Clinical trials: PFAS
Breast Cancer
Studying The Association Between Environmental Exposure to PFAS and Breast Cancer in Assiut Governorate- Egypt
1. Measuring serum level of PFAS in breast cancer female patients and healthy participants. 2. Studying the correlation between serum level of PFAS and breast cancer risk through statistical modeling and analysis. 3.
- Trial name
- NCT06457282
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assiut University
Environmental Exposure, PFAS Exposure
Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters
This study is designed to evaluate the effect of a probiotic dietary supplement containing Streptococcus salivarius on serum PFAS levels in male firefighters with documented occupational PFAS exposure, following twice-daily use…
- Trial name
- AFCRO202 (NCT07846371)
- Testing
- Streptococcus salivarius 46-SL1
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cambiotics ApS
Healthly Volunteers, Oncologic Disease
A Two-Way Path to Health: Environmental Influences on Skeletal Muscle Endocrine Function
Given the well-established anti-inflammatory and health-promoting effects of physical activity as a non-pharmacological intervention, an important question remains whether different types of exercise differ in their ability to…
- Trial name
- COMPASS (NCT07706465)
- Testing
- Experimental: IWT- Interval Walking Training, Exercise training II, Walking
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Obesity (Disorder)
Role of the Environment in Pediatric Obesity
Childhood obesity is a particular concern in developed countries such as the United States, the United Kingdom, Canada, and certain European countries.
- Trial name
- REOP (NCT07545174)
- Testing
- Blood test, Urine sample, Hair sample
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Gastrointestinal Diseases
Correlation of Toxins With Gastrointestinal (GI) and Overall Health
The goal of this observational study is to evaluate the levels of urinary environmental toxins, heavy metals, PFAS and mycotoxins with gastrointestinal (GI) and overall health.
- Trial name
- NCT06278311
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vibrant America Clinical Lab
Disease, Cardiovascular Diseases
Biomarkers of Acrylamide, Glycidol, POPs, PFAS and Disease Outcomes and OMICs Signatures
The aim of the project is to assess the associations between biomarkers of acrylamide and glycidol exposure and disease outcomes in a case-cohort study based on two prospective cohorts with biobanks.
- Conditions
- Disease, Cardiovascular Diseases, Cancer, Environmental Exposure
- Trial name
- NCT05930626
- Testing
- Biomarkers of acrylamide, glycidol, POPs, PFAS
- Volunteers
- 9,254 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
PFAS, Environmental Exposures
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
The goal of this study is to test the efficacy and feasibility of Colesevelam administration (50% of the recommended dose) to reduce serum PFAS concentration in the Veteran population who have serum PFAS levels that exceed the…
- Conditions
- PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure
- Trial name
- PAVERS (NCT07592858)
- Testing
- Colesevelam
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Innate Inflammatory Response, Vaccination
PFAS Exposure and Immune Response to Vaccination in Adults
This clinical trial aims to investigate how exposure to Perfluorononanoic acid (PFNA), a type of per- and polyfluoroalkyl substance (PFAS), affects the immune response to the standard tetanus and diphtheria (Td) vaccine.
- Conditions
- Innate Inflammatory Response, Vaccination, Diphtheria, Tetanus
- Trial name
- NCT06588530
- Testing
- TENIVAC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Analgesia, Post Operative Pain
Clinical Utility of the Numerical Verbal Scale (NVS) and the Pain and Functional Activity Scale (PFAS) in the Management of Rescue Analgesia in Acute Postoperative Pain. Randomized Study.
Adequate postoperative pain management, along with mobilization and early oral nutrition, is the foundation for optimal recovery after surgery.
- Conditions
- Analgesia, Post Operative Pain, Acute Pain, Functional; Anesthesia
- Trial name
- EVN/EDAF (NCT07310953)
- Testing
- Group A: Rescue analgesia if NVS>4, Group B: Rescue analgesia if NVSm > 4 + FAS C
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Environmental Health Effects
Assessing PFAS Exposure for Better Health
The goal of this observational study is to determine whether a personalized PFAS (per- and polyfluoroalkyl substances) blood test and educational report-back can improve environmental health literacy (EHL), empower exposure…
- Trial name
- APEX (NCT07391397)
- Testing
- Blood Test and Report Back
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Million Marker Wellness, Inc.
Breast Cancer Screening
Adapting a Mammography Decision Aid to Support Women Living in a Community Contaminated by PFAS
This community-engaged research project will test an adapted online breast cancer screening decision aid to address the needs of women living in an area where environmental contamination has increased concern about breast cancer…
- Trial name
- NCT06098118
- Testing
- MyMammogram decision aid
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College