Clinical trials: Pacemaker
Aortic Aneurysm, Aortic Diseases
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels
As potential biomarkers of pressure-related aortic damage, matrix metalloproteinases (MMP) have been implicated in the pathogenesis of aortic aneurysm because of the important role they play in connective tissue homeostasis.
- Conditions
- Aortic Aneurysm, Aortic Diseases, Pacemaker DDD
- Trial name
- NCT03727542
- Testing
- adjustment of atrioventricular delay in DDD packers
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Diastolic Function, Cardiac Output
Impact of Pacing Mode and Diastolic Function on Cardiac Output
Background It is known from previous research that in patients with complete AV (atrioventricular) block and pacemaker stimulation stroke volume and cardiac output are higher with AV-synchronous than with AV-dyssynchronous…
- Conditions
- Diastolic Function, Cardiac Output, Pacemaker Stimulation Mode, Stroke Volume
- Trial name
- PADIAC (NCT04068233)
- Testing
- Pacemaker stimulation mode
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kepler University Hospital
Anesthesia, Local
Effective Use of Pecs and Transversus Thoracics Plane Blocks for Subcutaneous Cardiac Pacemaker Insertion: A Case Series
Participants that undergo permanent cardiac pacemaker implantation can often present with challenging anesthetic management plans for the anesthesia provider.
- Trial name
- NCT03899701
- Testing
- PEC I and PEC II blocks
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Transcatheter Aortic Valve Implantation, Permanent Pacemaker Implantation
A Multimodal Strategy to Screen for and Rule-Out Delayed High-Grade Conduction Disturbances After TAVR
Electrocardiogram (ECG)-based algorithms have been proposed to guide post-TAVI conduction management; however, their ability to predict clinically relevant delayed conduction disturbances remains limited.
- Conditions
- Transcatheter Aortic Valve Implantation, Permanent Pacemaker Implantation, Right Bundle-Branch Block, Left Bundle-Branch Block
- Trial name
- LATETAVI (NCT07414485)
- Testing
- retrospective health data collection
- Where
- France
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Fibrosis, Atrial Fibrillation
Myocardial Fibrosis in Patients With Permanent Pacemakers
Patients with cardiac pathology and arrhythmias including those who have indications for pacemakers implantation will be included in the study.
- Conditions
- Fibrosis, Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT05920226
- Testing
- pacemakers implantation and assessment of cardiac function and cardiac fibrosis, assessment of cardiac function and cardiac fibrosis
- Where
- Russia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ryazan State Medical University
Cardiac Pacemaker, Cardiac Rhythm Disorder
AVEIR Remote Care System Non-Significant Risk Study
The goal of the study is to understand the performance of the AVEIR Remote Care System in an initial patient cohort which will inform the ability to offer a remote follow-up solution to all patients implanted with Aveir LP…
- Conditions
- Cardiac Pacemaker, Cardiac Rhythm Disorder, Bradycardia
- Trial name
- NCT06542133
- Testing
- AVEIR remote care system
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Pacemaker DDD
Right Ventricular Septal Versus Apical Pacing: Echocardiographic Study
This study aims to compare the effect right ventricular apical versus septal pacing on left ventricular function by deformation imaging using 2D speckle tracking echocardiography.
- Trial name
- NCT06045143
- Testing
- Patients undergoing DDD pacemaker implantation
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cardiovascular Disease
St. Mary's Duluth Clinic (SMDC) Pacemaker Magnetic Resonance Imaging (MRI) Study
The purpose of this study is to monitor and follow non-pacemaker dependent patients with implanted permanent pacemakers, who undergo medically required Magnetic Resonance Imaging (MRI) scans.
- Trial name
- NCT00631904
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Essentia Health
Pacemaker Complication, Congestive Heart Failure
Optimised Pacing Program
Permanent pacemakers are a common treatment for slow heart beats. In the UK 300,000 people have a pacemaker, and each year another 36,000 receive them. All of these patients are usually seen yearly to have their device checked.
- Trial name
- OPT-pace (NCT01819662)
- Testing
- Enhanced standard management, Optimised heart failure management, Standard management
- Where
- 3 sites in United Kingdom
- Volunteers
- 1,793 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Educational Activities
The Effect Of Education Given According to Meleıs' Transitional Theory to Patients With Pacemaker
This study will be carried out to determine the effect of training given according to Meleis's Transition Theory to patients with pacemaker implantation on anxiety, depression and self-efficacy levels.
