Clinical trials: PTSD
Post Traumatic Stress Disorder, Traumatic Brain Injury
Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation
This study will test the clinical efficacy of an accelerated TMS (accel-TMS) protocol that rapidly addresses PTSD symptoms with 1 week (25 sessions over 5 days) of condensed treatment.
- Trial name
- NCT06544408
- Testing
- Cool B70 AP Coil - Active (dl-PFC), Cool D-B80 AP Coil - Active (dm-PFC), Cool B70 Treatment Coil - Active Only
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Florida State University
Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder
Empowering Perinatal Adolescents Through Writing
This is a feasibility and acceptability study of Written Exposure Therapy (WET) for PTSD in pregnant and postpartum adolescents and youth with PTSD.
- Conditions
- Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder, PTSD and Trauma-related Symptoms, Pregnancy and PTSD
- Trial name
- EMPWR (NCT06771817)
- Testing
- Written Exposure Therapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Texas Southwestern Medical Center
Posttraumatic Stress Disorders
PTSD Symptom Reduction by Propranolol Given After Trauma Memory Activation
This study is a randomized, double-blind, placebo-controlled clinical trial of propranolol combined with trauma memory reactivation, to determination if this approach is effective in treating PTSD symptoms.
- Trial name
- NCT00645450
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
PTSD
Efficacy of Cervical Sympathetic Blocks for PTSD
Millions of people suffer from anxiety disorders, including posttraumatic stress disorder (PTSD)-a condition that can profoundly disrupt daily life.
- Trial name
- NCT07087015
- Testing
- Cervical sympathetic nerve block, Ropivacaine, Normal Saline
- Volunteers
- 20 people
- Sponsor
- Stanford University
PTSD - Post Traumatic Stress Disorder
First-Line Intervention for PTSD - Intensive Treatment
The goal of this clinical trial is to learn if an intensive program can treat post-traumatic stress disorder (PTSD) in adults getting treatment for the first time, and whether it has lower societal costs.
- Trial name
- FLIP-IT (NCT06700590)
- Testing
- Intensive Treatment, Treatment as usual
- Where
- 4 sites in Netherlands
- Volunteers
- 186 people
- Sponsor
- ARQ National Psychotrauma Centre
Single-ventricle, Posttraumatic Stress Disorder
The PaTHS Descriptive Correlational Longitudinal Study
The primary objective of this study is to measure parent's post-traumatic stress before and after their infant's second palliative heart surgery for single ventricle congenital heart disease.
- Conditions
- Single-ventricle, Posttraumatic Stress Disorder, Psychosocial Impairment
- Trial name
- PaTHS (NCT04785482)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Children's Mercy Hospital Kansas City
Post-traumatic Stress Disorder
Effectiveness of a Brief Intensive Trauma Treatment for Adolescents With (s)PTSD: a Multi-center RCT
The primary objective of this study is to examine the effectiveness of a Brief Intensive Trauma Treatment (BITT) for adolescents with (s)PTSD.
- Trial name
- NCT06143982
- Testing
- Brief Intensive Trauma Treatment
- Where
- 3 sites in Bonaire, Saint Eustatius and Saba , Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
PTSD
Cognitive-behavioral Therapy for Treatment of Post-traumatic Stress Disorder and Related Problems
The purpose of this study is to evaluate the efficacy of a form of cognitive behavioral therapy (CBT) in a population of individuals with PTSD and common related problems (depression, anxiety or sleep disorders, pain…
- Trial name
- CBT-PTSD-RP (NCT03019497)
- Testing
- Specific Modules, Cognitive behavioral therapy
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Université de Montréal
Chronic Pain, Acute Pain Due to Trauma
The Mobile PTSD Coach App in Acute Injury Survivors
This project is a preliminary randomized controlled trial testing the potential impact of the PTSD Coach mobile application at reducing posttraumatic stress and pain symptoms among acutely injured trauma patients.
- Conditions
- Chronic Pain, Acute Pain Due to Trauma, Posttraumatic Stress Disorder
- Trial name
- NCT03247179
- Testing
- PTSD Coach mobile application
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- University of Pittsburgh
Fibromyalgia, PTSD
Group Therapy for Fibromyalgia:the Effectiveness of Mindfulness -Based VS Cognitive-behavioral Therapy
This study was conducted as part of a collaboration between the Maccabi Health Fund and Bar Ilan University. Fibromyalgia is a chronic pain disorder, highly co-morbid with depression, stress, and anxiety.
