Clinical trials: Pain, Procedural
Neonatal Disorder
Soft Tissue Therapy in Managing Procedural Pain Among Neonates.
Effect of Soft tissue Therapy in managing Procedural Pain among neonates admitted in neonatal intensive care unit. This study focuses on the Procedural pain management with the help of Soft tissue manipulation which includes…
- Trial name
- NCT04309162
- Testing
- Soft tissue therapy
- Where
- India
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Forearm Fracture, Radius Fractures
Pain Palliation in Forearm Fractures in the Emergency Department
The aim is to evaluate the success of reduction procedures and pain palliation in patients with forearm fractures undergoing reduction under procedural sedation-analgesia (PSA) and ultrasound (US)-guided infraclavicular nerve…
- Conditions
- Forearm Fracture, Radius Fractures, Ulnar Fracture
- Trial name
- NCT06588907
- Testing
- Bupivacaine Hydrochloride, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Ankara Etlik City Hospital
Procedural Pain, Vaccination Pain
Cold Spray and Helfer Skin Tap for Pain During Infant Vaccination
This randomized controlled experimental study aims to evaluate the effects of cold spray and the Helfer Skin Tap technique on pain levels during intramuscular pneumococcal conjugate vaccine administration in 12-month-old infants.
- Conditions
- Procedural Pain, Vaccination Pain, Injection Pain
- Trial name
- NCT07779681
- Testing
- Cold spray, Helfer Skin Tap Technique
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hitit University
Tooth Extraction, Dental Anxiety
Comparison of Needle-Free Injection and Conventional Syringe for Tooth Extractions in Children
The goal of this clinical trial is to learn whether a needle-free injection system can make tooth extraction less stressful for children than a conventional dental syringe.
- Conditions
- Tooth Extraction, Dental Anxiety, Procedural Pain, Anesthesia, Dental
- Trial name
- NCT07548892
- Testing
- Needle-Free Jet Injection System, Conventional Syringe Injection
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Procedural Pain, Procedural Anxiety
Nonpharmacological Methods for Children in Procedural Pain
The aim of this study was to determine the effect of the distraction cards, virtual reality and Buzzy® methods on venipuncture pain and anxiety in children aged 7-12 years.
- Trial name
- NCT04421430
- Testing
- Distraction cards, Virtual reality, Buzzy
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Pain, Procedural, Procedural Anxiety
Evaluating the Feasibility of VR for Pediatric Renal Biopsies
The purpose of this study is to assess the use of virtual reality (VR) as an adjunct or alternative to pharmacologic sedation in pediatric patients undergoing renal biopsy.
- Conditions
- Pain, Procedural, Procedural Anxiety, Sedation Complication
- Trial name
- NCT05267704
- Testing
- Oculus Go Virtual Reality Headset
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Wound Care, Pain Intensity
Pain Medicine for Wound Care Procedures
This is a randomized double-blind study to determine if the administration of a small-dose of ketamine (an anesthetic)added to morphine (an opioid) contributes to reducing pain intensity during open wound care procedure (WCP)in…
- Conditions
- Wound Care, Pain Intensity, Hyperalgesia, Nausea
- Trial name
- NCT00701909
- Testing
- Morphine plus Ketamine
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Hemorrhoids
Efficacy of Lidocaine Gel Enema After Endoscopic Hemorrhoid Band Ligation for Relief of Post Procedural Pain
This is a prospective study to assess the utility of Lidocaine Hydrochloride 2% gel enema (Hi-Tech Pharmacal Co., Inc.) in reducing post-procedural pain after endoscopic band ligation of internal hemorrhoids.
- Trial name
- NCT03797703
- Testing
- Lidocaine Hydrochloride 2% gel enema
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Facial Wrinkles
A Study to Compare Subject Comfort During and After Injections With the Study Products and the Safety of the Non-FDA Approved Product for the Correction of Nasolabial Folds (NLFs)
The purpose of this research study is to compare subject comfort during and after injection with NADGL and Captique® Injectable Gel, in the nasolabial folds.
- Trial name
- NCT00417469
- Testing
- NADGL
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Genzyme, a Sanofi Company
Procedural Pain, Anxiety
Effect of Stress Ball Use on Pain, Anxiety, and Vital Signs During Ultrasound-Guided Tru-cut Biopsy
This randomized controlled trial aims to evaluate the effect of stress ball application on pain, anxiety, and vital signs in adult patients undergoing ultrasound-guided tru-cut biopsy procedures.
