Clinical trials: Pain Interference
Negative Affectivity, Non-invasive Brain Stimulation
Neural Mechanisms of Interpersonal Expectations on Negative Affect
The goal of this clinical trial is to learn whether non-invasive brain stimulation, called transcranial temporal interference stimulation (tTIS), can reduce negative affect, and how expectations shaped by care providers influence…
- Conditions
- Negative Affectivity, Non-invasive Brain Stimulation, Placebo Effect, Expectations
- Trial name
- NCT06980090
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Chronic Nonspecific Low Back Pain
Dual-Task Core Stabilization Training in Chronic Nonspecific Low Back Pain
This study will investigate whether adding cognitive tasks to core stabilization exercises improves the ability to perform physical and mental tasks simultaneously in adults with chronic nonspecific low back pain.
- Trial name
- DT-CSE (NCT07894965)
- Testing
- Dual-Task Core Stabilization Exercise, Single-Task Core Stabilization Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Karabuk University
Chemotherapy-induced Peripheral Neuropathy, Cancer Survivors
Effectiveness of Online ACT for Pain Interference in Cancer Survivors With Chronic Painful CIPN
Rationale: An average of 30% of adult cancer survivors suffers from chemotherapy-induced peripheral neuropathy (CIPN) ≥ 6 months after completion of chemotherapy, and their quality of life (QoL) is strongly affected due to these…
- Trial name
- QLIPP-CIPN (NCT05371158)
- Testing
- Online intervention
- Where
- Netherlands
- Volunteers
- 112 people
- Sponsor
- Daniëlle van de Graaf
Back Pain
Pain Assessment and Quality of Life in Back Pain Patients: Role of Milnacipran
1. To show that patients with greater pain sensitivity will show greater improvement in their symptoms (self-reported pain intensity, mood, sleep, and quality of life) than those with lower pain sensitivity, based on QST, after…
- Trial name
- NCT01221740
- Testing
- Savella
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Pain Interference
Radicle Relief RAL™: A Study Assessing the Impact of Health and Wellness Products on Pain Relief and Related Health Outcomes
Radicle Relief RAL: A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on pain relief and related health outcomes.
- Trial name
- NCT07262775
- Testing
- Pain Relief Supplement Active Product 1
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Advanced Breast Cancer, Advanced Prostate Cancer
Engage Psychosocial Intervention for Cancer Symptoms
The goal of this clinical trial is to test the efficacy a new psychosocial symptom management intervention called ENGAGE for patients with Stage IV breast, prostate, lung, or colorectal cancer.
- Conditions
- Advanced Breast Cancer, Advanced Prostate Cancer, Advanced Lung Cancer, Advanced Colorectal Carcinoma
- Trial name
- Engage (NCT06555588)
- Testing
- ENGAGE, Supportive Care
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Duke University
Tibia Fracture
Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures
The proposed study is a two arm, pragmatic, randomized controlled multicenter Phase III noninferiority trial. 1,000 patients with tibia fractures treated with intramedullary (IM) nail will be randomized into two treatment arms.
- Trial name
- NCT05000281
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Major Extremity Trauma Research Consortium
Opioid-use Disorder, Stress Related Disorder
Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)
This will be a randomized controlled trial (RCT) designed to compare live-online Mindful Recovery Opioid Care Continuum (M-ROCC) groups with a live-online control group on the primary outcome of number of biochemically confirmed…
- Conditions
- Opioid-use Disorder, Stress Related Disorder, Anxiety, Pain Interference
- Trial name
- Mindful-OBOT (NCT04278586)
- Testing
- Live-Online M-ROCC, Live-Online Control
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Cambridge Health Alliance
Chronic Postsurgical Pain, Acute Postoperative Pain
Persistent Pain and Its Impact on Daily Life After Lung Surgery
This study will examine how pain changes over the first six months after lung surgery and how it affects daily life. It will include adults scheduled for surgery to remove part or all of a lung.
- Conditions
- Chronic Postsurgical Pain, Acute Postoperative Pain, Pain-Related Functional Interference
- Trial name
- NCT07853456
- Testing
- Longitudinal Assessment of Pain and Pain-Related Functional Interference
- Volunteers
- 350 people
- Sponsor
- Aerospace Center Hospital
Spinal Cord Injury, Pain Management
Solving SCI Pain: Pain Recovery Tools for SCI
Brief Summary The goal of this clinical trial is to evaluate whether a neuroscience-informed, peer-led self-management program can promote behavior change and reduce pain interference in adults with spinal cord injury (SCI) and…
- Conditions
- Spinal Cord Injury, Pain Management, Self-management Behaviors
- Trial name
- NCT07212725
- Testing
- Solving SCI Pain: Peer-Led Pain Self-Management Pain Tools Program
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of British Columbia
Chronic Pain, Adverse Childhood Experiences
Traumatic Events in Childhood, Attachment, Pain Perception, Epigenetic Marks, Quality of Life and Resilience.
