Clinical trials: Ovulation
Type 1 Diabetes, Polycystic Ovary Syndrome
Prevalence of Hyperandrogenism in Type 1 Diabetes
The investigators aim to estimate the prevalence of functional ovarian hyperandrogenism [idiopathic hyperandrogenism, idiopatic hirsutism, and polycystic ovary syndrome (PCOS)] in adult patients with type 1 diabetes (T1DM) in an…
- Conditions
- Type 1 Diabetes, Polycystic Ovary Syndrome, Hyperandrogenism, Hirsutism
- Trial name
- NCT04979377
- Testing
- Clinical hyperandrogenism assessment, Total testosterone (ng/dL), A1c (%)
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Clinical Pregnancy Rate, Ovulation Induction
Follicular Long GnRH Agonist Versus Antagonist Protocol in PCOS Women Undergoing in Vitro Fertilization
Pituitary down regulation is widely used during in vitro fertilization (IVF) procedures. It can suppress the spontaneous luteinizing hormone (LH) surge, and can also make follicles growth evenly.
- Conditions
- Clinical Pregnancy Rate, Ovulation Induction, IVF
- Trial name
- NCT02496754
- Testing
- GnRH-a, GnRH-anta
- Where
- China
- Volunteers
- 1,266 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Polycystic Ovary Syndrome, Diminished Ovarian Reserve
Clinical Trial of Anovulatory Infertility
This project aims to study the expression of clock genes and related proteins in follicular fluid and granulosa cells, depicting the periodic, amplitude, and phase changes of biological clock genes and related proteins in women…
- Conditions
- Polycystic Ovary Syndrome, Diminished Ovarian Reserve, Ovulation Disorder
- Trial name
- NCT06601452
- Testing
- a compound prescription of Chinese medicine
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nanjing University of Chinese Medicine
Ovulation, Menstruation
Impact of Menstrual Phase on Oral Glucose Sensitivity
In this study we are determining whether the hormones associated with the phases of the menstrual cycle (menstruation \& ovulation) influence taste sensitivity to glucose.
- Trial name
- NCT06800690
- Testing
- Urinary Estrogen Level
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Menstruation, Ovulation
Menstrual Cycle Study
A data collection study to develop algorithms to estimate menstrual cycle phases.
- Trial name
- NCT05999123
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Fitbit LLC
Ovulation, Ovulation Inhibition
Can Ibuprofen Delay Ovulation in Natural Cycle-IVF?
During natural cycle in vitro fertilisation, no gonadotropin stimulation is used to stimulate oocyte production. Ovulation is induced with HCG (human chorionic gonadotropin) and the follicle is retrieved 36 hours later.
- Conditions
- Ovulation, Ovulation Inhibition, Ovulation Inhibition/Drug Effects, Pregnancy
- Trial name
- Ibudelay (NCT02571543)
- Testing
- Ibuprofen
- Where
- Switzerland
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Menstrual Cycle, Ovulation
Sensor Technology Assessments of Reproductive Target Study
The objective of this study was to better understand female reproductive health in the context of using wearable technology. Participants were provided and wore an Oura Ring, tracked their menstrual cycles, provided at-home…
- Conditions
- Menstrual Cycle, Ovulation, Menstruation
- Trial name
- START (NCT06142097)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Ouraring Inc.
Polycystic Ovary Syndrome, Ovulation Disorder
Clusterin Level and Polycystic Ovary Syndrome
Clusterin, a protein involved in metabolic syndrome, insulin resistance, and metabolic disorders associated with inflammation and oxidative stress such as atherosclerosis, Alzheimer's and some malignancies, has elevated levels in…
- Trial name
- NCT06601725
- Testing
- Clusterin level
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Menstrual Cycle, Ovulation
Apple Women's Health Study
This is an observational longitudinal study to advance the understanding of menstrual cycle and gynecologic health conditions including PCOS, infertility and breast cancer.The study will be hosted within the Research…
- Conditions
- Menstrual Cycle, Ovulation, Menstruation, Polycystic Ovary Syndrome
- Trial name
- NCT04196595
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Ovulation Induction
A Phase 2 Trial to Evaluate if Corifollitropin Alfa (Org 36286), Followed by a Low Daily Dose of hCG or Recombinant FSH Can Induce Monofollicular Growth in Women With WHO Group II Anovulatory Infertility (P05693)
The primary objective of this trial is to evaluate whether a corifollitropin alfa (Org 36286) regimen applying a single or repeated dose of corifollitropin alfa followed by a low daily dose of Human Chorion Gonadotropin (hCG) or…
- Trial name
- NCT00697255
- Testing
- corifollitropin alfa, recombinant Follicle Stimulating Hormone (recFSH), human Chorion Gonadotropin (hCG)
- Volunteers
- 8 people
- Sponsor
- Organon and Co
Ovulation Disorder
Three Dimensional Ultrasonographic Detection of Human Ovulation
The research aims to compare diagnosis of ovulation and anovulation in 2D and 3D ultrasonography.
