Clinical trials: Oxycodone
Joint Diseases
Depot-opioids for Pre- and Postoperative Pain Relief After Primary Knee Arthroplasty.Tapentadol vs Oxycodone vs Placebo
This study will provide knowledge about the use of long-acting opioids for pain relief after primary knee arthroplasty. The investigators will compare depot tapentadol, depot oxycodone and placebo for effect on pain relief and…
- Trial name
- NCT02604446
- Testing
- Tapentadol, Oxycodone, usual pain treatment
- Where
- Norway
- Volunteers
- 134 people
- Sponsor
- St. Olavs Hospital
Pain, Postoperative, Pain Uterus
Effects of Tapentadol Versus Oxycodone After Hysterectomy.
Opioids remain the first-line drugs for the treatment of moderate to severe postoperative pain, but the use is limited by well-known side-effects, most of which are dose-dependent.
- Conditions
- Pain, Postoperative, Pain Uterus, Pain, Acute, Opioid Use
- Trial name
- NCT03314792
- Testing
- Tapentadol, Oxycodone
- Where
- Norway
- Volunteers
- 86 people
- Sponsor
- Oslo University Hospital
Opioid Analgesia
Pharmacokinetics and Safety of ORF Tablets in Pediatric Patients
The purpose of this study is to characterize the pharmacokinetics (PK) of single-dose ORF tablets in pediatric patients aged 6 to 16 years, inclusive.
- Trial name
- NCT01160614
- Testing
- Oxycodone hydrochloride controlled-release (ORF) tablets
- Where
- 17 sites in United States, Australia and 2 more
- Volunteers
- 30 people
- Sponsor
- Purdue Pharma LP
Prostate Cancer, Pain Cancer
Determining the Effect of Abiraterone on the Metabolism of Oxycodone in Men With Prostate Cancer (the ENABLE Study)
Prostate cancer often leads to bone metastases, which require adequate pain management with opioids such as oxycodone. This study investigates whether abiraterone - a drug used in the treatment of prostate cancer - affects the…
- Trial name
- ENABLE (NCT07001709)
- Testing
- Oxycodone oral capsule 15 mg, Abiraterone Acetate Tablets 500 mg
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- Deventer Ziekenhuis
Pruritus
Comparison of Epidural Oxycodone and Epidural Morphine
The primary objectives of this study are to compare the efficacy of pain relief between epidural oxycodone and epidural morphine for postoperative analgesia after elective caesarean section and to compare the incidence and…
- Trial name
- NCT02277678
- Testing
- Opioid administration oxycodone, Opioid administration morphine
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- KK Women's and Children's Hospital
Pain, Postoperative
Norspan Versus Oxycontin as Postoperative Painkiller to Proximal Extracapsular Fractures of the Femur
Effective treatment of pain after hip fractures is very important but difficult. It is often an old patient who has many adverse effects with the use of morphine.
- Trial name
- NCT00964808
- Testing
- Buprenorphine, Oxycodone
- Where
- Denmark
- Volunteers
- 76 people
- Sponsor
- Vejle Hospital
Surgery
Oxycodone Extended-release in the Treatment of Perioperative Pain in Patients Undergoing Orthopaedic Surgery
Inadequate control of acute postoperative pain (DAPO) brings deleterious consequences for the patient, including significant cardiovascular and respiratory complications. Apart from the human suffering that is undeniable pain.
- Trial name
- NCT02238340
- Testing
- Extended-release oxycodone, Extended- release Oxycodone, ketoprofen
- Where
- Venezuela
- Volunteers
- 40 people
- Sponsor
- Hospital Central Dr. Luis Ortega
Back Pain, Neck Pain
Cannabis Versus Oxycodone for Pain Relief
This study investigates the ability of cannabis to reduce chronic back and neck pain and to reduce sensitivity to an acute painful stimulus. Cannabis will be compared to both oxycodone and a placebo.
- Trial name
- NCT02892591
- Testing
- Cannabis, Oxycodone
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pain
Single Dose Pharmacokinetics of Egalet® Oxycodone
The purpose of the study is to evaluate the pharmacokinetic profile of different Egalet® oxycodone formulations and compare to a marketed oxycodone product.
- Trial name
- NCT00801788
- Testing
- Oxycodone hydrochloride
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Egalet Ltd
Cancer
A Study to Evaluate Efficacy and Safety of Oxycodone/Naloxone Compared to OxyContin in Korean Cancer Patients
Objectives: To prove non-inferiority of Targin compared to Oxycontin in terms of change of pain intensity 1. Primary objective: Change of pain intensity (NRS 0-10) score (average pain over 24 hours obtained each evening) within 4…
- Trial name
- TOP (NCT01313780)
- Testing
- Oxycodone/Naloxone, Oxycodone(single compound)
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Mundipharma Korea Ltd