Clinical trials: Overactive Bladder, open to volunteers
Chronic Kidney Disease, Overactive Bladder
Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly
This study focuses on Beijing community residents aged 60 and above, aiming to understand how urinary function (like bladder or kidney function) and multiple health problems (such as high blood pressure, diabetes) affect each…
- Conditions
- Chronic Kidney Disease, Overactive Bladder, Benign Prostatic Hyperplasia, Female Pelvic Floor Dysfunction
- Trial name
- UFMR-BE (NCT07357714)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Cervical Carcinoma, Endometrial Carcinoma
Flyte Device for Improving Urinary Incontinence Among Endometrial and Cervical Cancer Survivors Who Have Undergone Radiation Therapy
This clinical trial studies how well and how easy it is to use a device called Flyte in improving problems with bladder control (urinary incontinence) among endometrial and cervical cancer survivors who have undergone radiation…
- Conditions
- Cervical Carcinoma, Endometrial Carcinoma, Overactive Bladder, Voiding Disorders
- Trial name
- NCT07662824
- Testing
- Educational Intervention, Interview, Flyte Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Mayo Clinic
Overactive Bladder Syndrome
Impact of TTNS on Bladder Symptoms Among People With MS, A RCT
Background: Neurogenic lower urinary tract dysfunction is common among people with multiple sclerosis (MS). Recent studies showed that bladder storage symptoms are predominant among MS with a pooled prevalence of frequency at…
- Trial name
- NCT06341673
- Testing
- Active Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Saudi Arabia
- Volunteers
- 72 people
- Sponsor
- Hawra Al-Dandan
Radiation Exposure, Overactive Bladder
Fluoroscopy Radiation Reduction During Sacral Neuromodulation Lead Placement
Fluoroscopy is performed when placing a lead during a sacral neuromodulation procedure. During lead placement, subjects will receive either conventional or experimental fluoroscopic settings.
- Conditions
- Radiation Exposure, Overactive Bladder, Urge Incontinence, Urgency-frequency Syndrome
- Trial name
- NCT04527445
- Testing
- Reduced radiation fluoroscopy, Conventional fluoroscopy
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Loma Linda University
Overactive Bladder Syndrome
Efficacy and Safety of Peroneal Electric Transcutaneous Neuromodulation in the Real-world Clinical Practice
The aim of the project is to study neuromodulation treatment in patients with idiopathic overactive bladder syndrome (OAB) in real clinical practice.
- Trial name
- NCT07796958
- Testing
- Peroneal eTNM
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- University Hospital Ostrava
Urinary Incontinence in Children
Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)
The primary objective is to evaluate if (1) combination therapy of solifenacin and mirabegron in low doses is superior to monotherapy of solifenacin in high dose and if (2) combination therapy of mirabegron and solifenacin in low…
- Trial name
- NCT06551246
- Testing
- Solifenacin, Mirabegron
- Where
- 5 sites in Denmark
- Volunteers
- 236 people
- Sponsor
- University of Aarhus
Urinary Incontinence, Urinary Incontinence, Urge
Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD)
UCon is a medical device for treatment of the symptoms of overactive bladder (OAB) and bowel dysfunction (BD). It electrically stimulates the DGN through the skin to obtain modulated behaviour of the bladder/bowel musculature…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Fecal Incontinence, Fecal Incontinence With Fecal Urgency
- Trial name
- NCT06091566
- Testing
- UCon-Bar
- Where
- 3 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- InnoCon Medical
Overactive Bladder (OAB)
Burden and Efficacy of Anticholinergic vs Mirabegron in Overactive Bladder - A Randomized Controlled Study
Overactive bladder (OAB) is a common condition that causes a sudden, strong need to urinate, often with frequent daytime and night-time trips to the toilet, and sometimes leaking.
- Trial name
- BEAM (NCT07711808)
- Testing
- Solifencin, Mirabegron
- Volunteers
- 208 people
- Sponsor
- Universidade do Porto
Overactive Bladder, Urinary Urgency Incontinence
Sacral Neuromodulation for Male Overactive Bladder (MOAB)
To assess the post-market clinical outcomes of the Axonics SNM System for treatment of overactive bladder in male patients.
- Conditions
- Overactive Bladder, Urinary Urgency Incontinence, Benign Prostatic Hyperplasia, Prostate Cancer
- Trial name
- NCT06511141
- Testing
- Axonics SNM System
- Where
- 23 sites in United States
- Volunteers
- 150 people
- Sponsor
- Axonics, Inc.
Overactive Bladder, Urge Incontinence
A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)
A prospective, multicenter, single-arm study to evaluate the safety and effectiveness of the eCoin® implanted tibial nerve stimulator in subjects with urgency urinary incontinence (UUI).
- Conditions
- Overactive Bladder, Urge Incontinence, Incontinence, Urinary, Urinary Urge Incontinence
- Trial name
- RECIPE (NCT05685433)
- Testing
- eCoin Tibial Nerve Stimulation
- Where
- 22 sites in United States
- Volunteers
- 200 people
- Sponsor
- Valencia Technologies Corporation
Overactive Bladder, Overactive Bladder (OAB)
Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women
The goal of this clinical trial is to learn if a vaginal radiofrequency (RF) device called MORPHEUSV works to treat overactive bladder (OAB) in women. Researchers also want to learn how safe the device is for this indication.
- Conditions
- Overactive Bladder, Overactive Bladder (OAB), Urge Urinary Incontinence, Mixed Urinary Incontinence (Urge-Predominant)
- Trial name
- DENARA (NCT07209397)
- Testing
- Detrusor nerve radiofrequency ablation
- Where
- 9 sites in United States
- Volunteers
- 202 people
- Sponsor
- InMode MD Ltd.
Overactive Bladder (OAB)
Tensi+ for Treating Overactive Bladder
The purpose of the study is to evaluate the safety and effectiveness of the Tensi+ device using Transcutaneous Posterior Tibial Nerve Stimulation (TPTNS) for treating patients suffering from OAB symptoms urinary frequency…
- Trial name
- NCT07300904
- Testing
- Tensi+
- Where
- 3 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Stimuli Technology
Dry AMD, Overactive Bladder
Mirabegron in Patients With Age-Related Macular Degeneration
The goal of this clinical trial is to learn if Mirabegron works to treat dry AMD in patients, aged between 50 and 80 years-old, with early or moderate dry AMD and overactive bladder.
- Trial name
- NCT07305298
- Testing
- Mirabegron 50mg, Solifenacin 5mg
- Where
- Italy
- Volunteers
- 312 people
- Sponsor
- University of Naples
Multiple Sclerosis
Effect of High Tone Power Therapy on Bladder Disturbance
This study is conducted to investigate the effect of high-tone power therapy on improving bladder function and quality of life in patients with MS.
- Trial name
- NCT06837675
- Testing
- high tone power therapy, selected physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Overactive Bladder, Bladder Pain Syndrome
Bladder Botox UTI Antibiotic Prophylaxis
Overactive bladder (OAB) is a common condition with a prevalence of 17% in the general population that significantly affects quality of life.
- Trial name
- NCT06387329
- Testing
- Nitrofurantoin 100 MG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Stroke, Overactive Bladder (OAB)
Efficacy of Transcutaneous Electrical Stimulation Therapy in the Treatment of Overactive Bladder Developing After Stroke
This study is a prospective, randomized controlled clinical trial designed to evaluate the efficacy of transcutaneous electrical stimulation (posterior tibial nerve stimulation, PTNS) in the treatment of overactive bladder (OAB)…
- Conditions
- Stroke, Overactive Bladder (OAB), Tibial Nerve
- Trial name
- NCT07740668
- Testing
- posterior tibial nerve stimulation, PTNS
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kutahya Health Sciences University
Spinal Cord Injuries (SCI), Detrusor Overactivity
The Effectiveness of Transcutaneous Sacral Neuromodulation Techniques-Magnetic Stimulation and Electrical Stimulation-on Detrusor Overactivity in Patients With Spinal Cord Injury
The goal of this prospective, randomized clinical trial is to compare the efficacy and safety of transcutaneous sacral magnetic stimulation versus sacral electrical stimulation for detrusor overactivity in 40 male and female…
- Trial name
- NCT07578532
- Testing
- Transcutaneous Sacral Electrical Stimulation, Transcutaneous sacral magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara City Hospital Bilkent
Overactive Bladder
Tensi+ European Post-Market Clinical Follow-Up
Tensi+ (Stimuli Technology, Boulogne Billancourt, France) is a newly released, medical transcutaneous-posterior tibial nerve stimulation (TC-pTNS) device marketed for overactive bladder (OAB) management.
- Trial name
- NCT07205445
- Testing
- Tensi+
- Where
- 17 sites in France, Italy and 1 more
- Volunteers
- 500 people
- Sponsor
- Stimuli Technology
Bladder Dysfunction, Overactive Bladder
Noninvasive Ultrasound Assessment of Detrusor Dysfunction
The purpose of this study is to test a new ultrasound method called Quantitative Ultrasound Bladder Vibrometry to detect abnormal bladder function.
- Conditions
- Bladder Dysfunction, Overactive Bladder, BPH With Urinary Obstruction
- Trial name
- NUADD (NCT05652023)
- Where
- United States
- Volunteers
- 2,023 people
- Sponsor
- Mayo Clinic
Over Active Bladder, Urinary Incontinence (UI)
Electroacupuncture as a Treatment for Refractory Overactive Bladder
This study is a single-site feasibility randomised controlled trial evaluating the feasibility and acceptability of electroacupuncture (EA), and percutaneous tibial nerve stimulation (PTNS), in women with refractory overactive…
- Conditions
- Over Active Bladder, Urinary Incontinence (UI), Nocturia
- Trial name
- EAOAB (NCT07124390)
- Testing
- Name: Electroacupuncture (EA) Type: Device-based acupuncture therapy, Neuromodulation therapy
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust