Clinical trials: PET/CT
IgG4-related Disease
Characterizing IgG4-RD With 68Ga-FAPI PET/CT
68Ga-FAPI has been developed as a tumor-targeting agent as fibroblast activation protein is overexpressed in cancer-associated fibroblasts and some inflammation,such as IgG4-related disease.And it might be more sensitive than FDG…
- Trial name
- NCT04125511
- Testing
- 68Ga-FAPI
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Coronary Artery Disease
Adenosine Dual Source Computed Tomography (CT) Versus Adenosine Single Photon Emission Computed Tomography (SPECT)
Researchers hope that this new non-invasive multi-detector scanner (DSCT) will provide diagnostic information comparable to the combination of traditional SPECT (for function and blood flow) and CT imaging (for a precise…
- Trial name
- NCT00892307
- Testing
- Dual Source Multidetector CT (DSCT) w/ Adenosine enhancement
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Cedars-Sinai Medical Center
Breast Cancer
Pilot Trial to Assess 68Ga Bombesin PET/CT (NeoB) Imaging for Staging of Breast Cancer
This phase IIb pilot study will enrol 20 patients (women) presenting with metastatic breast cancer (ER/PR + HER2- on histology) who require imaging for staging or re-staging of their disease.
- Trial name
- NCT05889728
- Testing
- [68Ga]GA-NeoB
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- St Vincent's Hospital, Sydney
Primary Aldosteronism
68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Primary Aldosteronism: The GAPA Randomized Clinical Trial
To compare the 68Ga-Pentixafor PET/CT and adrenal vein sampling on the long-term outcomes of primary aldosteronism (PA) patients with adrenal nodule (≥1cm)
- Trial name
- GAPA (NCT06238232)
- Testing
- 68Ga-Pentixafor PET/CT
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Chongqing Medical University
Colorectal Cancer Recurrent
Ga-68-FAPI-46 PET for CRC Recurrence Detection in Elevated CEA
This single-center, phase II clinical trial investigates the diagnostic efficacy of Ga-68-FAPI-46 PET scans in detecting colorectal cancer (CRC) recurrence during post-treatment surveillance, particularly in patients with…
- Trial name
- Ga-68-FAPI-46 (NCT06769828)
- Testing
- Ga-68-FAPI-46
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Koo Foundation Sun Yat-Sen Cancer Center
Nasopharyngeal Carcinoma
A Phase III Trial in NPC With Post-radiation Detectable Plasma EBV DNA
Nasopharyngeal carcinoma (NPC) is a geographically endemic, Epstein-Barr virus (EBV)-associated carcinoma of epidermoid origin. It occurs most commonly in Southern China and Southeast Asia.
- Trial name
- NCT02363400
- Testing
- MEP
- Where
- 6 sites in Taiwan
- Volunteers
- 10 people
- Sponsor
- National Health Research Institutes, Taiwan
Cervical Cancer Stage, Imaging Modalities
The Validity of the Use of Imaging in Cervical Cancer Staging
The study wil aim to investigate the accuracy of imaging in the staging of women diagnosed with cervical cancer
- Trial name
- NCT06487767
- Testing
- Surgery
- Where
- South Africa
- Volunteers
- 100 people
- Sponsor
- University of Pretoria
Non-small Cell Lung Carcinoma
Use of [18]F-FDG on PET/CT as an Alternative Non-invasive Method for Staging of Lung Cancer
To evaluate the diagnostic accuracy of the 18Fluor-fluorodeoxyglucose ([18F]FDG) in the Positron Emission Tomography/Computed Tomography (PET/CT) as compared to mediastinoscopy for staging of non-small cel lung carcinoma.
- Trial name
- NCT02664792
- Testing
- Use of [18f]FDG - PET/CT for the diagnosis and staging of non-small cell lung carcinoma
- Where
- Brazil
- Volunteers
- 108 people
- Sponsor
- Latin American Cooperative Oncology Group
Malignant Tumor, Positron Emission Tomography
68Ga-TCR-FAPI PET/CT in Patients With Various Types of Cancer
Adding targeted covalent radiopharmaceutical (TCR) moiety to fibroblast activation protein inhibitor (FAPI) can increase tumor uptake and tumor retention in pre-clinical studies.
- Conditions
- Malignant Tumor, Positron Emission Tomography, Fibroblast Activation Protein Inhibitor
- Trial name
- NCT06084767
- Testing
- 68Ga-TCR-FAPI PET/CT
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Sarcoma
PET Scan Combined With CT Scan in Evaluating Treatment Response in Patients Undergoing Treatment for Bone Cancer or Soft Tissue Sarcoma
RATIONALE: Diagnostic procedures, such as PET scan and CT scan, may help doctors determine the extent of cancer and predict a patient's response to treatment and help plan the best treatment.
- Trial name
- NCT00335751
- Testing
- positron emission tomography computed tomography (PET/CT)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Bladder Cancer, Urothelial Carcinoma
18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy
This research study is studying a positron emission tomography (PET) agent called 18F-fluciclovine to evaluate how well 18F-fluciclovine-PET scans determine the extent of muscle invasive bladder cancer (as compared to regular CT…
- Trial name
- NCT04018053
- Testing
- 18F-fluciclovine, PET/CT
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Brigham and Women's Hospital
Lung Cancer (Diagnosis)
18F-FAPI PET in Lung Cancer
This study aims to evaluate the diagnostic efficacy and prognostic value of 18F-FAPI PET/CT in lung cancer.
- Trial name
- NCT07370805
- Testing
- 18F-FAPI PET
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Hibernation, Myocardial, Complete Occlusion of Coronary Artery
The Success of Opening Single CTO Lesions to Improve Myocardial Viability Study (SOS-comedy)
The purpose of this study is to investigate the effect of percutaneous coronary intervention (PCI) on myocardial viability in coronary artery disease patients with single coronary total occlusion (CTO) lesions.
- Trial name
- NCT02767401
- Testing
- stenting or balloon expansion, aspirin, clopidogrel, ticagrelor, atorvastatin, rosuvastatin, betaloc
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Crohn Disease
A Non-invasive Diagnostic Model for Intestinal Fibrosis in Crohn's Disease Based on 18F-FAPI PET Imaging
Crohn's disease (CD) is a chronic transmural inflammatory bowel disease. Prolonged episodes of inflammation can lead to intestinal fibrosis, leading to intestinal stenosis and obstruction.
- Trial name
- NCT05824962
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xiao Chen
Primary Malignant Liver Neoplasm
Yttrium-90 (Y90) Glass Microspheres PET/CT in Imaging Patients With Liver Tumors
This clinical trial studies how well yttrium-90 (Y90) glass microspheres positron emission tomography (PET)/computed tomography (CT) works in imaging patients with liver tumors .
- Trial name
- NCT03109262
- Testing
- Computed Tomography (CT), Positron Emission Tomography (PET), 90-Yttrium (Y-90) Glass Microspheres
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Stanford University
Colorectal Cancer
PET and CT Scans in Patients With Locally Advanced Primary Rectal Cancer That Can Be Removed During Surgery
RATIONALE: Diagnostic procedures, such as PET and CT scans, may improve the ability to detect the extent of locally advanced primary rectal cancer and may also help to measure a patient's response to treatment.
- Trial name
- NCT00004891
- Testing
- chemotherapy, computed tomography, conventional surgery
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Clear Cell Renal Cell Carcinoma
68Ga-NY104 PET/CT for the Detection of Clear Cell Renal Cell Carcinoma in Presurgical Patients With Renal Masses
This is a prospective, single-center, single-arm, diagnostic phase 2 study in patients who have renal masses scheduled for surgical resection.
- Trial name
- NCT05879510
- Testing
- 68Ga-NY104 PET/CT
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Peking Union Medical College Hospital
Patients Undergoing PET/CT Investigation or Nuclear Medicine Therapy
New AI-based Technologies in Nuclear Medicine
The study aims to identify and predict radiopharmaceutical extravasation events using new semi-quantitative parameters and machine learning models. It involves dose rate measurements to develop metrics for real-time monitoring.
- Trial name
- AI-basedMedNuc (NCT07174089)
- Testing
- RadEye SPRD-ER device: spectrometric radiation detector capable of detecting gamma radiation.
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Healthy (Controls), Healthy Volunteers
Ultralow Dose PET Imaging of SSTR2 Radiotracer Uptake
The goal of this clinical trial is to evaluate an investigational ultralow dose positron emission tomography (PET) imaging technique for neuroendocrine tumor detection and monitoring.
- Conditions
- Healthy (Controls), Healthy Volunteers, Neuroendocrine (NE) Tumors
- Trial name
- NCT07284589
- Testing
- 68Ga-Dotatate
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Akiva Mintz
Glioma
18F-FET PET/CT in the Management of Glioma
O-(2-[18F]-fluoroethyl)-L-tyrosine (FET) is a tracer for positron emission tomography (PET). The Response Assessment in Neuro-Oncology (RANO) working group has officially recommended 18F-FET PET in the management of patients with…
- Trial name
- NCT06563024
- Testing
- 18F-FET PET/CT
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Buddhist Tzu Chi General Hospital