Clinical trials: PCOS
Polycystic Ovary Syndrome, Diabetes, Gestational
Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome
Randomized, placebo controlled clinical trial that evaluate the role of taking metformin therapy during pregnancy in women with polycystic ovarian syndrome(PCOS) in reducing the development of gestational diabetes(GDM) and…
- Trial name
- MGDPCOS (NCT02802215)
- Testing
- metformin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Stroke, Spinal Cord Diseases
Use of tDCS Stimulation in Neurological and Gynaecological Conditions
The aim of the study is to test the effect of tDCS stimulation on upper and lower limb function in neurological patients and to reduce pain in gynaecological patients.
- Conditions
- Stroke, Spinal Cord Diseases, Nerve Root Disorder, Endometriosis
- Trial name
- tDCS (NCT06891690)
- Testing
- tDSC stimulation
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Polycystic Ovary Syndrome Health-related Quality of Life
Translation and Validation of the French mPCOSQ (mPCOSQ-F).
This study is a prospective, observational, bicentric study, evaluating the validity and reliability of a French version of the mPCOSQ questionnaire (mPCOSQ-F), used to assess health-related quality of life (HRQOL) in women with…
- Trial name
- NCT07016035
- Testing
- mPCOSQ-F and SF-36
- Where
- France
- Volunteers
- 350 people
- Sponsor
- CHU de Reims
Insulin Resistance, Oxidative Stress
Alpha Lipoic Acid and Polycystic Ovary Syndrome
The study will recruit 40 subjects with Polycystic Ovary Syndrome (PCOS) as defined by the NIH criteria. The subjects will be pre-screened for insulin sensitivity using fasting insulin and glucose levels and oral glucose…
- Trial name
- NCT00505427
- Testing
- Alpha Lipoic Acid
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, San Francisco
Anovulation, Irregular Menses
Uterine and Endometrial Volume in PCOS and HPOD
Group II causes of anovulation according to the World Health Organization include polycystic ovary syndrome (PCOS) and the less common dysfunction of the hypothalamic-pituitary-ovarian axis (HPOD).
- Trial name
- NCT06211608
- Testing
- Two-dimensional and three-dimensional ultrasound of the female reproductive organ
- Where
- Poland
- Volunteers
- 648 people
- Sponsor
- Jagiellonian University
Hypogonadotropic Hypogonadism, Kallmann Syndrome
Kisspeptin Administration in the Adult
The goal of this study is to learn about the role of kisspeptin in the reproductive system. Kisspeptin is a naturally occurring hormone in humans that causes the release of other hormones, including gonadotropin-releasing hormone…
- Conditions
- Hypogonadotropic Hypogonadism, Kallmann Syndrome, GnRH Deficiency, PCOS
- Trial name
- NCT00914823
- Testing
- kisspeptin 112-121, GnRH
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
PCOS, Obesity
Liraglutide as Add on Therapy on Metformin in Women With Polycystic Ovary Syndrome
The purpose of this study was to determine whether combined treatment with liraglutide and metformin is more effective than metformin as monotherapy in the treatment of obese women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT02483299
- Testing
- Metformin, Glucophage tablets and Victoza
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- University Medical Centre Ljubljana
Polycystic Ovary Syndrome
Characterization of a Prospective Cohort of Women With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women. PCOS is characterized by increase levels of testosterone, unwanted hair growth, adiposity, irregular menstrual cycle, and infertility.
- Trial name
- NCT02010814
- Where
- Denmark
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
PCOS(Insulin Resistant)
Effect of Pioglitazone vs Metformin on Clinical, Biochemical and Hormonal Parameters of Insulin Resistant PCOS
Women with PCOS with HOMA-IR >2 fulfilling inclusion and exclusion criteria are randomly allocated into two groups: group A: pioglitazone 30 mg once daily and group B: Metformin 500 thrice daily for 3 months.Each group contains…
- Trial name
- PCOS HOMA IR (NCT07472179)
- Testing
- Pioglitazone 30 Mg Oral Tablet, metformin 500 mg thrice daily
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Mst.Sumyara Khatun
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Polycystic Ovary Syndrome (PCOS) and Sleep Apnea
Polycystic ovary syndrome (PCOS) affects 5-10% of women in the United States. Its onset is usually at the time of puberty with manifestations of menstrual irregularity, hirsutism, and obesity.
