Clinical trials: Pain Assessment
Analgesia
To Evaluate the Efficacy and Safety of Tegileridine and Oliceridine Injections in the Treatment of Postoperative Pain
This was a single-center, randomized, open-label, controlled exploratory study conducted in Chinese patients. The study planned to enroll Chinese patients to evaluate the efficacy and safety of tegileridine and oliceridine…
- Trial name
- NCT06458400
- Testing
- Tegileridine, Oliceridine, Morphine
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Yuwei Qiu
Cervical Radiculopathy, Cervical Radicular Pain
Non-organic Signs to Predict Outcomes for Neck Pain
Neck pain is the 4th leading cause of disability in the world, with approximately 50% being neuropathic in nature. Epidural steroid injections (ESI) are one of the most commonly used treatments for cervical radiculopathy.
- Trial name
- NCT04320836
- Testing
- Cervical epidural steroid injection
- Where
- 3 sites in United States, South Korea
- Volunteers
- 78 people
- Sponsor
- Johns Hopkins University
Headache, Migraine
Psychological Assessment and Treatment of Chronic Benign Headache
Subjects with chronic migraine or tension headaches will receive 12 sessions of biofeedback or relaxation training after fulfilling screening, intake interviews, \& psychological testing requirements.
- Conditions
- Headache, Migraine, Tension Headache, Stress Headache
- Trial name
- NCT00018811
- Testing
- Relaxation training & thermal biofeedback, Surface EMG biofeedback
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Postoperative Pain
Depomedrol for Genicular Nerve Block.
This study is designed to test the efficacy of adding Depomedrol a long-acting steroid to bupivacaine for relieving postoperative pain and reducing opioid requirements following total knee replacement surgery.
- Trial name
- NCT05893771
- Testing
- Methylprednisolone Injection, Bupivacaine Hcl 0.5% Inj_#2, normal saline
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Menoufia University
Spine Stiffness, Spine Stability
Changes in Trunk Stability Indicators Following Two Types of Exhausting Physical Activities
In this research project, effects of two sports specific types of fatiguing protocols on trunk muscles and specific trunk stability indicators will be studied.
- Trial name
- TNC-FAT (NCT03529734)
- Testing
- 12 min running, Local strengthening exercises
- Where
- Slovenia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Low Back Pain
Trial-based Economic Evaluation of a Mobile Health Intervention for Individuals With Chronic Non-specific Low Back Pain
The aim of this trial is to assess the effectiveness and cost-effectiveness of a supervised and more personalised mhealth intervention compared with conventional exercise therapy in people with chronic non-specific low back pain.
- Trial name
- eBack (NCT06651099)
- Testing
- mhealth application, Conventional exercise therapy
- Where
- 2 sites in Brazil
- Volunteers
- 146 people
- Sponsor
- University of Brasilia
Shoulder Impingement Syndrome
Effects of Progressive Resistance Training Combined With Traditional Physical Therapy in Patients With Shoulder Impingement Syndrome
A randomized control trial will be done on diagnosed Shoulder impingemnet patients with physical therapy screening in Fauji Foundation Hospital Rawalpindi.
- Trial name
- NCT06079944
- Testing
- Progressive resistance training, Traditional physical therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Foundation University Islamabad
Postoperative Pain
Dose Finding Posterolateral Thoracotomy Study
To review safety and effectiveness of two doses compared to current standard of care.
- Trial name
- NCT00807209
- Testing
- Low Dose SKY0402, High Dose SKY0402, Fentanyl via PCA
- Where
- 5 sites in United States
- Volunteers
- 3 people
- Sponsor
- Pacira Pharmaceuticals, Inc
PMS, Menstrual Cramp
A Randomized Placebo-Controlled Study to Evaluate the Effects of a Gummy and Capsule Supplement on Symptoms of Premenstrual Syndrome
This virtual, randomized, placebo-controlled clinical trial evaluates the effectiveness of a PMS capsule and PMS gummy in alleviating premenstrual syndrome symptoms over 12 weeks.
