Clinical trials: PTSD
Posttraumatic Stress Disorder, Alcohol Use Disorders
CAP: Doxazosin in the Treatment of Co-Occurring PTSD and Alcohol Use Disorders
The proposed study will examine the efficacy of doxazosin in the treatment of PTSD and alcohol use disorder or substance use disorders.
- Trial name
- Doxazosin (NCT02500602)
- Testing
- doxazosin
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- VA Office of Research and Development
PTSD and Alcohol Use Disorder
Topiramate and Prolonged Exposure
Alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) frequently co-occur, and having both disorders is associated with greater psychological and functional impairment than having either disorder alone.
- Trial name
- TOP (NCT03176953)
- Testing
- topiramate, prolonged exposure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
PTSD
Life With Covid Since 2020: a Randomized Control Trial of a Real-time Data Collection Smartphone-based App Assessing and Treating the Covid-19 Psychological Impacts
The COVID-19 pandemic and more specifically the confinement is an unpleasant experience for those who undergo it. Separation from loved ones, the loss of freedom, uncertainty over disease status, and boredom can, on occasion…
- Trial name
- VieCovid2020 (NCT05054101)
- Testing
- Real-time assessment using the VieCovid2020 smartphone application
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mental Health Issue, Mental Stress
"OnCall": Implementation Study of M-Health for Canadian Public Safety Personnel
First Responders, or Public Safety Personnel (PSP), play a key role in protecting the health and safety of Canadians, yet this important work can take a toll on their mental health, leading to an elevated risk of post-traumatic…
- Conditions
- Mental Health Issue, Mental Stress, Post Traumatic Stress Disorder
- Trial name
- OnCall (NCT05255419)
- Testing
- OnCall mobile health peer support app
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- McMaster University
Trauma, Nervous System
Northwest Therapies Trauma Psilocybin Study Compassionate Use Study
The on-boarding of unregulatable trauma in the United States has reached 20%, which is 1/5 of the population. A population of this magnitude, by definition has now reached an epidemic classification.
- Trial name
- NWTTPS (NCT05042466)
- Testing
- Trauma
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NWTraumatherapies
PTSD
Safety Study of Riluzole to Treat Post-traumatic Stress Disorder (PTSD)
The purpose of this study is to determine whether Riluzole is effective in the augmentation treatment of post-traumatic stress disorder (PTSD) that is experienced by Active Duty military service members and Operation Enduring…
- Trial name
- NCT02155829
- Testing
- Riluzole
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Uniformed Services University of the Health Sciences
Post Traumatic Stress Disorder (PTSD)
Whole Body Hyperthermia & Combat-Related Posttraumatic Stress Disorder (PTSD)
Combat-related post traumatic stress disorder (PTSD) has become an increasingly pressing public health problem in the United States following the overseas wars of the last decade.
- Trial name
- PTSD + WBH (NCT02077972)
- Testing
- High intensity whole-body infrared heating
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Arizona
PTSD
Acceptability and Feasibility of Apollo in Veterans With a History of PTSD
The proposed investigation is an open label pilot study intended to establish the acceptability and feasibility of the Apollo in a population of Veterans. Exploratory data regarding biological signatures will also be collected.
- Trial name
- Apollo PTSD (NCT05019651)
- Testing
- Apollo Wearable System
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Lisa Brenner
Stress Disorders, Post-Traumatic
HIRREM in Military Personnel
The purpose of this study is to evaluate the effects associated with the use of in-office High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM) for participants with symptoms of military-related…
- Trial name
- NCT03230890
- Testing
- HIRREM
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Wake Forest University Health Sciences
Female Genital Mutilation, Sexual Dysfunctions, Psychological
Sexual Health of Women With Genital Mutilation Seen at the Saint-Denis Women's Center
This study looks at the sexual health of women who have experienced female genital mutilation (FGM) and who are receiving care at the Women's Center at Saint-Denis Hospital.
- Conditions
- Female Genital Mutilation, Sexual Dysfunctions, Psychological, Sexual Health, Violence Against Women
- Trial name
- NCT07027696
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Intimate Partner Violence, Depression
MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence
The purpose of this R34 exploratory research proposal is to conduct formative work for a larger randomized controlled trial (RCT) evaluating the effectiveness of the "Mother AdvocateS In the Community (MOSAIC) Plus" intervention…
- Conditions
- Intimate Partner Violence, Depression, Post Traumatic Stress Disorder
- Trial name
- MOSAIC Plus (NCT05106361)
- Testing
- MOSAIC Plus, MOSAIC
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Michigan State University
Needs for Rehabilitation, Adult Attachment Style
The Need for Rehabilitation and the Connection With Attachment Styles Among Patients With Gynaecological Cancer
The purpose of this study is to provide new knowledge about: Integration of rehabilitation in a highly specialized gynaecological department. Development and testing of an individually adapted rehabilitation process.
- Conditions
- Needs for Rehabilitation, Adult Attachment Style, Quality of Life., Depression
- Trial name
- NCT01638741
- Testing
- Rehabilitation goals of patients with gynaecological cancer.
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Kamila Adellund Holt
Severe Trauma, General Anaesthesia
Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome
Patients will be selected after studying clinical records.Patients who had general anesthesia due to an injury related to severe trauma within 6 to 12 months prior to inclusion will be included.
- Trial name
- DIStress-AG (NCT03930966)
- Testing
- PDEQ, PCL-5 and demographic survey
- Where
- France
- Volunteers
- 148 people
- Sponsor
- University Hospital, Brest
Depression, Grief
Iwankapiya-Healing: Historical Trauma Practice and Group IPT for American Indians
This study will pilot an intervention that combines group Interpersonal Psychotherapy (IPT), an empirically-supported treatment, and the Historical Trauma and Unresolved Grief Intervention (HTUG), a Tribal Best Practice for…
- Conditions
- Depression, Grief, PTSD, Interpersonal Relations
- Trial name
- HTUG-IPT (NCT02124694)
- Testing
- HTUG
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of New Mexico
Combat Disorders, Post-traumatic Stress Disorder
Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder
This project represents the first randomized clinical trial of psychotherapy for older veterans with posttraumatic stress disorder (PTSD). It will compare relaxation training (RT) to prolonged exposure therapy (PE).
- Trial name
- NCT00539279
- Testing
- Prolonged Exposure Therapy (PE), Relaxation Training (RT)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- US Department of Veterans Affairs
Post Traumatic Stress Disorder (PTSD)
Targeted Accelerated TMS for Post-Traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a highly prevalent and debilitating condition among veterans and active-duty military personnel, with rates as high as 30% in certain combat-exposed populations.
- Trial name
- TAP (NCT07245641)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Stress Disorders, Post-Traumatic, Sleep Disorders
Imagery Rescripting for Posttraumatic Nightmares in Rural Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF) Veterans With Posttraumatic Stress Disorder (PTSD)
Many service members returning from Iraq and Afghanistan have difficulties adjusting back to civilian life. Research shows that symptoms of posttraumatic stress disorder (PTSD) are particularly high in returning Operation…
- Trial name
- NCT00837382
- Testing
- MEDVAMC Nightmare Treatment, Telepsychiatry Nightmare Treatment
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- US Department of Veterans Affairs
Post-traumatic Stress Disorder
Exercise Training to Improve PTSD Symptoms and Health in Older Veterans
Posttraumatic stress disorder (PTSD) is prevalent among military Veterans and is more than just a psychological condition; PTSD has profound negative impacts on health, function, and quality of life.
- Trial name
- NCT04199182
- Testing
- Exercise Training, Healthy Aging Attention Control (HA-ATC)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic, Acute Stress Disorder
Post-traumatic Stress Injuries Among Paramedics and Emergency Dispatchers
As part of their work, emergency first responders, such as paramedics and emergency medical dispatchers are exposed daily to traumatic events.
- Conditions
- Stress Disorders, Post-Traumatic, Acute Stress Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT04202042
- Testing
- Psychological first aid, Usual organisational intervention
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Posttraumatic Stress Disorders, Chronic Insomnia
Integrated CBT-I and PE on Sleep and PTSD Outcomes (Impact Study)
This study aims to examine whether integrating insomnia and PTSD treatment will enhance sleep, PTSD, and quality of life outcomes.
- Trial name
- NCT02774642
- Testing
- CBTI-PE, Hygiene-PE
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- VA Office of Research and Development