- Trial name
- NCT06433453
- Testing
- Indomethacin 50 MG, Transvaginal ultrasound scans, Finger prick blood test
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Ovulation Disorder
Ovulation Double Check (Proov) Verification and Usability Testing
The Ovulation Double Check test is a Class I, 510K exempt medical device. It is manufactured and packaged in an FDA-registered and cGMP compliant facility.
- Trial name
- NCT03924440
- Testing
- Proov (Ovulation Double Check) Test
- Volunteers
- 100 people
- Sponsor
- MFB Fertility
IVF, Infertility, Female
Inhibin B/AFC Ratio for Ovarian Response
Ovarian response to gonadotropin stimulation plays a major role in the success of in vitro fertilization (IVF). Anti-müllerian hormone (AMH), inhibin B, and antral follicle count (AFC) are ovarian reserve markers and also…
- Conditions
- IVF, Infertility, Female, Ovulation Disorder
- Trial name
- NCT06292806
- Testing
- FSH-R
- Volunteers
- 144 people
- Sponsor
- Insemine Humen Reproduction Centre
Poor Response to Ovulation Induction
Effect of LH Supplementation on the Endometrial Gene Expression Profile in Poor Ovarian Responders
This is a prospective randomized open-label cross-over study. Poor responder patients will undergo two ovarian stimulation cycles.
- Trial name
- NCT05405686
- Testing
- Lutropin alfa, Follitropin alfa, Endometrial biopsy
- Sponsor
- CRG UZ Brussel
Female Subjects Undergoing COH in ART to Prevent Early Ovulation
Identify Effective Doses of SHR7280 Tablets in Controlled Ovarian Hyperstimulation (COH) for Female Subjects Undergoing Assisted Reproductive Technology (ART)
This study is a multicentre, open-label phase II dose-finding clinical trial that will recruit approximately 120 female subjects undergoing COH for in vitro fertilization (IVF) or intracytoplasmic single sperm injection (ICSI).
- Trial name
- NCT05082233
- Testing
- SHR7280 tablets
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Sub Fertility, Female, Fertility Disorders
Feasibility and Safety of Fasting in Fertility Treatment
This exploratory study investigates fasting as a potential supportive therapy in infertility treatment for women suffering from infertility
- Conditions
- Sub Fertility, Female, Fertility Disorders, Cycle Disorders Menstrual, Ovulation Disorder
- Trial name
- KiWuA (NCT04942457)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Charite University, Berlin, Germany
Poor Response to Ovulation Induction
A Prospective Observational Study of Biomarkers for a Personalised IVF Treatment
Study investigates the effect of four-dimensional patient data (medical, lifestyle, environmental, and genetic) on the outcomes of ovarian stimulation for IVF.
- Trial name
- NAITIVE (NCT05780632)
- Where
- Czechia
- Volunteers
- 500 people
- Sponsor
- Cognitive IVF a.s.
Polycystic Ovary Syndrome, Puberty Disorders
Does Treatment of Androgen Excess Using Spironolactone Improve Ovulatory Rates in Girls With Androgen Excess?
Adolescent girls with androgen excess have a higher rate of irregular periods and decreased ovulation rates compared to normal girls, and are considered at-risk for developing polycystic ovary syndrome (PCOS).
- Conditions
- Polycystic Ovary Syndrome, Puberty Disorders, Ovulation Disorder
- Trial name
- CBS009 (NCT04075149)
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Warm Needling, Electroacupuncture
Clinical Observation of Warm Needling Combined With and Electroacupuncture Therapy on Ovulatory Dysfunction
To observe the effect of warm needling combined with electroacupuncture on the ovulation promotion rate and pregnancy rate in luteinized unruptured follicle syndrome (LUFS).
- Conditions
- Warm Needling, Electroacupuncture, Ovulation Dysfunction
- Trial name
- NCT05874518
- Testing
- warm needling combined with electroacupuncture, The treatment with letrozole tablets was started on the fifth day of the menstrual cycle
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Liuzhou Maternity and Child Healthcare Hospital
Poor Response to Ovulation Induction
Ovarian Response in Oocyte Donors Triggered With GnRH Agonists
The use of agonist of GnRH (aGnRH) trigger to avoid ovarian hyperstimulation syndrome is nowadays widely used. The action of the aGnRH in the hypophysis triggers an LH and FSH surge, which mimicks the natural surge that occurs in…
- Trial name
- NCT05109403
- Where
- Spain
- Volunteers
- 224 people
- Sponsor
- Clínica EUGIN