In the present research study, aiming to explore the links between several psychological factors and chronic pain, the research seeks to develop an inclusive framework to investigate the role of adverse childhood experiences…
- Conditions
- Chronic Pain, Adverse Childhood Experiences, Attachment Styles, Chronic Stress
- Trial name
- NCT06077097
- Testing
- Biological samples
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University of Lorraine
Chronic Pain, Cesarean Section Complications
Reducing Chronic Pain Following Cesarean Delivery
This pilot study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain relief skills class, to postpartum women with ongoing pain and/or pain interference following cesarean…
- Conditions
- Chronic Pain, Cesarean Section Complications, Postpartum
- Trial name
- NCT07799883
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Chronic Pain
Developing a Tailored Psychosocial Education Intervention for Chronic Pain Management for Asian Americans
Chronic pain is a major population health issue affecting more than 100 million Americans and variations in chronic pain experiences have been widely documented, including differences in pain burden and likelihood of…
- Trial name
- NCT06725329
- Testing
- A tailored psychosocial education intervention
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- George Washington University
Temporomandibular Disorders (TMD)
Journaling Intervention for Temporomandibular Disorder (TMD) and Chronic Overlapping Pain
The goal of this clinical trial is to learn whether a 2-week gratitude journaling activity is feasible and acceptable for individuals with Temporomandibular Disorder (TMD) and chronic overlapping pain.
- Trial name
- NCT06977100
- Testing
- Gratitude, General Wellness
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Chronic Pelvic Pain
Empowered Relief for Chronic Pelvic Pain
Primary Aim To determine if the addition of empowered relief therapy to standard treatment is superior to standard treatment alone in patients with chronic pelvic pain as measured by pain interference in patients with chronic…
- Trial name
- ER_for_CPP (NCT07812857)
- Testing
- Empowered Relief (ER) Therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Bandages, Muscle Soreness
Kinesio Taping in Muscle Damage Response Induced by Eccentric Exercise
Sixty volunteers with a mean age of 21,8 ± 2,6 years participated in this study, randomly distributed into one of the following groups: control, Kinesio taping group with tension in the anterior arm region and Kinesio taping…
- Trial name
- NCT02945098
- Testing
- Kinesio Taping
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Musculoskeletal Pain, Questionnaire
Validation of the Polish Version of the MPIIQM Questionnaire for Musicians
The aim of this study, originally named "Cross-Cultural Adaptation and Validation of the Musculoskeletal Pain Intensity and Interference Questionnaire for Musicians of the Polish Population (MPIIQM-P)" is the enlargement of…
- Trial name
- NCT05903300
- Testing
- Surveys and Questionnaires
- Where
- Poland
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Anna Cygańska
Hemophilic Arthropathy, Chronic Pain
Multicomponent Pain Self-Management in Adults With Haemophilic Arthropathy
Background: Haemophilic arthropathy is associated with chronic pain, functional limitation and impaired quality of life. Pain interference may also be influenced by cognitive, emotional and behavioural factors.
- Conditions
- Hemophilic Arthropathy, Chronic Pain, Hemophilia A, Hemophilia B
- Trial name
- NCT07860632
- Testing
- Multicomponent pain self-management programme
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Hemophilia
Central Pain Mechanisms and Clinical and Psychological Factors Associated With Pain Interference in Daily Life in Adults With Hemophilia and Hemophilic Arthropathy
Introduction. Chronic pain is a frequent complication in adults with hemophilia and hemophilic arthropathy that affects functionality and quality of life.
- Trial name
- NCT07516730
- Where
- Spain
- Volunteers
- 141 people
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Chronic Low Back Pain
Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)
The primary purpose of the study was to test the efficacy of 2 tablets (twice daily) of ABT-712, compared to placebo, administered over a 4-week period in participants with moderate to severe mechanical chronic low back pain…
- Trial name
- NCT00761150
- Testing
- ABT-712
- Where
- 32 sites in United States
- Volunteers
- 308 people
- Sponsor
- AbbVie (prior sponsor, Abbott)