- Conditions
- Fibromyalgia, PTSD, Depression, Stress
- Trial name
- NCT04265196
- Testing
- cognitive behavioral group therapy, Mindfulness-based group therapy
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Bar-Ilan University, Israel
Posttraumatic Stress Disorder
Intervention Evaluation WEH (Women Who Have Experienced Homelessness)
Homelessness and associated traumas disproportionately impact women relative to men. Women who have experienced homelessness (WEH) universally face traumatic stress, often before becoming homeless and while experiencing…
- Trial name
- NCT06570525
- Testing
- NurseNET, PAL
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
PTSD, Traumatic Brain Injury
Psychological Treatment for Children Suffering From Post Traumatic Stress Symptoms and Mild Traumatic Brain Injury
The purpose of this study is to determine whether Prolonged Exposure Therapy (PE)is effective in the treatment of post-traumatic stress symptoms in children and adolescents with mild traumatic brain injury (m-TBI) due to motor…
- Conditions
- PTSD, Traumatic Brain Injury, Post Concussive Syndrome
- Trial name
- TBI (NCT01315379)
- Testing
- Prolonged Exposure Therapy
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Complex Post-Traumatic Stress Disorder
A Pilot Study of a Trauma-Sensitive Mindfulness and Compassion Intervention
This mixed-methods pilot study aim to assess the changes in symptoms of post-traumatic stress disorder (PTSD), complex post-traumatic stress disorder (CPTSD), dissociative symptoms, self-critique, and self-compassion following…
- Trial name
- NCT05993468
- Testing
- TMC Treatment Approach
- Where
- Norway
- Volunteers
- 17 people
- Sponsor
- Modum Bad
PTSD
Safety and Efficacy of Cannabidiol (CBD) for Symptoms of PTSD in Adults
Post-traumatic stress disorder (PTSD) is a psychiatric disorder than may develop following a traumatic event including serious incidents, natural or human-caused disasters, violence, death of a loved one, receipt of traumatic…
- Trial name
- NCT05269459
- Testing
- Cannabidiol Administered as Nantheia ATL5
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Nebraska
Posttraumatic Stress Disorder, Intrusive Traumatic Memories
Tackling Intrusive Traumatic Memories After a Difficult Birth
This proof-of-principle study aims to investigate the effects of a brief behavioural procedure including a computerized visuospatial task (the computer game "Tetris") preceded by a reactivation of the traumatic memory of…
- Trial name
- NCT04286724
- Testing
- Brief behavioural procedure including a computerized visuospatial task (computer game "Tetris")
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Antje Horsch
Post Traumatic Stress Disorder
Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSD
This will be a 12-week, multicenter, randomized, double-blind trial evaluating the efficacy, safety, and tolerability of brexpiprazole + sertraline combination treatment in adult participants with Post-Traumatic Stress Disorder.
- Trial name
- NCT04124614
- Testing
- Brexpiprazole, Sertraline
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Post Traumatic Stress Disorder, Anxiety
Level and Predictors of Trauma-symptoms Among Health Workers and Public Service Providers During the COVID-19 Outbreak
The aim of this study is to investigate the levels of trauma and mental symptoms (i.e., depression and anxiety) among health workers and public service providers during the strict social distancing government-initiated…
- Conditions
- Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT04374097
- Where
- Norway
- Volunteers
- 1,778 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Insomnia, Posttraumatic Stress Disorder (PTSD)
Testing the Insomnia Coach Mobile App With Veterans With Insomnia and PTSD
The objective of this randomized controlled trial of the Insomnia Coach mobile app is to evaluate the potential effects of app use on reducing insomnia symptoms among Veterans with significant insomnia and PTSD symptoms.
- Trial name
- NCT07083869
- Testing
- Insomnia Coach, Sleep Well
- Volunteers
- 130 people
- Sponsor
- VA Palo Alto Health Care System
Insomnia, Posttraumatic Stress Disorder
An Evaluation of Insomnia Treatment to Reduce Cardiovascular Risk in Patients With Posttraumatic Stress Disorder
Posttraumatic stress disorder (PTSD) is a chronic, debilitating psychiatric disorder that is associated with an increased risk of death due to cardiovascular disease (CVD). Most individuals with PTSD also have Insomnia Disorder.
- Conditions
- Insomnia, Posttraumatic Stress Disorder, Cardiovascular Risk Factor
- Trial name
- NCT04498754
- Testing
- Cognitive Behavior Therapy for Insomnia, Weekly phone contacts
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Duke University
PTSD, Posttraumatic Stress Disorder
Biomarkers in the Retina for Prognosticating Mental Health Treatments
Title: ERG as a potential biomarker of SSRI-responsive PTSD: A pilot study Posttraumatic stress disorder (PTSD) affects many individuals who experience a traumatic event.
- Trial name
- BRIGHT (NCT06363968)
- Testing
- RETeval
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Puget Sound Health Care System