Clinical trials: PJI
Bone and Join Infection (BJI), Periprosthetic Joint Infection (PJI)
Prospective Study of Patients Treated for Bone and Joint Infection (BJI) Due to Staphylococcus Aureus, Aiming at Identifying Biomarkers of Diagnosis Interest in Chronic BJI
There are more than one million (> 40,000 cases per year in France) of osteoarticular infections (OAI) yearly in the world. The number of these infections is constantly increasing due to an increase in life expectancy associated…
- Trial name
- ESPRI-IOAC (NCT04583241)
- Testing
- Constitution of serum bank at D0, Constitution of serum bank during follow-up, ELISA assays of serum markers of bone remodeling at D0
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Hospices Civils de Lyon
PJI, Bone and Joint Infection
Periarticular Penetration of Cefazolin and Clindamycin in Second Stage Revision Arthroplasty of the Hip
To prevent periprosthetic joint infection (PJI), optimal penetration of antibiotics into the joint-space is needed. In revision arthroplasty, the incidence of PJI is increased compared to primary arthroplasty.
- Conditions
- PJI, Bone and Joint Infection, Pharmacokinetics
- Trial name
- CONCENTRATE (NCT05421312)
- Testing
- sampling blood, Sampling synovial fluid, Sampling bone tissue
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Knee Osteoarthritis, PJI
Joint Microbiome Study for the Knee
Prosthetic joint infection (PJI) is a devastating complication following arthroplasty. An utmost effort has been done to clarify risk factors and microbiology of PJI.
- Trial name
- NCT05254145
- Testing
- Next Generation Sequencing
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics