Clinical trials: PCOS (Polycystic Ovary Syndrome)
Polycystic Ovary Syndrome
Letrozole or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome.
The purpose of this study is to compare and determine the efficacy of letrozole administration to that of laparoscopic ovarian diathermy (LOD) in infertile women with Polycystic ovary syndrome(PCOS)not responding to treatment…
- Trial name
- NCT00956267
- Testing
- Letrozole, Laparoscopic ovarian diathermy (LOD)
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Mansoura University
Treatment Resistant Disorders
Adding L-carnitine in Clomiphene Resistant Polycystic Ovary Improves the Quality of Ovulation and the Pregnancy Outcome
Adding L-carnitine is more successful than clomiphene as a first line therapy for ovulation induction in women with clomiphene resistant PCOS
- Trial name
- NCT01665547
- Testing
- l-carnitine
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Polycystic Ovary Syndrome, Diabetes, Gestational
Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome
Randomized, placebo controlled clinical trial that evaluate the role of taking metformin therapy during pregnancy in women with polycystic ovarian syndrome(PCOS) in reducing the development of gestational diabetes(GDM) and…
- Trial name
- MGDPCOS (NCT02802215)
- Testing
- metformin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
A Reduced Carbohydrate Diet Intervention for Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) affects 5-10% of women of reproductive age, and is associated with infertility, risk for obesity and type 2 diabetes, and impaired quality of life.
- Trial name
- NCT01028989
- Testing
- Reduced Glycemic Load Diet, Standard Diet
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Polycystic Ovary Syndrome
Effect of Laser Puncture Versus Ultraviolet Radiation on Women With Polycystic Ovarian Syndrome
Obese women with polycystic ovarian syndrome aged between 25 and 35 years old will be divided into three groups. For three months, group (A) will receive laser puncture (3 sessions per week), along with a metformin…
- Trial name
- NCT05986838
- Testing
- aser puncture, ultraviolet radiatio, Metformin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Myoinositol, L-arginine and Chromium With Letrozole for Ovulation Induction in Polycystic Ovarian Syndrome Patients
The aim of the study is to compare and assess the efficacy of combined letrozole with myoinositol, chromium, or L-arginine in infertile women with PCOS.
- Trial name
- NCT06405243
- Testing
- Myoinositol, Chromium, l-arginine
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
PCOS, Vitamin D Deficiency
Vitamin D for Polycystic Ovary Syndrome Clomiphene Resistant Women
This study is determining the therapeutic effect of Vitamin D supplements to Pcos clomiphene resistant polycystic ovarian syndrome Women. Half of patients will receive Vitamin D with metformin while other half metformin only.
- Trial name
- NCT04010942
- Testing
- Vit D, Metformin, Clomiphene
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
Effects of GLP-1 Analogue Combined With Metformin and Metformin on Gonadal and Metabolic Profiles in Chinese Overweight/Obese PCOS Patients With Hyperandrogenemia.
To study the effects of GLP-1 analogues combined with metformin and metformin on gonadal and metabolic profiles in PCOS patients with BMI ≥ 24 in China. 60 cases of overweight PCOS patients were collected from Shengjing hospital.
- Trial name
- NCT04969627
- Testing
- Metformin, Exenatide
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Bing He
Polycystic Ovary Syndrome
The Study of Polycystic Ovary Syndrome (PCOS) and Questionnaire
Polycystic ovary syndrome (PCOS) is an extremely common disorder in women of reproductive age. Diagnosis of PCOS is principally based on clinical and physical findings.
