Clinical trials: Pain, Muscle, open to volunteers
Migraine in Children, Complex Regional Pain Syndromes
Supraspinal Processing of Sensory Aspects of Pain
The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients.
- Conditions
- Migraine in Children, Complex Regional Pain Syndromes, Musculoskeletal Pain, Functional Abdominal Pain Syndrome
- Trial name
- SCP (NCT05814497)
- Testing
- Multisensory Task, Graphesthesia, Divided attention
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Fibromyalgia
Safety and Efficacy of Ketamine Intravenous Infusions in the Treatment of Fibromyalgia
Previous studies of intravenous ketamine, which is a non-competitive N-methyl-D aspartate receptor antagonist, for fibromyalgia pain relief are limited to three studies.
- Trial name
- NCT06916403
- Testing
- Intravenous Ketamine Infusions
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Wilderman Medical Clinic
Chronic Fatigue Syndrome (CFS)
Controlled Trial of Hydrogen Water as a Treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
This is a 16-week controlled treatment trial of an over-the -counter supplement, hydrogen water, for individuals with ME/CFS patients. An active treatment condition will be compared to a placebo-control condition.
- Trial name
- ME/CFS (NCT07753122)
- Testing
- Molecular hydrogen produced by a metallic magnesium tablet, consumed 3x a day dissolved in water. Treatment duration is 16 weeks.
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Fred Friedberg
Fibromyalgia, Fibromyalgia (FM)
The Effect of Fermented Grape Juice Consumption on Fibromyalgia Patients
The goal of this clinical trial is to learn if a traditional grape-based fermented drink called hardaliye helps treat fibromyalgia in adult women.
- Conditions
- Fibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome, Primary
- Trial name
- NCT07403929
- Testing
- Medical Nutrition Therapy (MNT), Hardaliye (200 mL/day)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Low Back Pain, Mechanical, Piriformis Syndrome
Strain-Counterstrain Treatment of Piriformis Pain
The purpose of this investigator-initiated study is to provide an efficient and non-invasive treatment option for pain caused by the piriformis muscle.
- Conditions
- Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
- Trial name
- NCT05023005
- Testing
- Strain-Counterstrain treatment of piriformis muscle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Post-Traumatic Neck Pain, Whiplash-associated Disorders
StressModex for Post-Traumatic Neck Pain
Post-traumatic neck pain is a common consequence of traffic-related and other accidental injuries. While many individuals recover, a subgroup develops persistent pain, disability, and psychological distress.
- Trial name
- StressModex (NCT07824557)
- Testing
- StressModex plus Treatment as Usual
- Where
- 3 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Neck Pain
Effects of MET and Biofeedback Strengthening With and Without Kinesiotaping in Upper Crossed Syndrome
This randomised controlled trial will aim to evaluate the combined effects of Muscle Energy Technique (MET) and biofeedback strengthening, with and without Kinesiotaping (KT), on pain, posture, deep neck flexor strength, and…
- Trial name
- NCT07079319
- Testing
- MET + Biofeedback Strengthening + Kinesiotaping, MET + Biofeedback Strengthening
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Low Back Pain
Psoas Muscle Release in Non-specific Mechanical Low Back Pain
Nonspecific low back pain affects approximately 80% of the population at some point in their lives. The psoas muscle-positioned between the lumbar and pelvic regions-together with the paravertebral muscles, constitutes the…
- Trial name
- NCT06994364
- Testing
- Trigger point release, Simulation of the intestinal listening technique.
- Volunteers
- 40 people
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Low Back Pain, Mechanical, Lower Cross Syndrome
Effects of Post-Isometric Relaxation and Myofascial Release on Low Back Pain With Lower Cross Syndrome
This randomized controlled trial aims to evaluate the combined effects of post-isometric relaxation and myofascial release on pain, flexibility, and functional disability in individuals with low back pain associated with lower…
- Conditions
- Low Back Pain, Mechanical, Lower Cross Syndrome, Hamstring Muscle Tightness
- Trial name
- NCT07496099
- Testing
- post isometric relaxation, MYOFASCIAL RELEASE, Conventional Static Stretching
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Karachi
Cervical Radiculopathy
Gait Asymmetry And Its Relationship With Neck Pain And Muscles Strength In Patients With Cervical Radiculopathy
This study will be conducted to: Investigate the relationship between neck pain severity and bilateral gait symmetry in patients with cervical radiculopathy.