- Trial name
- NCT00203996
- Testing
- continuous positive airway pressure (CPAP), depot leuprolide plus estrogen/progestin replacement, pioglitazone
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Chicago
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
PCOS and US Cavitation
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Women with this syndrome may have infrequent menstrual periods or amenorrhea and excess androgen levels.
- Trial name
- NCT05880550
- Testing
- ultrasound cavitation in addition to aerobic ex, aerobic exercises.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Effects of Alpha-acid Lipoic in PCOS Women
The aim of our study is to investigate the effects of six months treatment with alpha-lipoic acid on clinical, endocrine and metabolic features in women affected by PCOS.
- Trial name
- NCT02666170
- Testing
- Alpha-lipoic acid
- Volunteers
- 40 people
- Sponsor
- Catholic University of the Sacred Heart
Polycystic Ovarian Syndrome (PCOS), Patients Sensitive to Exogenous Gonadotropins
In Vitro Maturation (IVM) of Human Oocytes
We hypothesize that the combination of natural cycle IVF or low dose gonadotropin injection combined with In Vitro Maturation (IVM) (Natural IVF/IVM) is a viable option for a selected population of infertility patients who cannot…
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Patients Sensitive to Exogenous Gonadotropins, Ovarian Hyper Stimulation Syndrome (OHSS)
- Trial name
- IVM (NCT01843569)
- Testing
- In Vitro maturation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Polycystic Ovary Syndrome
Intrauterine Environment in Polycystic Ovary Syndrome (PCOS) Probands
Polycystic ovary syndrome (PCOS) is among the most common endocrine disorders in premenopausal women, affecting 7-10% of this population.
- Trial name
- NCT00364949
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Polycystic Ovary Syndrome, Anovulation
The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women
The purpose of our study was to conduct a placebo controlled, double-blind randomized trial in chronic oligoovulatory or anovulatory , hyperandrogenic, infertility patients comparing the effects of adjuvant metformin plus…
- Conditions
- Polycystic Ovary Syndrome, Anovulation, Oligoovulation, Infertility
- Trial name
- NCT00413179
- Testing
- Metformin, Clomiphene citrate
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Polycystic Ovary Syndrome
the Effect of Diane-35 Pretreatment on In-vitro Fertilization Outcome for Patients With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome is the most common endocrine disorder in women, is estimated to affect more than 5% of the population and is associated with chronically elevated serum androgen concentrations.Evidence suggests that…
- Trial name
- NCT01752270
- Testing
- Diane-35 pretreatment
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Polycystic Ovary Syndrome
Evaluation of Endocrine and Metabolic Parameters in the New Diagnostic Phenotypes of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a very frequent endocrine disease of women in reproductive age, with an estimated prevalence of 5 to 10 % according to the studied population.
- Trial name
- NCT00784615
- Testing
- Blood samples, transvaginal ultrasound
- Where
- Argentina
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Córdoba
Polycystic Ovary Syndrome
Letrozole Dose Increments in PCOS Patients Resistant to Letrozole
Objectives: To study the effect of Letrozole dose increments on ovulation rate and endometrial thickness as a primary outcomes in patients with polycystic ovary syndrome who previously resistant to letrazole conventional dose…
- Trial name
- NCT06403488
- Testing
- Letrozole 2.5mg
- Where
- 2 sites in Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Infertility
Evaluation of Anti-mullerian Hormone(AMH) Levels as a Predictive Factor of Response to Weight Loss Treatment in Obese Infertile Women With Poly Cystic Ovary(PCOS)
This study is a prospective before \& after clinical trial to compare the basal and 3 months after diet anti-mullerian hormone levels between responders and non-responders to weight loss diet in obese infertile women with PCOS…
- Trial name
- NCT01792362
- Testing
- Weight loss diet
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Polycystic Ovary Syndrome, Overweight and Obesity
Weight Loss Intervention in Women With PCOS
The proposed single arm 6 mo. trial will assess the impact of weight loss and fat loss due to a multicomponent remotely-delivered lifestyle intervention on ovulation rates and time-to-ovulation in overweight and obese women with…
- Trial name
- NCT03677362
- Testing
- Weight loss intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Kansas Medical Center