- Trial name
- NCT01256970
- Where
- Taiwan
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Adverse Effect of Oral Contraceptives, Sequela
Contraceptive Pill and Hormonal Vaginal Ring in Women With Polycystic Ovary Syndrome
The main aims of this study are: to investigate and compare the effects of long lasting use (59 weeks) of vaginal and oral contraceptives on androgen secretion, insulin and glucose metabolism, lipid profile, and serum levels of…
- Trial name
- NCT01588873
- Testing
- oc:E-E-desogestrel/vaginal ring:E-E -ethonogestrel
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Polycystic Ovary Syndrome
Reproductive Endocrinology Oxford Study (RepOx)
This is a prospective observational study that aims to identify the underlying mechanisms of PolyCystic Ovarian Syndrome (PCOS) and associated comorbidities such as subfertility, miscarriage; and pregnancy complications such as…
- Trial name
- RepOx (NCT05177562)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 1,175 people
- Sponsor
- University of Oxford
Polycystic Ovary Syndrome, Obesity
Omega 3 Polyunsaturated Fatty Acids (PUFA) or Magnesium in Obese Polycystic Ovary Syndrome Patients
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in reproductive age women. PCOS is usually characterized by an excessive androgen production, menstrual irregularities, and polycystic ovaries.
- Trial name
- OMgObPCOS (NCT02521753)
- Testing
- Metformin, Magnesium, PUFA
- Where
- Mexico
- Volunteers
- 123 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Polycystic Ovary Syndrome
Adipose Tissue Gene Expression Profiles in Women With Polycystic Ovary Syndrome (PCOS) Versus Controls
Adipose tissue is a central organ in mediating metabolic health. There is some evidence that women with polycystic ovary syndrome (PCOS) have a degree of adipose tissue dysfunction which may negatively affect their metabolic…
- Trial name
- NCT01195142
- Where
- 2 sites in Ireland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Adelaide and Meath Hospital
PCOS
An Integrated Self-Management Intervention for Adolescents With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder, affecting 7%-18% of reproductive-age women. Women with PCOS are at increased risk for a number of adverse physical and mental health outcomes.
- Trial name
- NCT03600337
- Testing
- Working to Optimize Wellness in Tees with PCOS (WOW)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Texas at Austin
Polycystic Ovary Syndrome
The Clinical Trial of Acupuncture Pre-treatment on PCOS
This is a study protocol for a multicenter, randomized, and controlled trial. In this protocol, we present a randomized controlled trial comparing acupuncture pretreatment followed by letrozole vs letrozole alone in polycystic…
- Trial name
- PCOSAPct (NCT02491320)
- Testing
- Pre-treatment acupuncture, Letrozole
- Where
- China
- Volunteers
- 384 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Polycystic Ovary Syndrome
Vitamin D for the Treatment of Women With Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine if vitamin D will improve insulin resistance, inflammation, and overall well-being in women with PCOS.
- Trial name
- NCT00907153
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Milton S. Hershey Medical Center
Polycystic Ovarian Syndrome
The Efficacy and Safety Study of Tung's Acupuncture for Polycystic Ovarian Syndrome
This study evaluates the efficacy and safety in improving ovarian function of polycystic ovarian syndrome in adults. Half of patients will receive Tung's acupuncture therapy, while the other half will receive Diane-35(CPA/EE) as…
- Trial name
- NCT02729545
- Testing
- Tung's acupuncture, Cyproterone acetate/ethinylestradiol (CPA/EE)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Hospital of Integrated Traditional Chinese and Western Medicine
Polycystic Ovary Syndrome, Body Weight
Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss
Weight reduction is the most important treatment target in obese women with polycystic ovary syndrome (PCOS), yet it is usually hardly achievable with lifestyle intervention alone.
- Trial name
- NCT02941445
- Testing
- sitagliptin and metformin, Metformin
- Volunteers
- 24 people
- Sponsor
- University Medical Centre Ljubljana
Polycystic Ovary Syndrome
High Intensity Interval Training or Strength Training in Women With Polycystic Ovary Syndrome
The aim is to investigate whether strength training or high intensity interval training is effective in improving insulin sensitivity, cardiovascular outcomes, body composition and reproductive outcomes in women with Polycystic…
- Trial name
- NCT01919281
- Testing
- strength training, interval training
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Norwegian University of Science and Technology
Polycystic Ovary Syndrome, Dietary Habits
Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome
The purpose of the study is to identify lifestyle factors associated with PCOS and understand how diet and activity levels impact features of PCOS.
- Conditions
- Polycystic Ovary Syndrome, Dietary Habits, Physical Activity
- Trial name
- NCT01859663
- Where
- 3 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Cornell University
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