- Conditions
- PMS, Menstrual Cramp, Mood Change
- Trial name
- NCT06763809
- Testing
- PMS Capsule, PMS Gummy
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Semaine Health
Chronic Pain
Exploring the Link Between Pain and Distress in Adolescent Patients with Chronic Pain
The primary aim is to explore what it is about the experience of chronic pain that may cause emotional distress in some young people but not in others, and how particular individual characteristics, as well as family factors may…
- Trial name
- NCT04261114
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- University of Oxford
Complex Regional Pain Syndrome, Chronic Pain
Spinal Cord Stimulation Versus Nerve Blocks and Physical Therapy
The primary objective of this study is to compare the efficacy of SCS using the Precision implantable neurostimulation device and conventional medical treatment (nerve blocks + physical therapy) in subjects with…
- Conditions
- Complex Regional Pain Syndrome, Chronic Pain, Pain
- Trial name
- NCT00414804
- Testing
- Precision SCS, Nerve Blocks and PT
- Sponsor
- Boston Scientific Corporation
Pain, Dementia
Systematic Pain Assessment in Nursing Home Residents With Advanced Dementia
It is estimated that 45-80 % of nursing home residents have substantial pain at any given time. Residents with impaired cognition have been found to report chronic pain more often, more frequent and more severe, compared to…
- Conditions
- Pain, Dementia, Quality of Life
- Trial name
- NCT02945865
- Testing
- Pain assessment
- Where
- Norway
- Volunteers
- 112 people
- Sponsor
- Oslo Metropolitan University
Methadone Toxicity, Methadone Overdose
Methadone Dose Monitoring With a Remote Medication Monitor
Proof of concept: Pilot Study A Pilot, proof of concept, observational study with a long-term goal to develop a minimally invasive wearable Remote Medication Monitor (RMM) that provides continuous, real-time data on methadone…
- Conditions
- Methadone Toxicity, Methadone Overdose, Pain, Chronic, Drug Metabolism, Poor, CYP2D6-Related
- Trial name
- NCT06837571
- Testing
- Measurement of Methadone in the Interstitial Fluid (ISF) before and after prescribed dose taken ex vivo, Measurement of Methadone in the Interstitial Fluid before and after prescribed dose taken in vivo, ISF Extraction Device 2
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cari Health Inc.
Breast Neoplasms
Upper Limb Function After Breast Cancer Surgery: the Role of Post-operative Physical Therapy Intervention
Surgical treatments can cause late effects influencing activity of daily living, physical activity, and overall health. Late effects include persistent pain reported by 30 - 50% of women that underwent breast operations…
- Trial name
- NCT03389204
- Testing
- PHYSICAL THERAPY
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Assuta Medical Center
Orthopaedic Surgery
Pharmacokinetic, Pharmacodynamic and Pharmacogenetic of Morphine After Surgery
The main objective of this study is to improve our knowledge on the pharmacodynamic, pharmacokinetic, and pharmacogenetic relationships of morphine administered to relief severe postoperative pain.
- Trial name
- NCT00822549
- Testing
- intravenous morphine titration
- Where
- France
- Volunteers
- 438 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Human Abuse Potential
Assessment of Abuse Potential of Cebranopadol in Humans
This study will be conducted to evaluate the abuse potential of single doses of cebranopadol as compared with oxycodone, tramadol and matching placebo in recreational drug users.
- Trial name
- NCT05256108
- Testing
- Oxycodone 40 mg, Tramadol 600 mg, Cebranopadol 600 µg
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Tris Pharma, Inc.
Radiculopathy, Neck Pain
The Value of Traction in the Treatment of Cervical Radiculopathy
The purpose of this study is to determine the effectiveness of adding mechanical traction to standard physical therapy treatments for patients with neck and arm pain.
- Conditions
- Radiculopathy, Neck Pain, Spinal Diseases, Musculoskeletal Diseases
- Trial name
- NCT00979108
- Testing
- Physical therapy rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 86 people
- Sponsor
- Intermountain Health Care, Inc.
Post-operative Pain
QSPainRelief-patientCNS : Clinical Biomarkers of Nociception, Sedation and Cognition
QSPainRelief-patientCNS is a monocentric prospective longitudinal study conducted in patients suffering from disabling post-surgical pain for which the treating physician is about to prescribe a given drug combination for the…
- Trial name
- NCT04742790
- Testing
- Scalp electroencephalography (EEG), Laser-evoked potentials (LEPs), Cognitive auditory-evoked potentials (P300)
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- Université Catholique de Louvain
Post Intensive Care Syndrome (PICS)
Post Intensive Care Accelerometery to Study and Support Recovery Outcomes
The primary purpose of this study is to find out whether a wrist-worn activity monitor can help healthcare professionals understand how people recover after they leave the intensive care unit (ICU), where they were cared for when…
- Trial name
- PICASSO (NCT07466446)
- Where
- 3 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Hallux Valgus
A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain From Bunionectomy Compared With Placebo
The purpose of this study is to evaluate the analgesic efficacy and safety of tapentadol immediate-release (IR [CG5503]) for use in the relief of moderate to severe acute pain, compared with placebo, in adult Taiwanese patients…
- Trial name
- NCT01813890
- Testing
- Tapentadol IR 50 mg, Tapentadol IR 75 mg
- Where
- 3 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Janssen-Cilag International NV