Clinical trials: Pain Cancer
Non-Small Cell Lung Cancer
Preoperative Structured Exercise Programme on Patients With Non-Small Cell Lung Cancer
INTRODUCTION: Lung cancer is among the leading cancers, and surgery has a major role in treatment. Patients diagnosed with Non-Small Cell Lung Cancer (NSCLC) who are eligible for surgical treatment have a high risk of…
- Trial name
- READY-LUNG (NCT07401056)
- Testing
- Prehabilitation (Structured Preoperative Exercise Programme)
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Hacettepe University
Pain, Chronic, Breast Cancer
Optimizing Psychological Treatment for Pain After Breast Cancer: A Pilot Study
The present study is a pilot study that aims to evaluate the feasibility, validity, and preliminary efficacy of three psychological treatment components for pain after breast cancer, which will be evaluated in a larger trial…
- Trial name
- NCT04841928
- Testing
- Mindful attention, Decentering, Value-based action
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- University of Aarhus
Nausea Post Chemotherapy, Vomiting
Pharmacokinetic and Pharmacodynamic Evaluation of Formulations of Δ9-THC
Study based on the pharmacokinetic, pharmacodynamic, safety and stability evaluation of 3 standardized formulations of THC, to be used in healthy volunteers and post-chemotherapy patients as an adjuvant in the symptomatic…
- Conditions
- Nausea Post Chemotherapy, Vomiting, Cancer Pain, Cancer Related Pain
- Trial name
- NCT05272865
- Testing
- Pharmacokinetic and pharmacodynamic profile of THC oral formulations with Dronabinol as comparator
- Where
- Colombia
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- LaSanta S A S
Breast Cancer, Mastectomy
Effect of Patient-Anesthesiologist Gender Concordance and Analgesia Method on Postoperative Pain in Mastectomy Patients
This prospective observational study aims to evaluate the effect of anesthesiologist gender and patient-anesthesiologist gender concordance, as well as the analgesia method, on postoperative pain levels and analgesic requirements…
- Conditions
- Breast Cancer, Mastectomy, Postoperative Pain, Analgesic Use
- Trial name
- NCT07035275
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Cancer, Chronic Neuropathic Pain
Efficacy of Repetitive Transcranial Magnetic Stimulation Over the Primary Cortex in Patients With Neuropathic Pain and Cancer
High-frequency repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex (M1) has shown its efficacy to alleviate pain in patients suffering from refractory neuropathic pain.
- Trial name
- NeuroCanPain (NCT07187219)
- Testing
- Repetitive transcranial magnetic stimulation (rTMS) - active, Repetitive transcranial magnetic stimulation (rTMS) - inactive
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Uterine Myoma, Uterine Adenomyosis
Single Incision Laparoscopic Surgery (SILS) Versus Conventional Laparoscopic Hysterectomy
Multi-center prospective randomized trial of single port laparoscopic surgery (SILS) versus conventional 3-4 ports laparoscopic hysterectomy.
- Trial name
- NCT01483417
- Testing
- Single incision Laparoscopic hysterectomy, Conventional laparoscopic hysterectomy
- Where
- 8 sites in South Korea
- Volunteers
- 240 people
- Sponsor
- Samsung Medical Center
Pediatric Cancer, Procedural Anxiety
Impact of Virtual Reality on Peri-interventional Pain, Anxiety and Distress in a Pediatric Oncology Outpatient Clinic
Pain and anxiety-inducing interventions have a major impact on pediatric patients. Pain reduction by virtual reality (VR) during port and vein punctures is well studied.
- Conditions
- Pediatric Cancer, Procedural Anxiety, Procedural Pain
- Trial name
- NCT06235723
- Testing
- Virtual Reality
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Hannover Medical School
Breast Neoplasms, Pain,Postoperative
Chlorhydrate of Ropivacaine and Breast Cancer Surgery
The aim of the study is to evaluate the effect of local anesthetic (chlorhydrate of ropivacaine) to prevent chronic pain after breast surgery for cancer.
- Trial name
- NCT00370240
- Testing
- Chlorhydrate de Ropivacaine
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Institut Curie
Cancer Patients With Cancer Pain
DECLIC Patient Education Program : Assessment Through a Population Health Intervention Research Approach (LE DECLIC EPRI)
Cancer pain is a frequent symptom, reported by 20 to 70% of patients in any stage of the cancer disease : 60 to 70% in the advanced stage of the disease and 20 to 40% among the survivors.
- Trial name
- NCT04634097
- Testing
- Experimental group, standrad group
- Where
- 5 sites in France
- Volunteers
- 246 people
- Sponsor
- Institut Curie
Breast Cancer, Pain
Pilot Study to Evaluate the Effect of Aromatase Inhibitor Therapy on Pain Threshold in Breast Cancer Patients
Postmenopausal women who have hormone receptor positive breast cancer are typically treated with aromatase inhibitor medications, which substantially decrease the amount of estrogen produced by their bodies.
- Conditions
- Breast Cancer, Pain, Arthralgia
- Trial name
- NCT01814397
- Testing
- Anastrozole, exemestane, letrozole
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan Rogel Cancer Center
Breast Cancer Surgery Pain
The Effect of Nerve Blocks on Analgesia in Breast Cancer Surgery
Postoperative pain following modified radical mastectomy remains a significant clinical concern and may adversely affect patient recovery, opioid consumption, and overall patient satisfaction.
- Trial name
- breast surgery (NCT07601490)
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Serratus anterior plane block (SAP)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Therapeutic Touch, Cancer
Reiki for Cancer: Pain, Anxiety, and Stress
The goal of this clinical trial is to investigate the effects of Reiki, Sham Reiki, and Progressive Relaxation Exercise on the levels of pain, anxiety, and stress in cancer patients.
- Trial name
- NCT06296680
- Testing
- Reiki, Progressive Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Ege University
Interviews
Impact of a Pharmaceutical Interview at the Initiation of Opioid Treatment for Acute Non-cancer Pain
In adult emergency departments, the number of admissions for adverse effects related to opioid use is constantly increasing. However, the massive flow of patients, lack of time, and rapid rotation of physicians in this department…
- Trial name
- OPI-HOME (NCT07049796)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Rouen
Pain, Pain Management
The Effect of Music During Colonoscopy
Colonoscopy is an important examination used to diagnose conditions such as inflammatory bowel disease and colorectal cancer and plays a central role in colorectal cancer screening programs.
- Trial name
- NCT07454993
- Testing
- Music intervention
- Where
- Denmark
- Volunteers
- 1,042 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Pain, Analgesics, Opioid
Safety and Tolerability of Long-Term Administration of Hydromorphone HCI CR (Controlled Release)
The purpose of study was to characterize the safety and tolerability of long-term repeated dosing of OROS hydromorphone controlled release tablets (8,16,32, and 64 mg) in patients with chronic cancer pain or chronic non-malignant…
- Trial name
- NCT00410748
- Testing
- OROS hydromorphone HCI CR
- Volunteers
- 388 people
- Sponsor
- Alza Corporation, DE, USA
Cancer Pains
Change the Dose Frequency of Controlled-Release Oxycodone to Refractory Pain
Many patients with cancer experience moderate to severe pain that requires treatment with strong opioids, of which oxycodone and morphine are examples, they are widely applied in clinical treatment because of sustained-released…
- Trial name
- NCT03639415
- Testing
- Increasing the Controlled-Release Oxycodone dose frequency
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fujian Cancer Hospital
Prostate Cancer Surgery
Spinal Anesthesia for Robotic Assisted Laparoscopic Prostatectomy
The investigators hypothesised that spinal anesthesia as an adjunct to general anesthesia would facilitate faster recovery and less pain in patients undergoing laparoscopic robotic prostatectomy.
- Trial name
- NCT06860893
- Testing
- Spinal Anesthesia with Bupivacaine
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- University Hospital of North Norway
Childhood Cancers, Pediatric Oncology
Parent-Child Mandala Painting During Chemotherapy
This randomized controlled trial aims to evaluate the effects of a parent-child mandala painting intervention conducted during the chemotherapy process on caregiver burden, psychological well-being, and child fear and pain levels…
- Trial name
- NCT07363005
- Testing
- Parent-Child Mandala Painting Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Yuzuncu Yil University
Prostate Cancer
Postoperative Patient Comfort and Quality of Micturition in Suprapubic Tube vs. Transurethral Catheterization After RARP
The purpose of the study is to determine, whether the postoperative quality of micturition and continence can be improved depending on the urinary drainage catheter and retention after robot assisted radical prostatectomy.
- Trial name
- MPH (NCT02812173)
- Testing
- suprapubic tube ex 2 day, suprapubic tube ex 5 day, transurethral catheter ex 5 day
- Where
- Germany
- Volunteers
- 234 people
- Sponsor
- St. Antonius Hospital Gronau
Colon Cancer, Colon Diverticulosis
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery…
- Conditions
- Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis
- Trial name
- NCT02958566
- Testing
- Acetaminophen, Gabapentin, Orphenadrine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Illinois College of Medicine at Peoria