Clinical trials: Pain Intensity
Postoperative Pain
Does Ultrasound Improve Procedural Time in the Lateral Popliteal Approach to the Sciatic Nerve in Obese Patients
Ultrasound have been shown to improve the time needed to locate and block nerves in the non obese population. However, its utility is still unknown in the obese population.
- Trial name
- NCT01579747
- Testing
- Ultrasound, Nerve stimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of New Mexico
Stroke, Shoulder Injury
STRIPS: Shoulder Taping Reduces Injury and Pain in Stroke
Background and Rationale: The most commonly seen disabilities in stroke patients are shoulder injuries such as shoulder pain, glenohumeral subluxation, spasticity of shoulder muscles, soft-tissue trauma, rotator cuff tears, and…
- Trial name
- STRIPS (NCT01062308)
- Where
- 2 sites in India
- Volunteers
- 162 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
PVD, Arterial Ulcers
Effect of HPIPC for the Treatment of Ischemic Ulcers in Subjects With PAD
To evaluate the effects of HPIPC for the treatment of symptoms of PAD
- Trial name
- NCT01420289
- Testing
- High pressure intermittent pneumatic compression (HPIPC), Excercise
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Calvary Hospital, Bronx, NY
Pain Management
Pudendal Enhancement of Enhanced Recovery After Surgery (ERAS) for Reconstructive Surgery (PEERS)
Patients will undergo their vaginal reconstructive surgery in the usual manner, but will also be randomly assigned on the day of surgery to either receive the extra injection of numbing medication at the onset of surgery or not.
- Trial name
- NCT04171050
- Testing
- Local anaesthetic, Pudendal Nerve Block plus anesthesia
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, Los Angeles
Pain
Pharmacokinetic Evaluation of EXPAREL in Adults Undergoing Tonsillectomy
The purpose of this study is to characterize the pharmacokinetic (PK) profile of a single dose of EXPAREL (133 mg/10 mL) administered intraoperatively per normal infiltration for prolonged analgesia in 12 adult subjects…
- Trial name
- NCT02199574
- Testing
- EXPAREL
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Skin Aging of Dorsal Hands
Comparing Pain, Safety and Effectiveness of Restylane Skinboosters Vital Lido and Vital Without Lido in Dorsal Hand
This is a randomized, multi-center, split-hand, subject-blinded study comparing pain, safety and effectiveness of Restylane Skinboosters Vital Lidocaine and Restylane Vital without lidocaine for improving appearance of the dorsal…
- Trial name
- NCT06372782
- Testing
- Restylane Skinboosters Vital Lidocaine, Restylane Vital
- Where
- 3 sites in China
- Volunteers
- 90 people
- Sponsor
- Galderma R&D
Pain
"Lidocaine 4% Cream (LMX4) vs Placebo for Pain Due to Lumbar Puncture in Infants 0-60 Days of Age."
The study's hypothesis is LMX4 cream, a topical anesthetic cream, will reduce the pain of infants undergoing Lumbar Puncture (spinal tap).
- Trial name
- NCT00533468
- Testing
- Lidocaine Cream 4%
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- State University of New York at Buffalo
Chronic Pain
Single Session Class to Reduce Opioid Use in Chronic Pain
Prescription opioids are one of the most commonly used treatments for chronic pain, despite limited evidence of their efficacy and high morbidity and mortality risks.
- Trial name
- NCT03950791
- Testing
- Pain Catastrophizing Class, Health Education
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Stanford University
Acute Pain
ANI Versus Standard Care in Surgical Patients Receiving Balanced Sevoflurane-Fentanyl Anesthesia
This study aims to be a randomized, controlled study of ANI-guided opioid administration versus standard clinical practice in surgical patients undergoing general anesthesia with balanced sevoflurane-fentanyl.
- Trial name
- NCT03684590
- Testing
- ANI-guided opioid administration, Standard opioid administration
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pain
Effect of IV Lidocaine Infusions on Pain
Our goals for this study involve using intravenous lidocaine as it is normally used in the Stanford Pain Management Center to assess the effect of intravenous lidocaine on chronic pain.
