often the etiology of chronic pelvic pain is not clear, as there are many disorders of the reproductive tract, gastrointestinal system, urological organs, musculoskeletal system, and psych neurological system that may be…
- Trial name
- NCT05345782
- Testing
- MARCAINE AND BETAMETHAZONE 1, MARCAINE AND BETAMETHAZONE 2
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Coronary Artery Disease, Atherosclerosis of Coronary Artery
Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold System in the Treatment of Subjects With Long de Novo Lesions
The study objective is the assessment of safety and clinical performance of Freesolve 35- and 40-mm in de novo coronary artery lesions up to 38 mm length.
- Conditions
- Coronary Artery Disease, Atherosclerosis of Coronary Artery, Myocardial Ischemia, Ischemic Heart Disease
- Trial name
- BIOMAG-LL (NCT07091682)
- Testing
- Implantation of a Sirolimus-Eluting Resorbable Coronary Magnesium Scaffold
- Where
- 14 sites in Germany, Hungary and 5 more
- Volunteers
- 100 people
- Sponsor
- Biotronik AG
Neck Pain
The Effects of Two Different Home-exercise Programmes on Women Suffering Long Term Neck/Shoulder Muscle Pain
The purpose of this study is to investigate the effects of specific neck/shoulder muscle exercises on pain, function, biochemistry and psychological factors in women suffering chronic neck/shoulder pain.
- Trial name
- NCT01876680
- Testing
- Stretching and aerobic exercise, Strength training
- Where
- Sweden
- Volunteers
- 57 people
- Sponsor
- Linkoeping University
Pain
An Exploratory Study to Assess the Effects of JNJ-39439335 on the Relief of Pain Using a Thermal-Grill Experimental Model
This exploratory study will use a thermal-grill experimental model to assess the effects of JNJ-39439335 (50 mg, single oral dose) on the relief of pain.
- Trial name
- NCT01006304
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Post-Mastectomy Chronic Pain Syndrome (Disorder)
Cryoablation for Post Mastectomy Pain Syndrome
This is a prospective, randomized, parallel-group, treatment control trial with cross-over options performed at four sites. The purpose of this study is to assess the efficacy and safety of cryoablation therapy for the treatment…
- Trial name
- NCT03293940
- Testing
- Cryoablation, Therapeutic Peripheral Nerve Block (tPNB) Injection
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Emory University
CRPS I, Causalgia
Trialing of ISS in Patients With CRPS
This is a multi-center, prospective, open-label, single-arm, observational, feasibility study. The goal of this study is to determine the feasibility of intra-spinal stimulation with optimal paresthesia coverage therapy for…
- Trial name
- NCT03954080
- Testing
- Intraspinal-optimal stim therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Millennium Pain Center
Impingement Syndrome, Impingement Shoulder
PMT Versus IASTM in Subacromial Impingement Syndrome
This assessor-blinded, three-arm, parallel-group randomized controlled trial will investigate the additional effects of percussion massage therapy and instrument-assisted soft tissue mobilization in individuals with subacromial…
- Conditions
- Impingement Syndrome, Impingement Shoulder, Shoulder Pain
- Trial name
- NCT07756203
- Testing
- Percussion massage therapy device, Instrument-assisted soft tissue mobilization device, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Emre DANSUK
Cardiac Dysfunction, Neurocognitive Disease
Football Players Health Study In Person Assessments Study
The aim of the Football Players Health Study (FPHS) is to advance the understanding of the complex and inter-related pathways that can develop into player related illness and disability.
- Conditions
- Cardiac Dysfunction, Neurocognitive Disease, Chronic Pain, Sleep Apnea
- Trial name
- IPA (NCT03866564)
- Testing
- Echocardiography, Neuropsychological Testing, Quantitative Sensory Testing
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Lung Diseases, Lung Cancers
Optimizing Post-Thoracotomy Pain Management: Comparing Erector Spinae vs. Paravertebral Block in Thoracotomy Patients
This prospective, observational study included ASA class II-III patients aged 18-70 years who underwent elective unilateral lobectomy via a thoracotomy.
- Trial name
- NCT06964698
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Interstitial Cystitis, Bladder Pain Syndrome
Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome
Interstitial cystitis / bladder pain syndrome (IC/BPS) is a debilitating condition that affects millions of women in the United States.
- Trial name
- T3STOPBPS (NCT05485207)
- Testing
- Transvaginal botulinum toxin A (BTA) injection
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Low Back Pain, Mechanical, Lower Cross Syndrome
Effects of Post-Isometric Relaxation and Myofascial Release on Low Back Pain With Lower Cross Syndrome
This randomized controlled trial aims to evaluate the combined effects of post-isometric relaxation and myofascial release on pain, flexibility, and functional disability in individuals with low back pain associated with lower…
- Conditions
- Low Back Pain, Mechanical, Lower Cross Syndrome, Hamstring Muscle Tightness
- Trial name
- NCT07496099
- Testing
- post isometric relaxation, MYOFASCIAL RELEASE, Conventional Static Stretching
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Karachi
Myofascial Pain Syndrome, Temporomandibular Disorder
The Effectiveness of a Physiotherapy Technique in Patients With Chronic Myofascial Temporomandibular Disorder
Participants with chronic orofacial pain caused by masticatory and neck muscles will be distributed in two groups, both followed with the same occlusal and self-care treatment.
- Trial name
- TrP-TMD (NCT03619889)
- Testing
- Manual pressure release technique on trigger points.
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Universidad Complutense de Madrid
Carpal Tunnel Syndrome
Mechanisms of Neural Mobilization in the Treatment of Chronic Pain
The purpose of this study was to determine the effect of a manual therapy technique (neural mobilization) on measures of clinical pain and function, experimental pain sensitivity, and on the function of the median nerve in…
- Trial name
- NCT00929123
- Testing
- neural mobilization, healthy controls
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida