Clinical trials: Overweight or Obese Participants Without Diabetes
Overweight, Obese
A Study of CT-868 in Type 1 Diabetes Mellitus
This study will evaluate the changes in glycemic control in overweight and obese adults with Type 1 Diabetes Mellitus after receiving CT-868 for 16 weeks. The effectiveness and safety of CT-868 will be compared to placebo.
- Conditions
- Overweight, Obese, Type 1 Diabetes Mellitus
- Trial name
- NCT06062069
- Testing
- CT-868, CT-868 Pen Injector
- Where
- 22 sites in United States
- Volunteers
- 111 people
- Sponsor
- Carmot Therapeutics, Inc.
Obesity, Overweight
The Influence of Physical Activity on the Gut Microbiome of Pre-Diabetic Adults
The present study is a 100-participant randomized controlled 2-arm parallel trial that employs a metagenomic approach to examine how 8 weeks of supervised moderate-intensity treadmill walking exercise (MWE) for 30-45 min 3…
- Conditions
- Obesity, Overweight, Overweight and Obesity, PreDiabetes
- Trial name
- NCT04931836
- Testing
- Physical Activity Intervention
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- University of Minnesota
Obese With Comorbidities, Overweight With Comorbidities
Study for Multiple Doses of HM15136(Efpegerglucagon) in Obese or Overweight Subjects With Comorbidities
The planned period of each cohort is 22 weeks including subject screening, treatments for 12 weeks, and follow up period.
- Conditions
- Obese With Comorbidities, Overweight With Comorbidities, Type2 Diabetes
- Trial name
- NCT04167553
- Testing
- HM15136
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Type 2 Diabetes Mellitus, Obese
Ox Bile- Conjugated Bile Acids Sodium in Type II Diabetes Mellitus
To study the effect of an ileocolonic formulation of ox bile extract on insulin sensitivity, postprandial glycemia and incretin levels, gastric emptying, body weight and fasting serum FGF-19 (fibroblast growth factor) levels in…
- Conditions
- Type 2 Diabetes Mellitus, Obese, Overweight
- Trial name
- NCT02871882
- Testing
- Gastric Emptying test, Mixed Oral Glucose Tolerance test, Conjugated bile acids sodium
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Pre-diabetes, Overweight
Fit and Trim for Diabetes Prevention
Filipino Americans (FA) are the second largest (3.4 million) Asian group in the US. and have one of the highest prevalences of obesity and type 2 diabetes mellitus compared to non-Hispanic whites, African Americans and Hispanics.
- Conditions
- Pre-diabetes, Overweight, Obese
- Trial name
- NCT02278939
- Testing
- Filipinos Fit and Trim Weight Loss Program
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Overweight, Obese
Angiotensin II Blockade and Inflammation in Obesity
Overweight and obesity, which afflicts ~65% of the U.S. population and more than 1 billion people worldwide, increases the risk of developing hypertension.
- Conditions
- Overweight, Obese, Prehypertension, Hypertension
- Trial name
- ARB (NCT01684748)
- Testing
- Olmesartan medoxomil
- Volunteers
- 20 people
- Sponsor
- Virginia Polytechnic Institute and State University