Clinical trials: Overactive Bladder
Overactive Bladder Syndrome
Effectiveness of a Structured Intervention to Optimize the Use of Mirabegron
This study was a multicentre, quasi-experimental design, controlled, before-and-after trial to estimate the effectiveness related to the review of mirabegron use and, if appropriate, its discontinuation.
- Trial name
- NCT03536494
- Testing
- Review the use of mirabegron and its discontinuation
- Volunteers
- 1,932 people
- Sponsor
- Catalan Institute of Health
Urogynaecology
A Study of the Effect of Antibiotics on the Microbiology of the Bladder in Patients With Overactive Bladder
The concept of organisms living on or in the human body without causing overt signs of an infection is common in medicine and has been termed a microbiome.
- Trial name
- NCT02536872
- Testing
- None - this is a prospective observational study. Patients will be prescribed their usual treatment (antibiotics) and the effect on urine studied
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Medway NHS Foundation Trust
Overactive Bladder, Urge Incontinence
Effects of Transcutaneous and Percutaneous PTNS on Idiopathic OAB
The purpose of this study is to determine if Transcutaneous Tibial Nerve Stimulation (TENS) is as effective as Percutaneous Tibial Nerve Stimulation (PTNS) as therapeutic option for subjects with Idiopathic Overactive Bladder…
- Conditions
- Overactive Bladder, Urge Incontinence, Overactive Detrusor
- Trial name
- NCT02657057
- Testing
- PTNS, TENS SNS
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Instituto Médico Tecnológico SL
Overactive Bladder, Benign Prostatic Hyperplasia
Combination Treatment With Doxazosin Plus TolterodineSR 2 mg Versus 4mg in Men With an Overactive Bladder (OAB) and Benign Prostatic Hyperplasia (BPH)
OAB occurs in approximately 50% to 75% of men with BPO and up to 38% of men with BPO continue to suffer from OAB after relief the obstruction.Symptoms of OAB are more bothersome than the voiding complaints of slow stream and…
- Trial name
- NCT00922506
- Testing
- doxazosin plus tolterodine SR
- Where
- South Korea
- Volunteers
- 83 people
- Sponsor
- Samsung Medical Center
Urinary Incontinence, Urinary Retention
Codesign of an Optical Device to Measure Urine Flow and Volume
The study is seeking to understand the needs of patients and healthcare practitioners for an innovation in the way that changes in bladder function are assessed.
- Conditions
- Urinary Incontinence, Urinary Retention, Urinary Tract Infections, Overactive Bladder
- Trial name
- NCT05576311
- Testing
- Focus Group
- Volunteers
- 45 people
- Sponsor
- Teesside University
Stress Urinary Incontinence
Factors Affecting the Cure of Overactive Bladder Syndrome in Women Underwent Mid-urethral Sling Procedure
We will estimate the incidence of patients with overactive bladder syndrome after surgery and explore related predictors.
- Trial name
- NCT04412928
- Testing
- mid-urethral sling procedure
- Where
- Taiwan
- Volunteers
- 591 people
- Sponsor
- Far Eastern Memorial Hospital
Overactive Bladder (OAB), Detrusor Overactivity
Bladder Training With or Without Biofeedback-Assisted Pelvic Floor Muscle Training for Women With Wet Overactive Bladder
Overactive bladder causes a sudden and difficult-to-control need to urinate and may be accompanied by urine leakage. Bladder training is commonly used as a first-line treatment.
- Conditions
- Overactive Bladder (OAB), Detrusor Overactivity, Urgency Urinary Incontinence
- Trial name
- NCT07728747
- Testing
- Bladder Training, EMG Biofeedback-Assisted Pelvic Floor Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Gaziantep Islam Science and Technology University
Overactive Bladder and Urge Urinary Incontinence
The New Possibility of Treating Overactive Bladder With Radiofrequency
A prospective, randomized, single-blind, placebo-controlled study was conducted from June 2023 to May 2025. The study enrolled 95 women (N=48 in the study group; N=47 in the placebo group) who presented with confirmed symptoms of…
- Trial name
- RF and OAB (NCT07398014)
- Testing
- radiofrequency - TECAR
- Where
- Slovenia
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University Maribor
Urinary Incontinence, Urinary Obstruction
NXT Post-Market Clinical Follow-up
NXT Urodynamics System Post-Market Clinical Follow-up Clinical Investigation to Confirm Ongoing Safety and Performance in Urodynamic Patient Sub-Populations
- Conditions
- Urinary Incontinence, Urinary Obstruction, Urinary Bladder, Overactive, Urinary Bladder, Neurogenic
- Trial name
- NCT06336304
- Testing
- Urodynamic procedure
- Where
- 5 sites in United States
- Volunteers
- 163 people
- Sponsor
- Laborie Medical Technologies Inc.
Urinary Retention and Symptoms of Overactive Bladder (Urge, Frequency)
A Cost Analysis of Interstim Therapy
A study to examine the impact that Interstim Therapy for Urinary Control has on health care utilization and costs within a health care system and the satisfaction with treatment expressed by patients using this therapy.
- Trial name
- NCT00200031
- Testing
- Interstim therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- MedtronicNeuro
Overactive Bladder
A Study Of Efficacy And Safety Of Fesoterodine In Vulnerable Elderly Subjects With Overactive Bladder
This study is designed to assess the efficacy and safety of a flexible dose regimen of fesoterodine on urgency urinary incontinence (UUI) episodes in vulnerable elderly subjects with overactive bladder (OAB).
- Trial name
- NCT00928070
- Testing
- Fesoterodine
- Where
- 125 sites in United States
- Volunteers
- 566 people
- Sponsor
- Pfizer
Urinary Bladder, Overactive
FemPulse Therapy for Overactive Bladder in Women
The purpose of this clinical trial is to investigate a new medical device treatment for Overactive Bladder (OAB) in women.
- Trial name
- EVANESCE-OAB (NCT03784170)
- Testing
- FemPulse System
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- FemPulse Corporation
Overactive Bladder
Neuromodulation Implantation Settings Variation for Overactive Bladder
Participants receiving neuromodulation treatment for overactive bladder symptoms will be routinely fitted with an impulse generator.
- Trial name
- NCT02112786
- Testing
- Intermittent or Continuous Setting RestorePrime Implanted Impulse Generator
- Where
- United States
- Sponsor
- Loma Linda University
Overactive Bladder
Study to Gather Information About the Actual Use of an Adhesive Patch Placed on the Skin to Deliver Oxytrol Through the Skin Into the Bloodstream.
With this study researchers want to gather information about the consumer use behavior of Oxytrol in a simulated setting in which the medicine is sold directly to a consumer without a prescription from a healthcare professional.
- Trial name
- NCT04534491
- Testing
- Oxybutynin (Oxytrol, BAY839380)
- Where
- United States
- Volunteers
- 855 people
- Sponsor
- Bayer
Urinary Bladder, Overactive, Urinary Incontinence
Comparative Effectiveness of Initial OAB Treatment Options Among Older Women at High Risk of Falls
The goal of this study is to conduct a randomized pilot multi-arm clinical trial comparing a standard course of physical therapist provided pelvic floor muscle training (PFMT) to pharmacologic therapy for the treatment of urgency…
- Conditions
- Urinary Bladder, Overactive, Urinary Incontinence, Accidental Falls
- Trial name
- NCT05880862
- Testing
- Pelvic Floor Muscle Training, Mirabegron, Trospium Chloride
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Overactive Bladder
Efficacy of Electroacupuncture Versus Solifenacin Succinate for Female Overactive Bladder
Through a scientific and standardized multicenter, blinding, double-dummy, randomized controlled, noninferiority clinical trial study method, the investigators evaluated electroacupuncture as a safe and effective…
- Trial name
- NCT05798403
- Testing
- electroacupuncture, Solifenacin Succinate Tablets
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Yin Ping
Overactive Bladder, Overactive Bladder (OAB)
Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women
The goal of this clinical trial is to learn if a vaginal radiofrequency (RF) device called MORPHEUSV works to treat overactive bladder (OAB) in women. Researchers also want to learn how safe the device is for this indication.
- Conditions
- Overactive Bladder, Overactive Bladder (OAB), Urge Urinary Incontinence, Mixed Urinary Incontinence (Urge-Predominant)
- Trial name
- DENARA (NCT07209397)
- Testing
- Detrusor nerve radiofrequency ablation
- Where
- 9 sites in United States
- Volunteers
- 202 people
- Sponsor
- InMode MD Ltd.
Overactive Bladder
Efficacy and Safety of Botulinum Toxin A for the Treatment of Refractory Overactive Bladder.
Overactive bladder induce urgency, urge incontinence, nocturia and pollakiuria. This condition is often resistant to anticholinergic drugs used as a first line treatment for this purpose.
- Trial name
- NCT00231491
- Testing
- Botulinum Toxin A (Botox )
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Urinary Bladder, Overactive, Incontinence, Urge
Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A
Currently, in clinical practice there has been no standardization in the number of injections a single dose of intradetrusor onabotulinumtoxin A is administered in.
- Conditions
- Urinary Bladder, Overactive, Incontinence, Urge, Incontinence, Urinary, Urinary Urge Incontinence
- Trial name
- NCT04305743
- Testing
- OnabotulinumtoxinA 100 UNT
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of South Florida
Urinary Incontinence, Urinary Bladder, Overactive
Urodynamic Testing: Can we Improve Patient Experience?
The purpose of this study is to determine whether an intervention (pre-procedure telephone call by the investigators) will reduce anxiety in women undergoing urodynamic testing (UDT) compared to usual care.
- Conditions
- Urinary Incontinence, Urinary Bladder, Overactive, Lower Urinary Tract Symptoms
- Trial name
- NCT02742389
- Testing
- Preprocedure Telephone Call
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Boston Urogynecology Associates