- Trial name
- NCT07326202
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
CHRONIC NON-SPECIFIC NECK PAIN
Instrument-Assisted Soft Tissue Mobilization Versus Muscle Energy Technique on Chronic Non-specific Neck Pain
the aim of this study is to investigate if there is any difference between INSTRUMENT-ASSISTED SOFT TISSUE MOBILIZATION and Muscle Energy Technique over sternocleidomastoid on Neck pain, Range of motion and Functional disability…
- Trial name
- NCT06799130
- Testing
- instrument-assisted soft tissue mobilization, Muscle energy technique
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Well-Being, Psychological, Work Injury
Eastern Principles Acceptance and Commitment Therapy For Injury Prevention Among Nurses and Nursing Aides
This clinical trial will evaluate the effectivness of an Eastern Principles Acceptance and Commitment Therapy intervention (EPACT) relative to an estabished traditional Western-based Acceptance and Commitment Therapy intervention…
- Conditions
- Well-Being, Psychological, Work Injury, Musculoskeletal Pain, High Frequency Heart Rate Variability
- Trial name
- NCT06813495
- Testing
- Eastern Principles Acceptance and Commitment Therapy for Nurses and Nursing Aids (EPACT NNA), Acceptance and Commitment Therapy for Nurses and Nursing Aids (ACT NNA)
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- Bowling Green State University
Lateral Epicondylitis, Tennis Elbow
Wrist Heavy Slow Resistance and Shoulder Stabilization Exercises on Pain, Grip Strength and Functional Ability in Lateral Epicondylitis
The study will compare the shoulder and wrist treatment approaches to determine their effect on elbow. Thirty-two medically stable participants with active shoulder and wrist movements will be enrolled into two groups.
- Trial name
- NCT07576829
- Testing
- Wrist heavy slow resistance exercises, Shoulder stabilization exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- University of Faisalabad
Fibromyalgia, Pregabalin
The Efficacy and Safety of Pregabalin and Crisugabalin in Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters.
- Conditions
- Fibromyalgia, Pregabalin, Pain
- Trial name
- NCT07196657
- Testing
- Pregabalin, Crisugabalin
- Where
- China
- Volunteers
- 1,116 people
- Sponsor
- Beijing Tiantan Hospital
Long COVID, Postural Orthostatic Tachycardia Syndrome
The Long COVID-19 Wearable Device Study
To further characterize Long COVID-19 by collecting data from individuals who already own wearable devices or are provided with a wearable device along with basic and enhanced educational materials to determine if both can…
- Conditions
- Long COVID, Postural Orthostatic Tachycardia Syndrome, Dysautonomia, Myalgic Encephalomyelitis
- Trial name
- NCT05741112
- Testing
- Wearable device
- Where
- United States
- Volunteers
- 100,500 people
- Sponsor
- Scripps Translational Science Institute
Fibromyalgia, Pregabalin
The Efficacy and Safety of Pregabalin Combined With Desvenlafaxine in Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters.
- Conditions
- Fibromyalgia, Pregabalin, Pain
- Trial name
- NCT07171320
- Testing
- Pregabalin, Pregabalin with desvenlafaxine
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Beijing Tiantan Hospital
Low Back Pain, Functional Reach
The Relationship Between Transversus Abdominis Muscle Architecture and Upper Extremity Function in Patients With Chronic Low Back Pain
Core stability is the ability to control the position and movement of the trunk for optimal production, transfer, and control of forces in the upper and lower extremities during functional activities.
- Conditions
- Low Back Pain, Functional Reach, Scapular Dyskinesis, Core Muscles
- Trial name
- NCT07474610
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ilayda Dilan Isik
Exercise-induced Muscle Soreness, Exercise-induced Joint Pain
Effects of Eggshell Membrane and Curcumin Extract Supplementation, Separately or Combined, on Recovery From Intense Exercise
Eggshell membrane and Curcumin supplementation prior to intense exercise may reduce inflammation, muscle and joint pain, and promote recovery.
- Conditions
- Exercise-induced Muscle Soreness, Exercise-induced Joint Pain, Exercise-induced Joint Stiffness, Exercise-induced Cartilage Turnover
- Trial name
- NCT07766720
- Testing
- NEM® brand eggshell membrane powder, curQ+® brand highly absorbable curcumin, NEM® plus curQ+® combination
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ESM Technologies, LLC
Myositis
Investigation of the Validity, Reliability, and Responsiveness of the BETY-BQ in Myositis
Individuals diagnosed with myositis have skin, joint, and visceral organ involvement together with proximal muscle weakness, impaired physical function, sexual function, and quality of life also affect individuals psychosocially.
- Trial name
- BETY-BQ (NCT06587724)
- Testing
- Questionnaire study
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Hacettepe University
Fibromyalgia Syndrome
Auricular Acupuncture for Autonomic Balance and Pain in Fibromyalgia
This longitudinal study evaluates the effects of semi-permanent auricular acupuncture on the Autonomic Nervous System (ANS) activity and pressure pain threshold in adult female patients (aged 35-64) diagnosed with Fibromyalgia…
- Trial name
- NCT07641374
- Testing
- The needles will be applied to specific auricular points: Point Zero, Shen Men, Thalamus, and Master Cerebral Point.
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Italian Association for the Research and the Scientific Update