Clinical trials: PET / MR
Dementia
Applying PET/MR for Dementia Applications
Dementia is a common disorder affecting about 50 million people worldwide with nearly 10 million cases every year . It is characterized by cognitive impairments as well as behavior disabilities.
- Trial name
- NCT04154254
- Testing
- PET/MR
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Coronary Artery Disease, Cardiac Perfusion
Stress Adenosine Cardiac Magnetic Resonance (MR) Comparison With Single Photon Emission Computed Tomography (SPECT) Imaging
This study is designed to determine the diagnostic value of adenosine cardiac magnetic resonance (CMR) when compared with SPECT.
- Trial name
- NCT00864591
- Testing
- SPECT Imaging, Stress Adenosine CMR
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Parkinson Disease, PARK8, Parkinson Disease
Molecular Pathology and Neuronal Networks in LRRK2 Parkinson's Disease
Parkinson's Disease (PD) is a progressive neurodegenerative disease characterized clinically by bradykinesia, resting tremor, rigidity, and postural instability.
- Conditions
- Parkinson Disease, PARK8, Parkinson Disease, Idiopathic Parkinson Disease
- Trial name
- NCT03782753
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- King's College London
Breast Cancer, Chemotherapy Effect
The Prediction Model of NAC Response for Breast Cancer Based on The Parametric Dynamics Features.
The main purpose of this study is to develop a computer-aided prediction model for NAC treatment response. Based on the heterogeneity of internal parametric tumor composition commonly observed, this study will utilize the…
- Conditions
- Breast Cancer, Chemotherapy Effect, Diffusion Weighted MRI, PET Imaging
- Trial name
- NCT06370234
- Testing
- Whole body 18F-FDG Positron Emission Tomography
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Epilepsy, PET / MR
Multimodal PET Imaging With 18F-FDG/SV2A/TSPO for Resection Planning in Drug-Resistant Epilepsy
This study focuses on the application value of 18F-FDG, SV2A, and TSPO PET imaging in the preoperative localization of epileptogenic foci in epilepsy.
- Conditions
- Epilepsy, PET / MR, Synaptic Vesicle Proteins, Microglial Activation
- Trial name
- NCT07147309
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Weibing Miao, PhD
Systemic Amyloidosis, PET/MR
The Diagnostic Value of Hybrid PET/MR for Systemic Amyloidosis
Systemic amyloidosis is a multi-system disease caused by extracellular deposition of insoluble amyloid fibrils in various tissues and organs, leading to progressive organ dysfunction.
- Trial name
- NCT04006223
- Testing
- 11C-PIB or 18F-florbetapir PET/MR before biopsy and treatment, 11C-PIB or 18F-florbetapir PET/MR after treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Rectal Neoplasms
PET/MR for Staging Rectal Cancer Patients With and Without EMVI-MR
The hypothesis to be proven with this study is that the use of PET/MR on the initial staging of rectal cancers in patients with extramural vascular invasion detected by MR will detect more lesions than conventional work-up and…
- Trial name
- NCT02537340
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Prostate Cancer
18F-FCH (Fluorocholine)-PET/MR in Staging of High-Risk Prostate Cancer
This is a single centre, single arm feasibility study of 18FCH PET-MR imaging for staging patients with high risk prostate cancer.
- Trial name
- NCT01993160
- Testing
- Fluorocholine (18F-FCH) Injection, PET scan, Whole body MRI
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Invasive Breast Cancer
FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cancer
The goal of this research is to test the accuracy of PET/MRI imaging with 18F-fluorofuranylnorprogesterone (FFNP) for measuring progesterone receptor (PR) expression in patients with invasive breast cancer.
- Trial name
- NCT03212170
- Testing
- [18F]Fluorofuranylnorprogesterone (FFNP) PET/MR Imaging
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Wisconsin, Madison
Treatment
Integrated Boost to the Dominant Intraprostatic Nodule Based on Ga-68 PSMA PET/MR Study of SBRT With Prostate Cancer
The aim of this study is to test the safety and efficacy of integrated boost to the dominant intraprostatic nodule based on Ga-68 Prostate-Specific Membrane Antigen (PSMA) PET/MR in Stereotactic Body Radiation Therapy (SBRT) in…
- Trial name
- SBRT (NCT04599699)
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Changhai Hospital
Cervical Cancer, Endometrial Cancer
PET-CT vs. Integrated MR-PET Scanning of GYN Cancers
This research study is an imaging pilot study. Imaging pilot studies explore the potential benefit of one imaging approach compared to another clinically accepted approach.
- Conditions
- Cervical Cancer, Endometrial Cancer, Ovarian Cancer
- Trial name
- NCT01779128
- Testing
- PET-CT, MR-PET
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Prostate Cancer
Model of Predicting Biochemical Recurrence After Radical Prostate Cancer Based on Pre-treatment PSMA PET / MR Image Features
The purpose of this study is to investigate the predictive value of preoperative 18F-PSMA-1007 PET/MR in the predictive effect of biological recurrence (BCR) after radical prostatectomy (RP) for localized prostate cancer (PCa).
- Trial name
- NCT06604377
- Testing
- Observe
- Where
- China
- Volunteers
- 203 people
- Sponsor
- Ruijin Hospital
Multiple Sclerosis, Inflammatory Demyelinating Disease
A Study of Imaging in Demyelinating Diseases
This purpose of this study is research the usefulness of MRI with PET/CT imaging for measuring brain inflammation and its relation to Multiple Sclerosis (MS).
- Trial name
- NCT05805839
- Testing
- C-11 ER176 Radiotracer, C11 Pittsburgh Compound B, PET/CT scan
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Bladder Cancer
[68Ga] NOTA-SGC8 in the Staging of Bladder Cancer
The goal of this clinical trial is to test the imaging and diagnostic ability of [68Ga]-NOTA-SGC8 PET/MR in bladder cancer patients with different stages.
- Trial name
- NCT06005116
- Testing
- [68Ga]-NOTA-SGC8
- Where
- China
- Volunteers
- 64 people
- Sponsor
- RenJi Hospital
Brain Tumor, Brain Cancer
PET and MRI Imaging of Brain Tumors Using [18F]PARPi
This study is to collect data about how 18FPARPi can be used together with PET/positron emission tomography and MRI/magnetic resonance imaging scans to take pictures of brain cancer
- Trial name
- NCT04173104
- Testing
- PET/MR with [18F]PARPi, [18F]PARPi
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer
The Therapeutic Efficacy of 18F-FDG Combined With 18F-FAPI PET/MR in Neoadjuvant Therapy for Gastric Cancer
Gastric cancer is the fifth most common cancer worldwide and the third leading cause of cancer-related deaths. Although surgical treatment can benefit the survival of the vast majority of patients, currently only early gastric…
- Trial name
- NCT06327386
- Testing
- 18F-FAPI#18F-FDG
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Malignant Tumors, Positron-Emission Tomography
FAP PET/CT or PET/MR Production in the Diagnosis, Staging, and Efficacy Assessment of Malignant Tumors Application
This clinical trial aims to investigate the value of fibroblast activation protein PET/CT(PET/MR) in the diagnosis, staging, and evaluation of treatment outcomes in malignant tumors.
- Trial name
- NCT06270394
- Testing
- 68Ga-Fibroblast activation protein inhibitor
- Where
- China
- Volunteers
- 22 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Hepatic Malignancies
Role of FAPI PET/MR Combined With Gadoxetate Disodium in Assessing Hepatic Malignancies
This study aimed to prospectively evaluate the utility of fibroblast activation protein inhibitor (FAPI) positron emission tomography (PET)/magnetic resonance (MR) combined with gadoxetate disodium in patients with clinical…
- Trial name
- NCT06287411
- Testing
- FAPI PET/MR combined with gadoxetate disodium
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Xiao Chen
Pulmonary Hypertension
PET/MR Pre- and Post Radiotherapy for Cardiopulmonary Dysfunction Evaluation
Radiotherapy (RT) is a well-known and established therapy or adjuvant therapy for the treatment of thoracic cancer It uses a high energy radiation from x-rays, gamma rays and other charged particles that assist in damaging the…
- Trial name
- NCT04901884
- Testing
- PET/MR with 18F-FDG
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Large Vessel Vasculitis
Monitoring Large Vessel Vasculitis With PET/MR Imaging
Large vessel vasculitis (LVV) causes blood vessel inflammation leading to pain, fatigue and complications such as aneurysm formation and stroke. Treatments used can have significant side-effects.
- Trial name
- NCT03914248
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Edinburgh