- Trial name
- NCT00725504
- Testing
- Intravenous lidocaine
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Stanford University
Pain, Postoperative
Opioid & Steroid Use Following Tonsillectomy in Pediatric Patients
The purpose of this study is to determine if a post-operative course of oral dexamethasone affects opioid usage in pediatric patients undergoing tonsillectomy.
- Trial name
- NCT04541147
- Testing
- Dexamethasone, Analgesics
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Migraine, Healthy
Molecular and Functional PET-fMRI Measures of Analgesia in Migraine
The placebo effect is a phenomenon that has experienced major advances of its understanding in the last decade. However, mechanisms of placebo analgesia in chronic pain patients have yet to be compared to healthy subjects.
- Trial name
- NCT01970943
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post-operative Pain
Effectiveness of Continuous Femoral Nerve Block Versus Single Shot Femoral Nerve Block for Pain Control
Both single shot femoral nerve block and continuous femoral nerve block with catheter have been shown to be effective for pain control after anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT01916590
- Testing
- Bupivicaine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Colorado, Denver
Pain, Postoperative, Acute Pain
Efficacy and Safety of VVZ-149 Injections in Patients Undergoing Laparoscopic Colectomy
The purpose of this phase 3 study is to evaluate the efficacy and safety of VVZ-149 Injections for the treatment of postoperative pain following laparoscopic colectomy.
- Trial name
- NCT05764525
- Testing
- VVZ-149 Injections
- Where
- 5 sites in South Korea
- Volunteers
- 285 people
- Sponsor
- Vivozon Pharmaceutical Inc.
Knee Osteoarthritis, Knee Pain
The Effect of AposTherapy on Knee Pain
AposTherapy is a home based exercise program utilizing footwear that causes exercise with normal activity that may significantly improve function in patients with knee osteoarthritis since patients with knee osteoarthritis have…
- Trial name
- AposKnee (NCT03171168)
- Testing
- AposTherapy, Traditional Physical Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Montefiore Medical Center
Chronic Migraine, Headache, Episodic Migraine
Occipital Blocks for Acute Migraine
Migraine affects 10-28% of children and adolescents and yet 20-30% of patients are ineffectively treated with current oral and nasal options.
- Trial name
- NCT03526874
- Testing
- Lidocaine 4% Topical Application Cream [LMX 4], Lidocaine Hydrochloride 2 mg/mL Injectable Solution, Normal Saline
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Children's Hospital of Philadelphia
Lumbar Spinal Stenosis
Sterile Amniotic Fluid Filtrate Epidural Injection.
There is a large population of patients with lumbosacral radicular pain due to spinal stenosis who do not respond to physical therapy or oral medication management, yet wish to avoid spinal surgery or are simply not candidates…
- Trial name
- NCT04537026
- Testing
- Amniotic Fluid Allograft, Dexamethasone sodium phosphate
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Utah
Ocular Inflammation and Pain After Cataract Surgery
A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of APP13007 to Treat Inflammation and Pain After Cataract Surgery
This is a Phase 2a, 2-part study (designated Parts A and B) that will evaluate APP13007 dose strength and dosing frequency in a randomized double-masked fashion for comparison to the respective matching vehicle placebo.
- Trial name
- NCT04089735
- Testing
- APP13007, 0.05%, APP13007, 0.1%
- Where
- 9 sites in United States
- Volunteers
- 165 people
- Sponsor
- Formosa Pharmaceuticals, Inc.
Elective Reconstructive Surgery Population
The Effect of Healing Touch on Sleep
Healing Touch improves measures of sleep the night prior to surgery, thus improving surgery-related morbidity.
- Trial name
- Sleep7 (NCT01870076)
- Testing
- Healing Touch, Control, Presence
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Chronic Pain Following Thermal Burn Injury
Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury
The goal of this study is to develop a safe, effective, and readily available treatment that will prevent chronic pain following Major Thermal Burn Injury (MThBI).
- Trial name
- NCT03313076
- Testing
- Omega-3 fatty acids (fish oil), Vitamin D3 (cholecalciferol)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of North Carolina, Chapel Hill
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.