- Trial name
- NCT06204601
- Testing
- Education According to Meleis' Transitional Theory to Patients With Pacemaker
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ordu University
Heart Failure
Implant of the WiSE CRT System With an Intracardiac Pacemaker
This study is a single arm, prospective, feasibility, multi-centre, observational study. Participants will be suitable for a Cardiac Resynchronisation Therapy (CRT) implant using Wireless Stimulation Endocardially for Cardiac…
- Trial name
- TLC (NCT05451797)
- Testing
- Implant of WiSE-CRT with intracardiac pacemaker
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Bradycardia, Atrial Tachyarrhythmia
Evaluating the Electro Magnetic Interference of Using Tablet and Smart Phone on Leadless Pacemaker (MICRA)
The purpose of this study is to evaluate the effects that electromagnetic field exposure from using a tablet and smart phone have on a leadless pacemaker (MICRA device).
- Trial name
- MICRA (NCT02758210)
- Testing
- Use of a Tablet, Use of a Smart Phone
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emory University
Aortic Stenosis, Disorder of Prosthetic Cardiac Valve
Biomarkers in Aortic Stenosis - B.A.S.S.
This study is being done to determine whether or not new blood test(s) can determine the severity of heart conditions. Aortic stenosis, hypertrophic cardiomyopathy, mitral regurgitation, aortic regurgitation, artificial heart…
- Conditions
- Aortic Stenosis, Disorder of Prosthetic Cardiac Valve, Aortic Valve Insufficiency, Mitral Valve Insufficiency
- Trial name
- BASS (NCT01334801)
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Shoulder Dislocation
Throwing Velocity and Patient Reported Outcomes in Elite Level Handball Players After Completion of Shoulder-Pacemaker Strength Training
The successful application of treatment protocols using motion-triggered neuromuscular electrical stimulation (NMES) for treatment-resistant functional posterior shoulder instability was recently demonstrated.
- Trial name
- NCT06459258
- Testing
- Motion-triggered NMES training protocol, Non-Motion-triggered NMES training protocol
- Where
- Austria
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sportorthopädie Zentrum in Wien Hietzing
Pacemaker, Artificial
A Pilot Study on Pacemaker Interference From Peripheral Nerve Stimulator for Regional Anesthesia
In this prospective pilot study, we proposed to evaluate the effects of left interscalene stimulation on cardiac pacemaker function.
- Trial name
- NCT00586248
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Atrial Fibrillation, Hypertension
Irbesartan for the Prevention of Atrial Arrhythmias and Cardiac Electrical Remodeling in Patients With Hypertension and Permanent Pacemakers
The purpose of this study is to determine whether irbesartan will reduce the rate of recurrent atrial high rate episodes and the development of clinical sustained atrial fibrillation in patients with hypertension and permanent…
- Trial name
- NCT00225667
- Testing
- Irbesartan
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Connolly, Stuart, M.D.
Pacemaker Electrode Lead Fracture, ICD
Adverse Events of MRI With Abandoned Leads
The purpose of this study is to determine the safety and efficacy of MRI scanning in patients with fractured or abandoned endocardial leads.
- Trial name
- NCT04478773
- Testing
- MRI
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Lancaster General Hospital
Cardiac Pacemaker, Artificial
Clinical Investigation Plan for the AVOPT Data Collection Clinical Study
The purpose of this study is to collect clinical data for the development and evaluation of a new device feature for automatic AV-delay (AVD) optimization.
- Trial name
- NCT03049722
- Testing
- Pacemaker
- Where
- 2 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biotronik Canada Inc
Pacemaker, Physical Activity
Evaluation of Physical Fitness and Physical Activity Levels of Pediatric Arrhythmia Patients With Pacemaker
The aim of this study was to evaluate physical fitness and physical activity levels of pediatric arrhythmia patients with pacemaker compared with their healthy peers.
- Trial name
- NCT03847298
- Testing
- Physical activity and physical fitness assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Disorder of Cardiac Pacemaker System
Evaluation Of Pacemakers in Children
Pacemakers were introduced into clinical practice several decades ago and currently are used in a growing number of patients. Since insertion of the first cardiac Pacemaker in 1958, vast changes have occurred in both the…
- Trial name
- NCT04163770
- Testing
- caliberation of pacemaker
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University