Clinical trials: Ovulation
Ovulation
Accuracy of SPD Persona LH Assay When Compared to Ultrasound Observed Ovulation and Other Indices of Ovulation
This study will examine the performance of the Persona assays in identifying the time when risk of pregnancy is highest by comparing results to ultrasound observed ovulation and other indices of ovulation.
- Trial name
- NCT01802060
- Where
- Germany
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Gestational Age, Time to Pregnancy
A Follow-up of the Early Pregnancy Study Cohort.
Background: The purpose of the 1982 1986 North Carolina Early Pregnancy Study was to determine how often pregnancy loss occurs before women know they are pregnant.
- Conditions
- Gestational Age, Time to Pregnancy, Early Pregnancy Loss
- Trial name
- NCT01132924
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Letrozole Alone Protocol Versus Using Letrozole and HCG Protocol
Letrozole is a chemical compound, CGS 20267 which is a third-generation, nonsteroidal aromatase inhibitor. Letrozole blocks estrogen synthesis by directly affecting the hypothalamic-pituitary-ovarian axis, subsequently, increases…
- Trial name
- NCT06367712
- Testing
- Letrozole tablets
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Egymedicalpedia
Polycystic Ovary Syndrome (PCOS), Anovulatory Infertility
Clomiphene Citrate Alone Versus Clomiphene Plus Metformin as First Line Approach for the Treatment of Anovulation in Infertile Patients With Polycystic Ovary Syndrome
This study will compare the effectiveness of clomiphene citrate alone with clomiphene citrate combined with metformin for treating anovulation and infertility in women with polycystic ovary syndrome (PCOS).
- Trial name
- CC-MET PCOS T (NCT07872501)
- Testing
- Clomiphane citrate + Metformin, clomiphene citrate alone
- Where
- Pakistan
- Volunteers
- 218 people
- Sponsor
- Independent University Hospital, Pakistan
Low Dose, Progesterone
Role of Low Dose Injectable Progesterone in Triggering Ovulation
The aim of this study is to evaluate the role of low dose injectable progesterone in triggering ovulation.
- Conditions
- Low Dose, Progesterone, Triggering Ovulation
- Trial name
- NCT06928844
- Testing
- Progesterone
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- The General Authority for Teaching Hospitals and Institutes
Amenorrhea, Hypoaldosteronism
Ovarian Follicle Function in Patients With Primary Ovarian Failure
No proven therapy to restore ovarian function and fertility is available to patients with karyotypically normal spontaneous premature ovarian failure.
- Conditions
- Amenorrhea, Hypoaldosteronism, Hypogonadism, Infertility
- Trial name
- NCT00001275
- Where
- United States
- Volunteers
- 1,134 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pregnancy
Effect of Luteal Progesterone Support on Pregnancy Rates With Combined Clomid/ Gonadotropin & IUI
To determine the difference in clinical pregnancy rates with and without luteal progesterone support in a young reproductive aged population having undergone ovulation induction with combined clomiphene citrate and gonadotropin…
- Trial name
- NCT02510534
- Testing
- Menopur 150 international units, Endometrin 100 mg
- Where
- United States
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Northwest Center for Infertility and Reproductive Endocrinology
Pregnancy Prevention
Oral Levonorgestrel Plus Meloxicam, IG-002 Delays Ovulation in Normal Menstruating Women by Seven Days
This clinical trial determines if an oral medication taken within 2 days of anticipated ovulation will delay ovulation by 7 days.
- Trial name
- OVULATION (NCT05695352)
- Testing
- Levonorgestrel 1.5mg, Meloxicam 15 mg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- InnovaGyn, Inc.
PCO, Induction of Ovulation
Parameters Declaring PCO Infertile Patients Either Sensitive or Resistant to Different Doses of Clomiphene Citrate.
Polycystic ovary syndrome (PCOS) is a common endocrinological disorder seen in 6%-10% of women (Human Reproduction, 2004). It is characterized by polycystic ovaries, anovulatory cycles, and hyperandrogenism.
- Conditions
- PCO, Induction of Ovulation, Clomiphene Citrate
- Trial name
- NCT04887402
- Testing
- Clomiphene Citrate
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Infertility, Ovulation Induction
To Evaluate the Convenience, Safety and Efficacy of Follitropin Alfa Liquid Pen Compared With Follitropin Beta Liquid Pen
This was a prospective, randomised, open comparative monocentric phase IIIb study to evaluate the convenience, safety and efficacy of follitropin alfa (Gonal-f) liquid pen compared with follitropin beta (Puregon) liquid pen.
- Trial name
- NCT01081639
- Testing
- Follitropin alfa liquid formulation, Follitropin beta liquid formulation
- Volunteers
- 34 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Polycystic Ovarian Syndrome
The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)
As both medications i.e. CC and letrozole have been shown to be effective in inducing ovulation in PCOS patients, this study was performed in order to evaluate which regime (whether CC or letrozole) is the best to be used as the…
- Trial name
- NCT01577017
- Testing
- Letrozole
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Nik Hazlina
Polycystic Ovary Syndrome, Infertility, Female
The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System
A Prospective, Multicenter, Randomized, Pivotal Study of the May Health System in Transvaginal Ablation of Ovarian Tissue under Ultrasound Guidance in Women with Infertility due to Polycystic Ovary Syndrome
- Trial name
- NCT06206746
- Testing
- May Health System
- Where
- 19 sites in United States
- Volunteers
- 93 people
- Sponsor
- May Health
Salivary Amylase
Assesment of Salivary Alpha-amylase Levels Before and After Ovulation
Investigators aimed to investigate whether there is an association between ovulation and salivatory alpha amylase (sAA) activity in menstrual cycles during a month period in a group of reproductive women.
- Trial name
- NCT02664480
- Testing
- Salivary alpha-Amylases
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Polycystic Ovary Syndrome
Myoinositol, L-arginine and Chromium With Letrozole for Ovulation Induction in Polycystic Ovarian Syndrome Patients
The aim of the study is to compare and assess the efficacy of combined letrozole with myoinositol, chromium, or L-arginine in infertile women with PCOS.
- Trial name
- NCT06405243
- Testing
- Myoinositol, Chromium, l-arginine
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Infertility, IVF
Outcomes of 36 vs 38 Hour Intervals From Ovulation Trigger To Oocyte Pick-Up:A Multi-Center Randomized Controlled Trial
Women who undergo assisted reproduction technology (ART) treatment will be eligible for this study. The goal of this randomized clinical trial is to compare the outcomes of ART treatment between women who have 36 and 38 hours…
- Trial name
- NCT05803655
- Testing
- 36-hour duration between ovulation triggering and oocyte pick-up procedure, 38-hour duration between ovulation triggering and oocyte pick-up procedure
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 850 people
- Sponsor
- Koç University
Ovulation Disorder
Ovulation Double Check (Proov) Verification and Usability Testing
The Ovulation Double Check test is a Class I, 510K exempt medical device. It is manufactured and packaged in an FDA-registered and cGMP compliant facility.
- Trial name
- NCT03924440
- Testing
- Proov (Ovulation Double Check) Test
- Volunteers
- 100 people
- Sponsor
- MFB Fertility
Subfertility, Female, Ovulation Disorder
Low Dose GnRHa Early Luteal Phase Down Regulation Versus GnRHa Ultra-short Protocol for Poor Ovarian Response
The management of the poor responder patients is very difficult. Currently, there is no any standard treatment for poor responder patients.
- Trial name
- NCT02940535
- Testing
- Diphereline (Triptorelin embonate), Decapeptyl (Triptorelin), human menopausal gonadotropin
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Navy General Hospital, Beijing
Ovulation Disorder, Ovarian Cysts
The Role of Estrogen in Luteinizing Hormone Surge and Ovulation
The purpose of the study is to establish that sustained estrogen levels are the driving force for the LH surge, and are thereby necessary for ovulation to occur.
- Trial name
- NCT01999569
- Testing
- Letrozole
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Subfertility
Does Hormonal Luteal Support After Intra-uterine Insemination (IUI) Increase the Pregnancy Rate?
A randomized study to investigate if hormonal luteal support after intra-uterine insemination (IUI) in ovulation induction cycles with human menopausal gonadotropin increases the pregnancy rate
- Trial name
- NCT00700492
- Testing
- progesterone
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Spontaneous Triggering of Ovulation vs. Administration of Human Chorionic Gonadotropin in Patients Undergoing IUI
HCG Versus Spontaneous LH in Intrauterine Insemination (IUI ) Cycles
We recently reported the superiority of the natural cycle to a natural cycle controlled by the administration of human chorionic gonadotropin (hCG) for planning the frozen-thawed embryo transfer cycles, demonstrating a probable…
- Trial name
- NCT01414673
- Testing
- HCG
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel