Clinical trials: PCOS
Polycystic Ovary Syndrome (PCOS) Women
Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS
This double-blind, placebo-controlled, parallel-group randomized controlled trial evaluated changes in metabolic, vitamin B12, iron-status, erythropoietic, and hematological parameters among women with polycystic ovary syndrome…
- Trial name
- MET-PCOS (NCT07793838)
- Testing
- Metformin
- Where
- Jordan
- Volunteers
- 400 people
- Sponsor
- Jerash Private University
Polycystic Ovary Syndrome (PCOS), Menstrual Symptoms
Mindfulness-Based Education For Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS), also known as polyendocrine metabolic ovarian syndrome (PMOS), is the most common endocrinologic disorder to affect women. Despite this, the disease's pathophysiology remains unclear.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Menstrual Symptoms, Stress, Quality of Life
- Trial name
- NCT07718217
- Testing
- Mindfulness-Based Polycystic Ovary Syndrome (PCOS) Education
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
PCOS
PCOS and Brain Health
The purpose of this study is to determine how polycystic ovary syndrome (PCOS) impacts overall brain health, such as cerebral blood flow (CBF), brain structure and connectivity, and cognitive performance.
- Trial name
- NCT07727512
- Testing
- MRI Visit, Laboratory Visit
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
PCOS (Polycystic Ovary Syndrome), Obese Adolescents
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)
This pilot randomized controlled study will plan to enroll 36 adolescent females with Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) to evaluate the effectiveness and feasibility of a tailored…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Obese Adolescents, Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight Adolescents
- Trial name
- Beef+ (NCT07780188)
- Testing
- Beef+
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Texas A&M University
Polycystic Ovary Syndrome (PCOS)
Intra-Ovarian PRP Compared With Gonadotropin for Ovarian Response in Letrozole-Resistant PCOS
The goal of this randomized clinical trial is to compare autologous platelet-rich plasma (PRP) with gonadotropin for improving ovarian response in women with letrozole-resistant polycystic ovary syndrome (PCOS).
- Trial name
- NCT07777640
- Testing
- Autologous Platelet-Rich Plasma (PRP), Gonadotropin
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- Bangladesh Medical University
Polycystic Ovarian Syndrome (PCOS), Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Comparison of Clomiphene Alone Versus Clomiphene Plus Sildenafil for Ovulation in Women With Polycystic Ovary Syndrome
The goal of this randomized clinical trial is to compare the effectiveness of clomiphene citrate alone with clomiphene citrate combined with sildenafil citrate for inducing ovulation and achieving pregnancy in women with…
- Trial name
- NCT07769476
- Testing
- Clomiphene Citrate 100 mg, Sildenafil Citrate 25Mg Tab
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Nishtar Medical University
Insulin Resistant PCOS
Magnesium Oxide and Letrozole Versus Letrozole Alone on Ovarian Response in Insulin Resistant PCOS
Does pretreatment with magnesium oxide followed by letrozole increase ovulation rate? What medical problems do participants have when taking drug magnesium oxide and letrozole? Researchers will compare magnesium oxide and…
- Trial name
- NCT07766590
- Testing
- Experimental drug: Magnesium oxide (365 mg), Letrozole 2.5mg
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Polycystic Ovarian Syndrome (PCOS)
This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms.
The rationale for this study is to observe the impact of a consumer-grade commercially available product called Milamend Hormone Balance on quality of life and hormonal health in women with self-reported symptoms associated with…
- Trial name
- NCT07764328
- Testing
- A dietary supplement powder for women
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Mila Mend Inc.
PCOS
Letrozole High Dose (10 mg) Compared to Letrozole Low Dose( 5 mg) for Ovarian Stimulation in Infertile Women With Polycystic Ovary Syndrome
The goal of this clinical trial is to learn if drug letrozole 10mg for 5 days works better than letrozole 5mg for 5 days for ovarian stimulation in infertile women with PCOS.
- Trial name
- PCOS OID (NCT07759518)
- Testing
- Tab.Letrozole 10 mg for 5 days, Tab.Letrozole 5mg for 5 days
- Where
- Bangladesh
- Volunteers
- 86 people
- Sponsor
- Mst.Sumyara Khatun
Polycystic Ovary Syndrome (PCOS) Women, Insulin Resistance Syndrome
Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in Jordan
This prospective longitudinal interventional study aims to evaluate the effects of routine metformin therapy on metabolic, iron-related, erythropoietin, lipid, and hematological parameters in adult women with polycystic ovary…
- Trial name
- Metformin-APO (NCT07759674)
- Testing
- Metformin
- Where
- Jordan
- Volunteers
- 25 people
- Sponsor
- Jerash Private University
Polyendocrine Metabolic Ovarian Syndrome, Stress
The Effect of Standardized Withania Somnifera Extract on Endocrine, Metabolic, and Psychometric Parameters, in Women With Polyendocrine Metabolic Ovarian Syndrome
The objective of this study is to ascertain the impact of a standardized Withania somnifera extract on endocrine, metabolic, and psychometric parameters in women diagnosed with polyendocrine metabolic ovarian syndrome.
- Conditions
- Polyendocrine Metabolic Ovarian Syndrome, Stress, Polycystic Ovarian Syndrome (PCOS), Depression Symptoms
- Trial name
- NCT07750899
- Testing
- Withania somnifera, Active comparator
- Where
- Poland
- Volunteers
- 28 people
- Sponsor
- Medical University of Lodz
Polycystic Ovary Syndrome (PCOS), Female Infertility
Comparison of IVF Outcomes Between PPOS and Antagonist Protocols in Women With PCOS
This study aims to compare the outcomes of two ovarian stimulation protocols used in in vitro fertilization (IVF): the progestin-primed ovarian stimulation (PPOS) protocol and the GnRH antagonist protocol.
- Trial name
- PPOS-PCOS-IVF (NCT07394530)
- Testing
- Progestin-Primed Ovarian Stimulation (PPOS), GnRH Antagonist Protocol
- Where
- Vietnam
- Volunteers
- 400 people
- Sponsor
- Hanoi General Hospital (Vietnam)
PCOS (Polycystic Ovary Syndrome)
Clinical Research Cohort for Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a multifactorial metabolic-endocrine disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology.
- Trial name
- PCOS (NCT07739940)
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Guangdong Women and Children Hospital
PCOS (Polycystic Ovary Syndrome)
Development and Clinical Application of ApoC3 Protein as a Predictive Biomarker for Insulin Resistance in Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is the most common reproductive endocrine disorder causing infertility and miscarriage in women.
- Trial name
- NCT07739953
- Testing
- observational study
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Polycystic Ovary Syndrome (PCOS), Thrombophilia
Construction of a Multi-dimensional Risk Assessment System: a Clinical Study of Polycystic Ovary Syndrome Complicated With Thrombophilia
This observational case-control study aims to develop a multidimensional risk assessment model for thrombophilia-related abnormalities in females with polycystic ovary syndrome (PCOS).
- Trial name
- NCT07571096
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangdong Women and Children Hospital
Polycystic Ovary Syndrome (PCOS), Metabolic Dysfunction-Associated Steatotic Liver Disease
Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS)
This single-center, prospective, observational, cross-sectional mechanistic pilot study will evaluate whether polycystic ovary syndrome (PCOS) contributes to hepatic steatosis in adolescent girls independently of adiposity.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Metabolic Dysfunction-Associated Steatotic Liver Disease, Pediatric Obesity, Hyperandrogenism
- Trial name
- COMPASSpedPCOS (NCT07731373)
- Testing
- Extended Serum Biomarker and Hormonal Panel, Liver Elastography with Controlled Attenuation Parameter, Targeted Genotyping of PNPLA3 rs738409 and HSD17B13 rs72613567
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Polycystic Ovary Syndrome (PCOS), Insulin Resistance
Evaluation of Serum Preptin Levels in Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age and is strongly associated with insulin resistance and metabolic dysfunction.
- Trial name
- PREPTIN-PCOS (NCT07736079)
- Volunteers
- 60 people
- Sponsor
- GÜLDEN ANATACA
PCOS GnRH Antagonist and GnRH Agonist IVF/ICSI Cycles, IVF Outcomes
Effect of Estradiol Pretreatment on Follicular Synchronization and IVF Outcomes in Women With Polycystic Ovary Syndrome Undergoing ICSI Using GnRH Antagonist Protocol
This randomized clinical trial included 60 infertile women diagnosed with PCOS undergoing ICSI cycles using a GnRH antagonist protocol.
- Trial name
- NCT07727863
- Testing
- GnRH Antagonist Protocol, Estradiol Valerate 4mg
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
PCOS (Polycystic Ovary Syndrome)
Effects of Folic Acid and Vitamin E on Hormones in Polycystic Ovary Syndrome
The goal of this prospective comparative interventional study is to evaluate serum Ezrin levels and investigate the effects of one-month supplementation with vitamin E and folic acid in Iraqi women of reproductive age diagnosed…
- Trial name
- NCT07723443
- Testing
- Vitamin E 400, Folic Acid 5 Mg Oral Tablet
- Where
- Iraq
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Polycystic Ovarian Syndrome (PCOS), Reproductive Health
Management of Polycystic Ovarian Syndrome-associated Reproductive Dysfunction Through Kefir Supplementation
Polycystic ovary syndrome (PCOS) affect around 6-12% of women of age 18-25 years. Kefir contains bioactive compounds such as lactic acid bacteria, yeast, peptides, polysaccharides and organic acids and acts as a good probiotic…
- Trial name
- NCT07711782
- Testing
- (C0) Control group, (G1) Experimental group
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Lahore