Clinical trials: Ovulation
Reproduction
Evaluation of EarlySense for Monitoring Ovulation Cycles and Detection of Early Stages of Pregnancy in Home Environment
The study objective is to collect data to assess the accuracy and reliability of Earlysense fertility cycle monitoring performance vs.
- Trial name
- NCT02634359
- Testing
- EarlySense home device, Vaginal ultrasound, Blood Test
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- EarlySense Ltd.
Infertility
Letrozole vs. Clomiphene Citrate in Patients With Anovulatory Infertility
OBJECTIVE: To compare the effectiveness of letrozole and clomiphene citrate (CC) in patients with anovulatory infertility. DESIGN: Open, prospective, randomized, parallel group, multicentric, comparative trial.
- Trial name
- NCT00610077
- Testing
- Letrozole, Clomiphene citrate
- Where
- India
- Volunteers
- 55 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Fertility
Kegg Fertility Study
Fertility Awareness Based Methods (FABMs), such as calendar tracking, basal body temperature (BBT), and monitoring cervical mucus, are widely used but may have limitations in accurately detecting the complete fertility window.
- Trial name
- CMTrak-US (NCT06862440)
- Testing
- Kegg
- Where
- United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Lady Technologies Inc
Ovulation Induction, Infertility
An Open Label, Canadian Phase IIIb Study With Ovidrel in Ovulation Induction (OI) and Assisted Reproductive Technique (ART)
With the development of the recombinant gonadotrophins, the use of human source proteins for the production of hormones has become unnecessary.
- Trial name
- NCT01152866
- Testing
- Choriogonadotropin alpha (r-hCG)
- Volunteers
- 3 people
- Sponsor
- EMD Serono
Pregnancy
Connected Ovulation Test Efficacy Study
Clearblue Connected Ovulation Test System (COTS) has been designed for home use by women who are either planning or trying for a pregnancy.
- Trial name
- NCT03424590
- Testing
- Clearblue Connected Ovulation Test System
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Pregnancy, Neonates
Pregnancy and Neonatal Follow-up of Ongoing Pregnancies Established in Clinical Trial P05693 (P05713)
The objective of follow-up study P05713 is to evaluate whether corifollitropin alfa (Org 36286) treatment for the induction of monofollicular growth in women who underwent ovulation induction (OI) in base study P05693…
- Trial name
- Care (NCT00702338)
- Testing
- corifollitropin alfa, recombinant Follicle Stimulating Hormone (recFSH), human Chorion Gonadotropin (hCG)
- Volunteers
- 1 people
- Sponsor
- Organon and Co
Menstruation, Ovulation
Menstrual Cycle Study
A data collection study to develop algorithms to estimate menstrual cycle phases.
- Trial name
- NCT05999123
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Fitbit LLC
IVF, Infertility
Second Ovulation Induction
Studies reported various risk factors for inadequate ovulation induction such as body mass index, low ovarian reserve, low baseline FSH and LH, and previous use of contraception or agonist.
- Trial name
- NCT06502665
- Testing
- Women having had second ovulation induction after failed oocyte pick-up
- Where
- Canada
- Volunteers
- 87 people
- Sponsor
- Clinique Ovo
Ovulation
Accuracy of SPD Persona LH Assay When Compared to Ultrasound Observed Ovulation and Other Indices of Ovulation
This study will examine the performance of the Persona assays in identifying the time when risk of pregnancy is highest by comparing results to ultrasound observed ovulation and other indices of ovulation.
- Trial name
- NCT01802060
- Where
- Germany
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Letrozole Alone Protocol Versus Using Letrozole and HCG Protocol
Letrozole is a chemical compound, CGS 20267 which is a third-generation, nonsteroidal aromatase inhibitor. Letrozole blocks estrogen synthesis by directly affecting the hypothalamic-pituitary-ovarian axis, subsequently, increases…
- Trial name
- NCT06367712
- Testing
- Letrozole tablets
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Egymedicalpedia
Infertility, Ovulation Induction
To Evaluate the Convenience, Safety and Efficacy of Follitropin Alfa Liquid Pen Compared With Follitropin Beta Liquid Pen
This was a prospective, randomised, open comparative monocentric phase IIIb study to evaluate the convenience, safety and efficacy of follitropin alfa (Gonal-f) liquid pen compared with follitropin beta (Puregon) liquid pen.
- Trial name
- NCT01081639
- Testing
- Follitropin alfa liquid formulation, Follitropin beta liquid formulation
- Volunteers
- 34 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Polycystic Ovary Syndrome, Infertility, Female
The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System
A Prospective, Multicenter, Randomized, Pivotal Study of the May Health System in Transvaginal Ablation of Ovarian Tissue under Ultrasound Guidance in Women with Infertility due to Polycystic Ovary Syndrome
- Trial name
- NCT06206746
- Testing
- May Health System
- Where
- 19 sites in United States
- Volunteers
- 93 people
- Sponsor
- May Health
Ovulation Disorder
Ovulation Double Check (Proov) Verification and Usability Testing
The Ovulation Double Check test is a Class I, 510K exempt medical device. It is manufactured and packaged in an FDA-registered and cGMP compliant facility.
- Trial name
- NCT03924440
- Testing
- Proov (Ovulation Double Check) Test
- Volunteers
- 100 people
- Sponsor
- MFB Fertility
Infertile Female Subjects Undergoing Controlled Ovarian Hyperstimulation to Suppress Premature LH Surge and Prevent Early Ovulation
To Compare the Efficacy and Safety of Oral SHR 7280 Tablets With Ganirelix Acetate Injection in Infertile Female Subjects
This study is a multi-center, randomized, double-blind, positive drug-controlled, non-inferiority Phase III clinical trial. The study will enroll approximately 316 infertile female subjects undergoing controlled ovarian…
- Trial name
- NCT05994378
- Testing
- SHR7280；Ganirelix Acetate Injection simulant, SHR7280 simulant； Ganirelix Acetate Injection
- Where
- China
- Volunteers
- 317 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Infertility
A Phase 3b Study to Evaluate Subject Satisfaction With Follitropin Alfa Injection in Oligoanovulatory Infertile Women Undergoing Ovulation Induction
This is a prospective, open-label, multicenter, trial evaluating subject satisfaction and efficacy with follitropin alfa injection applied by Pen device compared with the subject's previous experience with injectable…
- Trial name
- NCT00230815
- Testing
- Follitropin alfa injected by Pen device, Recombinant Human Choriogonadotropin (r-hCG)
- Volunteers
- 62 people
- Sponsor
- EMD Serono
Ovulation Induction
AS900672-Enriched in Ovulation Induction
This is a Phase 2, interventional, multi-center, randomized, assessor-blind, active-comparator, dose-finding study to evaluate a new investigational long-acting follicle stimulating hormone (FSH) in oligo-anovulatory women…
- Trial name
- NCT00553514
- Testing
- AS900672-Enriched 10 microgram (mcg), AS900672-Enriched 20 mcg, AS900672-Enriched 30 mcg
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Pregnancy, Fertility
Home Ovulation Test One Cycle at Home Study
This study will assess the usability of a Home Ovulation Test when used at home by lay-users seeking to conceive.
- Trial name
- NCT04667858
- Testing
- Home Ovulation Test
- Where
- United Kingdom
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Infertility, Monofollicular Development
Low-dose Gonal-f® in Ovulation Induction
This is a prospective, multicenter, open-label, comparative and parallel-group study of ovulation induction evaluating tailoring of Recombinant follicle stimulating hormone (FSH) treatment using the Gonal-f® prefilled pen in…
- Trial name
- LoGo (NCT01871532)
- Testing
- Gonal-f®
- Where
- 10 sites in Ireland, United Kingdom
- Volunteers
- 24 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Polycystic Ovary Syndrome
Combination Letrozole and Clomiphene Citrate Versus Letrozole Alone
Clomiphene citrate is a non-steroidal triphenylethylene derivative distantly related to diethylstilbestrol. It acts as a selective estrogen receptor modulator (SERM), similar to tamoxifen and raloxifene.
- Trial name
- NCT06507332
- Testing
- Letrozole 2.5mg
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Egymedicalpedia
Contraception
US Ovulation Inhibition Study in Obese Women
Birth Control Patch Study
- Trial name
- NCT00873483
- Testing
- Ethinylestradiol/Gestodene (BAY86-5016)
- Where
- 6 sites in United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Bayer