- Conditions
- Procedural Pain, Anxiety, Tru-Cut Biopsy, Stress Response
- Trial name
- STRESS-BX (NCT07613736)
- Testing
- Behavioral: Stress Ball Application
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people
- Sponsor
- Istanbul University
Child, Pain Due to Certain Specified Procedures
External Cold and Vibration Stimulation (Buzzy®) for Procedural Pain Management in Children Undergoing Needle-Related Procedures
Since the late 1980s, several studies focused on pediatric procedural pain and show that it still underevaluated and undertreated, especially in the Emergency Department (ED).
- Trial name
- NCT02616419
- Testing
- Buzzy® device, Maxilene® (Lidocaine liposomal 4%)
- Where
- Canada
- Volunteers
- 354 people
- Sponsor
- St. Justine's Hospital
Joint Dislocation, Perianal Abscess
Adjunctive Nitrous Oxide During Emergency Department Propofol Sedation in Adults
The purpose of this study is to describe the safety and efficacy of nitrous oxide administration for pain and anxiety before propofol in patients requiring any procedure under sedation in the Emergency Department.
- Conditions
- Joint Dislocation, Perianal Abscess, Abscess
- Trial name
- NCT02410707
- Testing
- Nitrous Oxide arm, Propofol, Oxygen
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Albert Einstein Healthcare Network
Infertility
Virtual Reality for Pain and Anxiety During HyFoSy
This randomized controlled study will evaluate whether virtual reality (VR) reduces procedural pain and anxiety in women undergoing hysterosalpingo-foam sonography (HyFoSy), a minimally invasive ultrasound-based procedure used to…
- Trial name
- NCT07816393
- Testing
- virtual reality, rest
- Where
- Israel
- Volunteers
- 68 people
- Sponsor
- HaEmek Medical Center, Israel
Procedural Pain, Acute Pain
Do Vacutainers With Animal Characters Reduce Fear and Anxiety?
The study was designed as a randomized controlled experimental research with the purpose of determining the effect of distraction by using vacutainers of three different animal characters.
- Conditions
- Procedural Pain, Acute Pain, Fear, Anxiety
- Trial name
- NCT06345911
- Testing
- Experimental group
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Procedural Pain
Pharmacogenetics of Ketamine in Children
The need to treat the children with painful diagnostic-therapeutic procedures has increased in the last years. There is evidence from a wide scientific literature that drugs available in the setting of procedural sedation and…
- Trial name
- NCT05796232
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- IRCCS Burlo Garofolo
Child, Procedural Anxiety
Nonpharmacological Methods for Children
The study was designed as a randomized controlled experimental research with the purpose of determining the effect of the methods of cold application and Shotblocker on the pain and anxiety level of the children in reducing the…
- Conditions
- Child, Procedural Anxiety, Procedural Pain
- Trial name
- NCT05070325
- Testing
- Cold application group, Shotblocker group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Procedural Pain
Intravenous Magnesium Sulfate for Post-Endoscopic Symptoms After Upper Gastrointestinal Endoscopy With Biopsy
This randomized placebo-controlled clinical trial evaluated whether intravenous magnesium sulfate reduces esophageal symptoms after upper gastrointestinal endoscopy (UGIE) with biopsy in adult patients.
- Trial name
- NCT07816848
- Testing
- Magnesium sulfate (MgSO4) infusion, 0.9 % sodium chloride
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Hasanuddin University
Critical Illness
The Optimization of Procedural Pain Control in Intensive Care Unit (ICU) Patients
The purpose of this study is to determine the influence of morphine 2,5 mg or morphine 7,5 mg iv during a painful and unavoidable intervention in critically ill patients.
- Trial name
- OPCIC (NCT00558090)
- Testing
- morphine
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- St. Antonius Hospital
Abortion, Second Trimester, Procedural Pain
Cervical Preparation for Same-Day Dilation & Evacuation
This is a noninferiority randomized control trial of two cervical preparation methods prior to same-day Dilation \& Evacuation (D\&E). Cervical preparation is a process that softens and dilates the cervix prior to a procedure.
- Conditions
- Abortion, Second Trimester, Procedural Pain, Procedural Complication
- Trial name
- NCT06799052
- Testing
- Transcervical single-balloon catheter, Synthetic osmotic dilators
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Analgesia Assessment
Bupivacaine Liposome Suspension Administration to Decreasre Peri-procedural Pain in Interventional Radiology (IR) Procedures
This study evaluates the use of liposomal bupivacaine (Exparel), a long-acting local anesthetic, for peri-procedural pain control in patients undergoing interventional radiology (IR) procedures.
- Trial name
- NCT07535411
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital