Clinical trials: Oxygen Deficiency
Lung Diseases, Interstitial, Exercise, Compulsive
Muscles Oxygenation During Exercise in Fibrosing Interstitial Lung Diseases
The type of this study is an observational prospective study. It will be done to determine the oxygenation status of the intercostal muscles and quadriceps femoris muscle during exercise in patients with fibrosing lung and to…
- Conditions
- Lung Diseases, Interstitial, Exercise, Compulsive, Oxygen Deficiency
- Trial name
- NCT05855447
- Testing
- NIRS device usage during 6MWT, Peripheral Muscle Strength Measurement, Pulmonary Function Test
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Pulmonary Disease, Chronic Obstructive, Mitochondrial Alteration
High Intensity Interval Training and Muscle Adaptations During PR
Pulmonary rehabilitation (PR) is a validated treatment in patients with Chronic Obstructive Pulmonary Disease (COPD), improving exercise tolerance, quality of life and dyspnea.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Mitochondrial Alteration, Oxygen Deficiency
- Trial name
- MITOXITRAIN (NCT05858463)
- Testing
- Modality of exercise training
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Survival, Prosthesis, Oxygen Deficiency
Awake Prone Positioning for COVID-19 Acute Hypoxaemic Respiratory Failure
The objective of our study is to evaluate the effectiveness of prone position in preventing intubation or death in spontaneously ventilated patients with COVID-19 with acute respiratory failure.
- Trial name
- NCT05866289
- Testing
- Prone position
- Where
- Morocco
- Volunteers
- 1,069 people, healthy volunteers welcome
- Sponsor
- Mohammed VI University Hospital
Oxygen Deficiency, Oxygen Therapy
Sustainable Preservation of Essential Oxygen Resources: A Phase 4 Crossover Study of the BUFEO System: SAVE O2
The current methods of oxygen supply administer medicinal oxygen to the patient at a constant flow. Oxygen is being delivered when the patient needs it (at inhalation) and when the patient does not need it (at exhalation and at…
- Trial name
- SAVEO2 (NCT05677009)
- Testing
- BUFEO system, Standard of Care
- Where
- Colombia
- Volunteers
- 20 people
- Sponsor
- Oxfo Corporation
Pregnancy Related, Anesthesia
Pre-oxygenation With High-flow Nasal Cannula in Caesarian Section Under General Anesthesia
The investigators and other groups have demonstrated that high-flow nasal oxygen used during preoxygenation for emergency surgery is at least equally effective as preoxygenation compared to standard tight fitting mask.
- Conditions
- Pregnancy Related, Anesthesia, Oxygen Deficiency, Cesarean Section Complications
- Trial name
- PRIOROB (NCT04711317)
- Testing
- Nasal high flow oxygen
- Where
- 4 sites in Sweden
- Volunteers
- 34 people
- Sponsor
- Karolinska University Hospital
Hypotension, Surgery-Complications
The Effects of Nicardipine and Esmolol Applied for Controlled Hypotension
In this study, the effects of nicardipine and esmolol applied for controlled hypotension in rhinoplasty on hemodynamics and regional renal oxygenation will be investigated.
- Conditions
- Hypotension, Surgery-Complications, Oxygen Deficiency
- Trial name
- NCT05430724
- Testing
- Controlled hypotention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Yuzuncu Yil University
Oxygen Deficiency
Validation of the O3 Regional Somatic Tissue Oxygenation Monitor
Testing the absolute accuracy of the Masimo O3 regional oximeter in reading somatic tissue oxygenation in healthy volunteers under controlled hypoxia.
- Trial name
- NCT04584788
- Testing
- Masimo O3 Regional Oximeter
- Where
- Netherlands
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
COVID-19, Acute Respiratory Failure
Low-field Thoracic Magnetic Stimulation Increases Peripheral Oxygen Saturation Levels in COVID-19 Patients
This study aimed to present a proof-of-concept that a 30 minutes single-session of low-field thoracic magnetic stimulation (LF-ThMS) on the dorsal thorax can be employed to increase oxygen saturation (SpO2) levels in coronavirus…
- Conditions
- COVID-19, Acute Respiratory Failure, Oxygen Deficiency
- Trial name
- NCT04895267
- Testing
- Low-field thoracic magnetic stimulation (LF-ThMS)
- Where
- Mexico
- Volunteers
- 17 people
- Sponsor
- Elias Manjarrez
Oxygen Deficiency, Coronavirus Infection
Awake Proning in COVID-19 Patients With Hypoxemic Respiratory Failure
The purpose of this study is to retrospectively review clinical data to determine whether awake proning improves oxygenation in spontaneously breathing patients with COVID-19 severe hypoxemic respiratory failure.
- Trial name
- NCT04408222
- Testing
- Awake proning
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Columbia University
Corona Virus Infection, ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2
Early-initiated High Flow Oxygen Therapy vs Conventional Oxygen Therapy Among Patients With ARDS in the Course of SARS-CoV2 Pneumonia.
The aim of the study is to compare two methods of oxygen therapy in patients with acute respiratory distress syndrome in the course of SARS-CoV2 pneumonia.
- Conditions
- Corona Virus Infection, ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2, Oxygen Deficiency
- Trial name
- NCT05197686
- Testing
- Oxygen theraphy with high flow nasal cannule, Oxygen theraphy with mask with reservoir
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Pomeranian Medical University Szczecin
Diabetes Mellitus, Type 2, Oxygen Deficiency
Oxygenation Changes After 2-month Exercise in Sedentary Older Adults With Diabetes
The aim of the study is to determine the physiological evidence of how muscular and cerebral oxygenation changes link to fatigue, physical, and cognitive performance after moderate-intensity exercise in sedentary older adults…
- Trial name
- NCT04626453
- Testing
- 2-month home moderate-intensity exercise
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Oxygen Deficiency
Quantification of Clinically Relevant Drug Induced Changes in HbO2 Affinity
The presented study is an experimental in-vitro study without intervention in-vivo. The effects of nitric oxide and prostacyclins, 5-hydroxymethylfurfural and alpha-ketoglutarate, volatile anaesthetics on haemoglobin oxygen…
- Trial name
- NCT04612270
- Testing
- Venous blood collection
- Where
- Austria
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Esophageal Neoplasms, Esophagostomy Complication
Tissue Oxygen Saturation for Esophagectomy
Tissue oxygen saturation monitoring was a useful indicator of blood flow insufficiency in the gastric tube leading to anastomotic leakage during radical esophagectomy.
- Conditions
- Esophageal Neoplasms, Esophagostomy Complication, Anastomotic Leak, Oxygen Deficiency
- Trial name
- NCT04973046
- Where
- Japan
- Volunteers
- 18 people
- Sponsor
- Shizuoka Cancer Center
Ischemia, Oxygen Deficiency
Magnetic Resonance Flow Measurements of Mesenteric Arteries and Veins and Portal Vein
To determine the difference in baseline MR flow measurements and post-prandial MR flow measurements between patients diagnosed with CGI and patients not diagnosed with CGI.
- Trial name
- NCT02875600
- Testing
- Nutri Drink
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Erasmus Medical Center
Oxygen Toxicity, Oxygen Deficiency
Supplementary Oxygen in Surgical and Medical Wards Evaluated by 30-day Mortality
This study evaluates the use and effects of supplementary oxygen in surgical and medical wards on patients admitted to a hospital in the capital region of Denmark.
- Trial name
- SOSAM (NCT03625700)
- Testing
- Oxygen gas
- Where
- Denmark
- Volunteers
- 11,196 people, healthy volunteers welcome
- Sponsor
- Hannibal Troensegaard
Power, Metabolic Disturbance
Effect of 8-week Intake of 2S-hesperidin on Performance, Body Composition and Biochemicals Markers in Amateur Cyclists
This clinical study evaluates the effect of 500 mg of 2S-hesperidin for 8 weeks on performance (power generated in different metabolic zones), body composition (fat and muscle mass) and biochemical (antioxidant, inflammatory…
- Conditions
- Power, Metabolic Disturbance, Change, Body Weight, Changes Fatty
- Trial name
- HESPERFORMAN (NCT04597983)
- Testing
- 2S-hesperidin
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Oxygen Deficiency, Desaturation of Blood
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures
THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia.
- Conditions
- Oxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
- Trial name
- NCT03430206
- Testing
- High-flow nasal cannula
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Stanford University
Coronavirus Infection, Oxygen Deficiency
Prone Positioning in Spontaneously Breathing Nonintubated Covid-19 Patient: a Pilot Study
The prone position consists of placing the patient on his or her stomach with the head on the side, during sessions lasting several hours a day and could help spontaneous ventilate the patient.
- Trial name
- ProCov (NCT04344106)
- Testing
- Prone positioning
- Where
- France
- Volunteers
- 25 people
- Sponsor
- ELHARRAR Xavier
Oxygen Deficiency
Alveolar Recruitment Maneuver During Pneumoperitoneum
Alveolar recruitment maneuver had been reported of improving arterial oxygenation and pulmonary mechanics and reduce the pulmonary complications.
- Trial name
- NCT03331471
- Testing
- alveolar recruitment maneuver, conventional ventilation
- Where
- 2 sites in South Korea
- Volunteers
- 64 people
- Sponsor
- Gachon University Gil Medical Center
Intraoperative Complications, Respiratory Complication
Lower Inspiratory Oxygen Fraction for Preoxygenation
During the induction period of general anesthesia, surgical patients are inevitably experienced a short period of apnea for endotracheal intubation or other airway manipulation.
- Conditions
- Intraoperative Complications, Respiratory Complication, Oxygen Toxicity, Oxygen Deficiency
- Trial name
- NCT03665259
- Testing
- Pure oxygen group, Lower oxygen group
- Where
- Taiwan
- Volunteers
- 304 people
- Sponsor
- E-DA Hospital