Clinical trials: Pain, Nociceptive
Visceral Pain
Effect of TEAS Combined With Oxycodone on Postoperative Visceral Pain in Gynecologic Laparoscopic Patients
To investigate the effect and feasibility of percutaneous acupoint stimulation combined with oxycodone on postoperative visceral pain in laparoscopic patients, and provided a clinical basis for optimizing perioperative pain…
- Trial name
- NCT06517069
- Testing
- TEAS, Oxycodone
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Neurologic Pain, Nociceptive Pain
Compounded Pain Creams and Patient Perception
There has been a significant increase in the number of prescriptions being filled for Custom Compounded Pain Creams. This study serves to evaluate the patient perception and satisfaction with this type of pain therapy allowing us…
- Trial name
- NCT02024802
- Where
- United States
- Sponsor
- Marwood LowCost Pharmacy
Low Back Pain, Neck Pain
Prediction of Outcome of Interventional Pain Management
Interventional pain management for back and neck pain is widely used, but the indications and relative merits of these techniques rest subject to discussion.
- Conditions
- Low Back Pain, Neck Pain, Chronic Pain
- Trial name
- POINTPM (NCT02774694)
- Testing
- nociceptive flexion reflex (NFR) threshold ("Paintracker", Dolosys GmbH, Berlin, Germany)
- Where
- Switzerland
- Volunteers
- 350 people
- Sponsor
- Benno Rehberg-Klug
Irritable Bowel Syndrome
Characterization of Pain Processing Mechanisms in Irritable Bowel Syndrome
The purpose of this study is to provide new information and to determine which kinds of brief, tolerable, experimental pain are affected by the drugs being studied in patients with irritable bowel syndrome, a disease that causes…
- Trial name
- NCT00100425
- Testing
- Viceral Perception Testing
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Catastrophizing Pain, Pain, Somatic
The Association Between Conditioned Pain Modulation and Pain Catastrophizing in Chronic Low Back Pain
This study evaluates the potential association between pain catastrophizing thoughts and the ability to dampen pain via endogenous descending inhibition.
- Conditions
- Catastrophizing Pain, Pain, Somatic, Chronic Low Back Pain
- Trial name
- NCT03644810
- Testing
- PPT measurement, Pain catastrophizing scale, Cold Pressor Test
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Gynecologic Laparoscopic Surgery, Hysterectomy
Impact of Nociceptive-Level (NOL) Intraoperative Guided Analgesia During Gynecological Laparoscopic Surgery Under General Anesthesia
The aim of the present study is to show that the use of the NOL device in addition to the Standard of Care (based on mean arterial blood pressure and heart rate values) to guide the administration of opioids compared to the…
- Conditions
- Gynecologic Laparoscopic Surgery, Hysterectomy, Oophorectomy
- Trial name
- NOLGYN (NCT03776838)
- Testing
- Intravenous Fentanyl guided by SoC+NOL, Intravenous Fentanyl guided by SoC
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Chronic Pain
"MecPain", a New Questionnaire to Assess Chronic Pain Mechanisms.
Validation of a new clinical questionnaire, called 'MecPain', including 12 questions, aimed at better defining the pathophysiological mechanisms of a chronic pain condition.
- Trial name
- MecPain (NCT05713604)
- Where
- 2 sites in France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Grenoble
Neuropathic Pain, Chronic Pain
Translation of the Self Completed-Leeds Assessment of Neuropathic Symptoms and Signs Pain Scale
Neuropathic pain, described as 'pain arising as a direct consequence of a lesion or disease on the somatosensory system', affects up to 3-9.8% of the investigators' population, but is often underdiagnosed and undertreated.
- Conditions
- Neuropathic Pain, Chronic Pain, Nociceptive Pain
- Trial name
- NCT02450565
- Testing
- Questionnaire
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Obese Patients, Bariatric Surgical Pain
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
Regional anesthesia is a technique in which a local anesthetic is injected near a nerve or spinal cord to block sensation, motor stimulation, and pain.
- Conditions
- Obese Patients, Bariatric Surgical Pain, Bariatric Surgery (Sleeve Gastrectomy ), Non-Opioid Pain Management
- Trial name
- NCT07084753
- Testing
- Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- IVO JURISIC
Cancer Pain, Visceral Pain
Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
Patients with digestive tract malignancy often experience severe and unremitting abdominal pain that negatively affects physical, emotional, and social function, as well as health related quality of life (HRQOL).
- Conditions
- Cancer Pain, Visceral Pain, Gastrointestinal Neoplasms, Cancer of Gastrointestinal Tract
- Trial name
- NCT04907643
- Testing
- PICO G2 4k
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Cedars-Sinai Medical Center
Tissue Pain
Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness
This study involves imaging the skin movements of surface tissue on the back. A clinician will perform assessment and intervention procedures manually, using manual and light movements of stretch and compression.
- Trial name
- OptMeasSkin (NCT06390085)
- Testing
- Soft tissue manipulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Dysmenorrhea, Pain
Examining the Role of Improved NSAID Management in Treating Dysmenorrhea and Bladder Pain
The goal of this study is to see if optimized use of naproxen for treatment of dysmenorrhea will improve pain report from baseline.
- Trial name
- NCT03697720
- Testing
- Naproxen
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Endeavor Health
Colonoscopy
Effect of Butorphanol on Colonoscopy for Patients With Postoperative Visceral Pain
The total incidence of abdominal pain after colonoscopy is almost 50%. Butorphanol is a mixed opioid receptor agonist-antagonist, which has strong sedative and analgesic effects.
- Trial name
- NCT04477733
- Testing
- Butorphanol Injection, Saline
- Where
- China
- Volunteers
- 203 people
- Sponsor
- Beijing Tiantan Hospital
Somatic Pain
Investigation of Low-intensity Focused Ultrasound Pressure
Investigating the relationship between input pressure of low-intensity focused ultrasound and an evoked potential in both eeg and fMRI.
- Trial name
- NCT06343883
- Testing
- low-intensity focused ultrasound - low pressure, low-intensity focused ultrasound - medium pressure, low-intensity focused ultrasound - high pressure
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Hypovolemia, Somatic Pain
Influence of Variations of Systemic Venous Return on Analgesia Nociception Index (ANI) During General Anaesthesia
The purpose of this study is to determine whether the value of analgesia nociception index (ANI) is influenced by variations of systemic venous return (cardiac preload) under general anaesthesia.
- Trial name
- NCT02193412
- Testing
- noxious stimulus, change in operating table slope: head-down tilt position, change in operating table slope: head-up tilt position
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille