Clinical trials: Pain Intensity
Analgesics, Opioid, Anesthetics, Local
Opioid Use of Local Anaesthetic Agents in Open Heart Surgery and Its Effect on Recovery
The aim of this randomized controlled study was to investigate the effect of injecting local anesthetic agents into the sternotomy incision site and around the drains on the amount of opioids used in the postoperative period and…
- Trial name
- NCT06642077
- Testing
- LIDOFAST 40 mg/2 ml + 0.025 mg/2 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Erythema, Pain
Ultra Violet B Radiation (UVR) Study of Strontium Chloride Hexahydrate Hydrocortisone
Double blinded (subject and observer), randomised, active (hydrocortisone (HC)) controlled study of the effect of strontium chloride hexahydrate on ultraviolet B radiation (UVR) induced signs of inflammation (erythema and pain)…
- Trial name
- NCT01301677
- Testing
- Hydrocortisone, 2PX+, 2PX-
- Where
- 2 sites in Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- X-pert Med GmbH
Chronic Non-specific Low Back Pain
Prevalence Of Disability And Fear Avoidance Beliefs
Three hundred eighty -one egyptian physical therapists of both genders with age 25-55 years old in Cairo governorate who have worked for at least two years.The study will be conducted to investigate the prevalence of disability…
- Trial name
- NCT07286630
- Testing
- Fear avoidance beliefs questionnaire
- Where
- Egypt
- Volunteers
- 381 people
- Sponsor
- Dina Abdelhady Hammad Attia Ahmed
Low Back Pain
Flares of Low Back Pain With Activity Research Study
Low back pain (LBP) is the most common cause of disability worldwide. Although general activity is encouraged in the treatment of LBP, there is limited empirical information available on the specific types of activities that are…
- Trial name
- FLAReS (NCT04828330)
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- VA Office of Research and Development
Chronic Migraine
Assessment of LBR-101 In Chronic Migraine
The purpose of the study is to determine whether monthly subcutaneous administration of LBR-101 (fremanezumab) is safe and provides migraine prevention in patients with chronic migraine.
- Trial name
- NCT02021773
- Testing
- LBR-101 High Dose, LBR-101 Low Dose
- Where
- 57 sites in United States
- Volunteers
- 264 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Respiratory Depression
Single Dose Crossover Study to Compare the Respiratory Drive After Administration of Belbuca, Oxycodone and Placebo.
The purpose of this study is to explore and compare VRH after administration of Belbuca, Oxycodone HCl and Placebo in recreational opioid users.
- Trial name
- NCT03996694
- Testing
- Belbuca 300 µg, Belbuca 600 µg, Belbuca 900 µg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- BioDelivery Sciences International
Osteoarthritis
Effects of Transcutaneous Electrical Nerve Stimulation on Pain and Disability in Patients With Osteoarthritis
The purpose of this study is to determine the effects of transcutaneous electrical nerve stimulation (TENS) on pain and mobility by comparing different stimulation sitesP: 1. the location with the lowest resistance 2.
- Trial name
- NCT01137266
- Testing
- TENS
- Where
- Netherlands
- Volunteers
- 72 people
- Sponsor
- Maxima Medical Center
Morton's Neuroma
Study to Evaluate the Safety and Tolerability of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
The purpose of this study is to confirm that the local anesthetic applied to subjects with Morton's Neuroma satisfactorily mitigates procedure pain and ensures that post-procedure discomfort or pain will not result in bias or…
- Trial name
- NCT02550756
- Testing
- CTNX-4975
- Volunteers
- 11 people
- Sponsor
- Centrexion Therapeutics
Pain Management, Anxiety
Virtual Reality Distraction for Pain and Anxiety in Hemodialysis Patients
1. Assess pain and anxiety levels in hemodialysis patients during arteriovenous fistula needle insertion. 2. Determine the effect of the distraction technique using virtual reality on pain and anxiety levels during arteriovenous…
- Conditions
- Pain Management, Anxiety, Hemodialysis, Virtual Reality
- Trial name
- NCT07334522
- Testing
- Virtual Reality, standard of care
- Where
- 2 sites in Iraq
- Volunteers
- 142 people
- Sponsor
- Karbala University
Pes Planus
Exercises for Pes Planus
Pes planus is a musculoskeletal syndrome in which the medial longitudinal arch (MLA) of the foot is reduced or flattened. It results from a combination of static and dynamic abnormalities.
- Trial name
- NCT07123753
- Testing
- EXERCİSE
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Dental Pain
Study of Diclofenac Capsules to Treat Dental Pain
The purpose of this study is to determine whether Diclofenac Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT00985439
- Testing
- Diclofenac Test (lower dose), Diclofenac Test (upper dose), Celecoxib 400 mg
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Neck Pain
Effects of Thrust Versus Non-Thrust Thoracic Manipulation on Mechanical Neck Pain.
Neck pain ranks as the 4th leading cause of disability, with high prevalence of mechanical neck pain in young population. As high as 30% of %.
- Trial name
- NCT05542875
- Testing
- Thrust Manipulation, Non-Thrust manipulation, Standard Treatment
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad
Pain
A Safety and Efficacy Study of JNS024 Extended Release (ER) in Japanese and Korean Patients With Chronic Malignant Tumor-Related Cancer Pain
The purpose of this study is to evaluate the safety and efficacy of R331333 (referred to as JNS024 Extended-Release (ER) or CG5503) compared with an active comparator (oxycodone Controlled Release (CR)) in Japanese and Korean…
- Trial name
- NCT01165281
- Testing
- Oxycodone CR, R331333 (referred to as JNS024 ER or CG5503)
- Where
- 52 sites in Japan, South Korea
- Volunteers
- 343 people
- Sponsor
- Janssen Research & Development, LLC
Pain
Efficacy And Safety Of Parecoxib 40mg vs. Ketoprofen 100mg In The Management Of Acute Renal Colic
This is a multicenter, randomized, double blind, double dummy, comparative, active-controlled trial designed to assess the analgesic activity and safety of intravenous doses of parecoxib 40 mg relative to intravenous doses of…
- Trial name
- NAP (NCT00553605)
- Testing
- Ketoprofen 100mg, Parecoxib 40mg
- Where
- 17 sites in Brazil, Chile and 4 more
- Volunteers
- 340 people
- Sponsor
- Pfizer
Pelvic Pain, Pelvic Floor; Relaxation
Investigation of Acute Effects of Myofascial Trigger Point Release in Women With Chronic Pelvic Pain
The patients diagnosed with pelvic pain will be included in the study. Orthopedic tests for pelvic pain were performed after routine gynecological examinations.
- Conditions
- Pelvic Pain, Pelvic Floor; Relaxation, Myofascial Trigger Point Pain
- Trial name
- NCT04401566
- Testing
- Internal myofascial release, External myofascial release, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Akdeniz University
Hidradenitis Suppurativa
Battlefield Acupuncture for Pain in Hidradenitis Suppurativa
The investigators will investigate battlefield acupuncture as a treatment for the pain of hidradenitis suppurativa.
- Trial name
- NCT04218422
- Testing
- Battlefield Acupuncture
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Wayne State University
Chronic Pain, Central Sensitisation
The Effect of Griffonia Simplicifolia on Pain Intensity, Central and Peripheral Sensitization, Painmodulation in Healthy Volunteers
This planned study is based on a randomized, placebo-controlled cross-over design. Griffonia simplicifolia contains the serotonin-precursor 5-hydroxytryptophan (5-HTP), an endogenous amino acid.
- Conditions
- Chronic Pain, Central Sensitisation, Peripheral Sensitization, Neuroinflammatory Response
- Trial name
- NCT06893822
- Testing
- Griffonia simplicifolia
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Postoperative Pain, Shoulder Surgery
The Addition of Sufentanil Interscalene Block in Shoulder Surgery
The purpose of this study is to compare the effects and side effects of interscale block performed with Naropin 0.1% cum sufentanil or Naropin 0.1% in shoulder surgery.
- Trial name
- NCT01025102
- Testing
- Naropin 0.1% cum sufentanil
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Bent Gymoese Jorgensen
Adenotonsillectomy, Children
Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients
Postoperative pain after adenoid and tonsil surgery is significant, with approximately 75% of pediatric patients experiencing severe postoperative pain.
- Conditions
- Adenotonsillectomy, Children, Intranasal Administration, Dexmedetomidine
- Trial name
- NCT07479602
- Testing
- Intranasal dexmedetomidine-esketamine
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking University First Hospital
Transurethral Resection of Prostate
Effectiveness of Nalbuphine as an Adjuvant to Subarachnoid Block on Postoperative Analgesia in TURP Surgery
The goal of this clinical trial is to compare pain after surgery in patients undergoing Transurethral Resection of Prostate. The main question it aims to answer are: Intrathecal nalbuphine as an adjuvant to local anesthetic will…
- Trial name
- NCT06153602
- Testing
- Nalbuphine Hydrochloride 10 MG/ML, Sodium Chloride 0.9 % in 5 ML Injection, Bupivacaine Hydrochloride, Spinal
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Chulalongkorn University