Clinical trials: PAR
Perennial Allergic Rhinitis (PAR)
Study of CM512 Injection in Patients With Perennial Allergic Rhinitis on Background Therapy
This is a randomized, double-blind, placebo-parallel controlled phase II study to evaluate the safety and efficacy of CM512 in patients with perennial allergic rhinitis on background therapy
- Trial name
- NCT07890350
- Testing
- CM512
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Keymed Biosciences Co., Ltd.
Rhinitis, Allergic, Perennial
To Assess the Safety and Efficacy of Ciclesonide Applied as a Nasal Spray in the Treatment of Perennial Allergic Rhinitis (BY9010/M1-402)
The primary objective of this study is to demonstrate the efficacy of ciclesonide applied as a nasal spray once daily in patients with PAR. The secondary objectives are to evaluate Quality-of-Life and safety.
- Trial name
- NCT00659750
- Testing
- Ciclesonide
- Where
- 23 sites in United States
- Volunteers
- 418 people
- Sponsor
- AstraZeneca
Parkinson Disease
EEG and Pharmacological Exploration of Executive Dysfunctions Induced by STN-DBS in PD
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) remarkably improves motor functions in patients with Parkinson disease (PD).
- Trial name
- EEGDBSNAd (NCT01796483)
- Testing
- Clonidine (Catapressan)
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Myopia, Dry Eye Disease (DED)
Study of Eye Fatigue From Digital Screens and Its Impact on Visual Performance in People With Normal Vision and Myopia, With and Without Dry Eye Symptoms and Signs
The goal of this observational study is to investigate the effects of eye fatigue induced by screen task on dry eye disease (DED) signs and symptoms, visual performance, and visual behavior in young adults with and without DED…
- Trial name
- RReye (NCT07844408)
- Testing
- Eye Exams, Ocular Biometry and Aberrometry, Wearing a Smartwatch
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Essilor International
Rhinitis, Allergic, Perennial
A Phase-IV, Open-label Study to Evaluate Safety/Tolerability of Once-daily AVAMYS (TM) Aqueous Nasal Spray 110mcg Among Vietnamese Adult Patients With Established Perennial Allergic Rhinitis
Allergic rhinitis is an IgE-mediated, inflammatory disorder of the upper airway that occurs following allergen exposure. Perennial Allergic Rhinitis (PAR) starts in early childhood and occurs all year around.
- Trial name
- AVY-REG00108VN (NCT01270958)
- Testing
- Avamys aqueous nasal spray 110mcg
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- GlaxoSmithKline
Onychomycosis of Toenail
URGO MICKAEL Filmogel, Topical Treatment of Onychomycosis
The objective of this clinical study is to evaluate the performance of URGO MICKAEL Filmogel as a topical treatment for mild to moderate onychomycosis
- Trial name
- MICKAEL (NCT07828184)
- Testing
- URGO MICKAEL Filmogel
- Where
- France
- Volunteers
- 54 people
- Sponsor
- CEN Biotech
Carcinoma, Hepatocellular
A Study of Electromagnetic Waves in the Treatment of the Advanced Hepatocarcinoma
Hepatocarcinoma (HCC) is the first cause of deaths due to cancer worldwide. More than one million two hundred thousand new patients are diagnosed each year.
- Trial name
- THBC002 (NCT00440934)
- Testing
- Amplitude-modulated electromagnetic fields
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pasche, Boris, M.D.
N-13 Ammonia Safety
Safety of PET MPI Using the CRCHUM N-13 Ammonia
Positron emission tomography (PET) myocardial perfusion imaging (MPI) is an examination that helps to assess the function and perfusion of the heart.
- Trial name
- NCT03275584
- Testing
- N-13 ammonia intravenous injection
- Where
- Canada
- Volunteers
- 20,000 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Perennial Allergic Rhinitis
Evaluation of a Novel Questionnaire to Assess Patient Satisfaction With and Preference of Intranasal Corticosteroids for the Treatment of Allergic Rhinitis
This is an open-label, randomized, multicenter, 2-way crossover study in subjects 12 years or older with perennial allergic rhinitis (PAR) to evaluate the psychometric properties of a novel-patient administered assessment of…
- Trial name
- NCT01287364
- Testing
- ciclesonide hydrofluoroalkane (HFA) nasal aerosol, mometasone nasal inhalation
- Where
- 6 sites in United States
- Volunteers
- 185 people
- Sponsor
- Sumitomo Pharma America, Inc.
Fatigue Symptom, Lymphoma Non-Hodgkin
Study of the Association Between Fatigue Experienced by Patients and the Specific Side Effects of CART Cells, During the First Month After Administration for Non-Hodgkin's Lymphoma
The incidence of cancer in 2023 is estimated at 433136 cases, according to INCa. Haemopathies account for 12% of these new cases of cancer cases of cancer, and around two-thirds are lymphoid haemopathies, in particular lymphomas.
- Conditions
- Fatigue Symptom, Lymphoma Non-Hodgkin, Chimeric Antigen Receptor T-cell Therapy, Adverse Events
- Trial name
- CAR-TIGUE (NCT06890091)
- Testing
- Fatigue assessment
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Arthritis
Determination of New Biomarkers of Septic Arthritis by Surface-Enhanced Laser Desorption/Ionization Time-Of-Flight (SELDI-TOF)
Septic arthritis is a frequent, potentially disabling and/or life-threatening disease. To diagnose a septic arthritis is a complex procedure, first because of numerous differential diagnoses (such as crystal arthritis), second…
- Trial name
- NOUBASST (NCT01010165)
- Where
- France
- Volunteers
- 89 people
- Sponsor
- University Hospital, Grenoble
Peritoneal Neoplasms, Hyperthermic Intraperitoneal Chemotherapy
Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy
Introduction Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is considered as the standard of care for the treatment of peritoneal metastases.
- Conditions
- Peritoneal Neoplasms, Hyperthermic Intraperitoneal Chemotherapy, Intraoperative Care, Fluid Therapy
- Trial name
- ALBUCHIP (NCT06351475)
- Testing
- Intra-operative albumin administration, Control
- Where
- 8 sites in France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Compare 2 Models of Midwifery Care in Maternity Care
Personalized Support Care in Alternative Midwifery Birth Units Versus Traditional Units in France : Effects on Perinatal Health and Outcomes
Most pregnancies and deliveries in France occur without complication. According to the 2016 Perinatal Survey, 2/3 of births are carried out by spontaneous vaginal delivery with midwife support in most cases.
- Trial name
- PhysioCare (NCT05483101)
- Testing
- Alternative birth units
- Where
- 3 sites in France
- Volunteers
- 597 people
- Sponsor
- Rennes University Hospital
Malignant Breast Tumours
3D Breast Ultrasound Elastography in Patients Under Neoadjuvant Chemotherapy
Breast Ultrasound Elastography is a complementary technique permitting a better characterization of breast lesions. 3D breast ultrasound elastography is a novel technique permitting a volumetric calculation of lesion stiffness.
- Trial name
- NCT01531036
- Testing
- 3D Ultrasound elastography by means of shear wave propagation into breast tissue
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Perennial Allergic Rhinitis (PAR)
A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)
The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in adult participants with perennial allergic rhinitis. Participants can expect study participation to last up to 29.5 months.
- Trial name
- NCT06339008
- Testing
- LY3650150, Standard therapy for INCS
- Where
- 74 sites in United States, Belgium and 4 more
- Volunteers
- 450 people
- Sponsor
- Eli Lilly and Company
Healthy
Fasting Study of Doxycycline Monohydrate Tablets 100 mg and Adoxa Tablets 100 mg
The objective of this study was to investigate the bioequivalence of Mylan's doxycycline monohydrate 100 mg tablets to Par's Adoxa® 100 mg tablets following a single, oral 100 mg (1 x 100 mg) dose administered under fasting…
- Trial name
- NCT00649571
- Testing
- Doxycycline Monohydrate Tablets (100 mg, Adoxa Tablets 100 mg
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Quality of Life
Patient-Reported Outcomes in Real-life of Cabotegravir and Rilpivirine
Context The introduction of the long-acting injectable antiretroviral treatment cabotegravir and rilpivirine into the therapeutic armamentarium for people living with HIV represents a potentially significant evolution in…
- Trial name
- PANTER (NCT06403865)
- Testing
- Cabotegravir, Rilpivirine Drug Combination
- Volunteers
- 280 people
- Sponsor
- University Paris 7 - Denis Diderot
Type 1 Diabetes Mellitus
Web-Based Follow-Up Using Cellular Phone in Type 1 Diabetic Patients Under Insulin Pump Therapy : The PumpNet Study
The purpose of this study is to determine if telecare using modern telecommunication devices can improve the metabolic control and the quality of life of type 1 diabetic patients.
- Trial name
- NCT00324584
- Testing
- Telemonitoring of glucose values using GlucoNet device
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Perennial Allergic Rhinitis
Long Term Safety and Efficacy of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Perennial Allergic Rhinitis (PAR)
To evaluate the long term safety and efficacy of GSP 301 NS compared to 2 placebo NS formulations for the treatment of perennial allergic rhinitis (subjects 12 years of age and older)
- Trial name
- GSP 301-303 (NCT02709538)
- Testing
- GSP 301 NS
- Where
- 34 sites in United States
- Volunteers
- 601 people
- Sponsor
- Glenmark Specialty S.A.
Perennial Allergic Rhinitis, Allergic Rhinitis
Safety and Effectiveness of Ciclesonide Nasal Spray in Patients With Perennial Allergic Rhinitis During One Year Treatment (BY9010/M1-404)
The purpose of this study is to investigate the safety and effectiveness of ciclesonide nasal spray as compared with placebo (inactive substance) nasal spray in relieving symptoms of perennial allergic rhinitis.
- Conditions
- Perennial Allergic Rhinitis, Allergic Rhinitis, Hay Fever
- Trial name
- NCT00163501
- Testing
- Ciclesonide
- Where
- 41 sites in United States
- Volunteers
- 600 people
- Sponsor
- AstraZeneca