Clinical trials: Pain Management
Hernioplasty, Cholecystectomy, Laparoscopic
Intensive Monitoring of Post-surgery Pain in Major Ambulatory Surgery
Moderate to severe acute postoperative pain (APP) during part of the postoperative period is a barrier that hinders the central objective of perioperative medicine, which is to achieve an optimal postoperative recovery process.
- Conditions
- Hernioplasty, Cholecystectomy, Laparoscopic, Haemorrhoidal Surgery, Knee Arthroscopy
- Trial name
- NCT07252817
- Testing
- Intensive monioring group, Standard monitoring group
- Where
- Spain
- Volunteers
- 280 people
- Sponsor
- Consorci Sanitari del Maresme
Acute Chest Pain
Clinical Profile, Management Strategies, And Outcome Of Patients With Acute Chest Pain In Regional Referral Hospitals In Tanzania. Protocol For A Prospective, Multi-Centre Cohort Study
This study aims to understand how patients with acute chest pain are evaluated, treated, and cared for in emergency departments (EDs) at regional hospitals in Tanzania.
- Trial name
- NCT06925568
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 317 people
- Sponsor
- Jakaya Kikwete Cardiac Institute
Acute Pain
Efficacy of Gabapentin vs. Placebo for Adjuvant Pain Control Following Acute Rib Fractures
A Multi-center, Randomized Controlled Trial of the Efficacy of Gabapentin vs. Placebo for Adjutant Pain Control Following Acute Rib Fractures.
- Trial name
- NCT02856750
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Postoperative Pain
Effectiveness of Magnetic Therapy on Pain Intensity
Static magnetic therapy is increasingly used to alleviate pain; however, its efficacy has not been determined yet. The aims of this proposal are to evaluate the effect of magnetic therapy on pain intensity levels, opioid…
- Trial name
- NCT00104533
- Testing
- Magnets
- Where
- Colombia
- Volunteers
- 164 people
- Sponsor
- Javeriana University
Stress, Pain
Evaluation of the Surgical Pleth Index During Spinal and General Anesthesia
The Surgical Pleth index (SPI) has been introduced as a non invasive tool to "measure" stress and pain during surgery. Preliminary studies were performed in patients under general anaesthesia with propofol and remifentanil.
- Trial name
- NCT00789438
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- University Hospital Schleswig-Holstein
Low Back Pain
Capacitive-Resistive Energy Transfer (CRET) for the Treatment of Low Back Pain
This retrospective observational study compares the effectiveness of two CRET therapies in adults with physical dysfunction. It evaluates whether the UNIQ electrode Fisiowarm 7.0 improves lumbar ROM (Schober test) and reduces…
- Trial name
- NCT06728215
- Testing
- CRET 1, CRET 2
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- D&V FARMA srl
Pain Management, Parasternal Block
Influence of Superficial Parasternal Intercostal Plane Block on Internal Thoracic Artery Caliber to Facilitate Surgical Harvesting in CABG
Influence of Superficial Parasternal Intercostal Plane Block (SPIPB) on Internal Thoracic Artery (ITA) Caliber and Surgical Harvesting Efficiency in Coronary Artery Bypass Grafting (CABG)
- Conditions
- Pain Management, Parasternal Block, CABG Graft Integrity
- Trial name
- IMA CABG PIPB (NCT07663435)
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Cesarean Section
Transversus Abdominis Plane Block Versus Wound Infiltration for Analgesia After Cesarean Delivery
Adequate pain control after cesarean delivery is a major concern both for parturient and for obstetric anesthesiologists, and it usually comprises a combination of systemic and regional techniques.The transversus abdominis plane…
- Trial name
- NCT03498118
- Testing
- 20 mL of bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Aswan University Hospital
Ultrasound, Serratus Anterior Plane Block
Ultrasound Guided Serratus Anterior Plane Block Versus Thoracic Erector Spinae Plane Block for Post Operative Analgesia in Pediatrics Undergoing Thoracotomy
This study is designed to compare the post operative analgesic effect of serratus anterior plane block versus thoracic erector spinae plane block in pediatrics undergoing thoracotomy
- Conditions
- Ultrasound, Serratus Anterior Plane Block, Thoracic Erector Spinae Plane Block, Post Operative Analgesia
- Trial name
- NCT06862518
- Testing
- Control group, Serratus Anterior Plane Block (SAPB) group, Erector Spinae Plane Block (ESPB) group
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
Anesthesia, Anterior Cruciate Ligament Reconstruction
Postoperative Analgesic Benefit of iPACK Block in the Anterior Cruciate Ligament Reconstruction Surgery
This randomised clinical trial evaluates the analgesia provided by an iPack block associated with an adductor canal block in patients who undergo anterior cruciate ligament reconstruction surgery, compared to an adductor canal…
- Trial name
- Liga-PACK (NCT05136352)
- Testing
- adductor canal block, iPACK block
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Toulouse
Anesthesia, Spinal, Arthroplasty, Replacement, Knee
Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty
The purpose of this study is to determine if a shorter-acting spinal anesthetic called mepivacaine has advantages over a longer-acting medication called bupivacaine.
- Conditions
- Anesthesia, Spinal, Arthroplasty, Replacement, Knee, Pain Management, Early Ambulation
- Trial name
- NCT02980926
- Testing
- Mepivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Anterior Cruciate Ligament Injury
A Novel Analgesia Technique for ACL Reconstruction
A comparison of two anesthetic techniques-- the Adductor Canal Block (ACB) and the Adductor Canal Block with Infiltration of the interspace between the popliteal artery and the capsule of the posterior knee (ACB/IPACK)-- in…
- Trial name
- NCT03292926
- Testing
- Bupivacaine, Ultrasound, Dexamethasone
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative
Erector Spinae Plane Block vs Erector Spinae Plane Block With Serratus Anterior Plane Block in Thoracic Surgery
This pilot study will prospectively compare continuous Erector Spinae Plane block (ESP) versus combination of continuous Erector Spinae Plane block and single shot Serratus Anterior Plane block for post-operative pain management…
- Trial name
- NCT04349774
- Testing
- Control Group - ESP block with SAP block, Treatment Group - ESP block with SAP normal saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Anna Uskova
Analgesia
Ultrasound Guided Retrolaminar Versus Erector Spinae Plane Block for Postoperative Analgesia
Thoracic epidural anesthesia (TEA) and paravertebral block (PVB) have been utilized to give perioperative regional anesthesia in the trunk.
- Trial name
- NCT04531215
- Testing
- ultrasound guided Retrolaminar Block, ultrasound guided Erector Spinae Plane
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Piriformis Syndrome
Effectiveness of Instrument Assisted Soft Tissue Mobilization in Management of Piriformis Syndrome
This study aims to assess the effectiveness of IASTM on pain, ROM, Disability and Quality of life among Piriformis Syndrome patients.
- Trial name
- NCT06406023
- Testing
- Conventional treatment, Instrument assisted soft tissue mobilization
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Cervical Radiculopathy
Conservative Therapy Versus Epidural Steroids for Cervical Radiculopathy
The main objective of this study is to determine whether interventional treatment (i.e. epidural steroids), conservative therapy, or the combination, is superior for cervical radiculopathy.
- Trial name
- NCT01144923
- Testing
- Gabapentin and/or Nortriptyline, Physical therapy, Epidural Steroid Injections (ESI), Combination treatment
- Where
- 2 sites in United States
- Volunteers
- 169 people
- Sponsor
- Johns Hopkins University
Elective Bilateral Myringotomy
Sublingual Ketorolac Compared to Intranasal Dexmedetomidine for Postoperative Analgesia in Pediatric Patients Undergoing Bilateral Myringotomy
The investigators aim to compare intranasal dexmedetomidine in a dose of 1ug.kg-1 with sublingual ketorolac in a dose of 1mg.kg-1 on postoperative behaviour in those children undergoing BMT during their PACU stay
- Trial name
- NCT03742180
- Testing
- intranasal dexmedetomidine, sublingual ketorolac
- Where
- Egypt
- Sponsor
- Mansoura University
Perineal Tear, Perineal Laceration (Obstetric)
Comparison Between Rectal Suppository Acetaminophen and Diclofenac Sodium as Analgesia for Postpartum Perineal Tear
To assess the prevalence of pain score for perineum pain following childbirth followed by phase 2 study to assess the analgesic effectiveness of acetaminophen and diclofenac rectal suppository in postpartum perineum pain…
- Trial name
- SuPPerP (NCT03041779)
- Testing
- Diclofenac Sodium 50Mg Suppository, Paracetamol 500Mg Suppository
- Volunteers
- 909 people
- Sponsor
- Clinical Research Centre, Malaysia
Pain
Investigation of Rate + Extent of Excretion of Radioactivity in Urine +Faeces After Oral Administration of [14C]AZD2066
The aim of this study is to get information about absorption, distribution, metabolism and excretion as well as the tolerability and safety of AZD2066 in healthy male volunteers.
- Trial name
- NCT00829088
- Testing
- AZD2066
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Surgery, Pain, Postoperative
Added Value of Systemic Lidocaine on Postoperative Pain, Opiate Use and Nausea After Knee Arthroscopy
Local intra-articular injection of anesthetics (LIA) is increasingly used during knee arthroscopy for pain relief. The LIA can only be performed at the end of surgery as the knee joint is continuously flushed during the…
- Conditions
- Surgery, Pain, Postoperative, Nausea, Postoperative, Opioid Use
- Trial name
- NCT03599427
- Testing
- systemic lidocaine
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares