Clinical trials: Over-eating
Cholestasis
Effectiveness of Multicomponent Lipid Emulsion in Preterm Infants Requiring Parenteral Nutrition
The purpose of this study is to compare the effects of a multicomponent lipid emulsion containing 30% soybean oil, 30% medium-chain triglycerides, 25% olive oil, and 15% fish oil with a conventional pure soybean oil lipid…
- Trial name
- NCT02663453
- Testing
- multicomponent lipid emulsion, pure soybean oil lipid emulsion
- Volunteers
- 44 people
- Sponsor
- Thammasat University
Prader-Willi Syndrome, Obesity
Understanding the Role of Gut Microbiota in Hyperphagia in Prader-Willi Syndrome
This study aims to use a high-fiber supplementation, an intervention known to create shifts in the gut microbiota towards a healthier structure, to explore the relationship between gut microbiota, appetite control and feeding…
- Trial name
- PWSGUT (NCT05541003)
- Testing
- NBT-NM108
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Essential Fatty Acid Deficiency (EFAD)
Pediatric Study to Evaluate Risk of Developing Essential Fatty Acid Deficiency When Receiving Clinolipid or Standard-of-Care Lipid Emulsion
This will be a descriptive study designed to evaluate the propensity for hospitalized pediatric patients treated adequately with Clinolipid or standard of care for up to 90 days to develop Essential Fatty Acid Deficiency (EFAD).
- Trial name
- NCT02476994
- Testing
- Clinolipid, Intralipid
- Where
- 4 sites in United States
- Volunteers
- 1 people
- Sponsor
- Baxter Healthcare Corporation
Essential Fatty Acid Deficiency (EFAD)
Pediatric Study to Evaluate Risk of Developing Essential Fatty Acid Deficiency When Receiving Clinolipid or Standard-of-Care Lipid Emulsion (Part A)
This will be a descriptive study designed to evaluate the propensity for hospitalized pediatric patients treated adequately with Clinolipid or standard of care (Intralipid) from 7 up to 90 days to develop Essential Fatty Acid…
- Trial name
- NCT04555044
- Testing
- Clinolipid, Intralipid
- Where
- 9 sites in United States
- Volunteers
- 101 people
- Sponsor
- Baxter Healthcare Corporation
Hyperphagia, Prader-Willi Syndrome
Pilot Study of Startle-response Test to Assess Transcranial Direct Current Stimulation-induced Modulation of Hyperphagia in Prader-Willi Syndrome
The purpose of this study is to determine the effects of transcranial direct current stimulation (tDCS) as it modifies hyperphagia in obese subjects, non-obese subjects, and subjects with Prader-Willi syndrome (PWS).
- Trial name
- NCT01863017
- Testing
- tDCS
- Where
- 3 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Self-regulation, Binge Eating
Using Mobile Technology to Better Understand and Measure Self-Regulation
This study will evaluate the extent to which we can engage and manipulate putative targets within the self-regulation domain outside of laboratory settings in samples of smokers and overweight/obese individuals with binge eating…
- Conditions
- Self-regulation, Binge Eating, Smoking
- Trial name
- NCT03352713
- Testing
- Laddr
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Alcohol; Use, Problem, Stress
A Behavioral Activation Intervention Administered in a College Freshman Orientation Course
The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use.
- Conditions
- Alcohol; Use, Problem, Stress, Binge Eating, Depression
- Trial name
- NCT04038190
- Testing
- behavioral activation
- Where
- United States
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Bulimia Nervosa, Binge Eating
Binge Eating & Birth Control
This pilot study examines the effect of stabilizing ovarian hormones on eating behaviors and brain activation in women with binge eating (n=15) using functional magnetic resonance imaging (fMRI) and behavioral tests.
- Conditions
- Bulimia Nervosa, Binge Eating, Eating Disorders, Binge-Eating Disorder
- Trial name
- NCT04278755
- Testing
- Drospirenone-Ethinyl Estradiol Oral Tablet
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of North Carolina, Chapel Hill
Parenteral Nutrition (No Primary Condition Studied)
Dosing Study of Amino Acids in Seriously Ill Patients
The purpose of this study is to determine the best rate of infusion of amino acids (15% CLINISOL - sulfite-free (Amino Acid) Injection) for nutrition in subjects with with stages II to IVB head and neck cancer.
- Trial name
- NCT01923480
- Testing
- 15% CLINISOL - Sulfite-free (Amino Acid) Injection
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Baxter Healthcare Corporation
Malnutrition, Child
Safety and Efficacy Study to Compare Smoflipid and Intralipid 20% in Pediatric Patients of 3 Months to 16 Years of Age
Evaluate the safety and efficacy of Smoflipid compared to standard of care lipid emulsion Intralipid 20% administered via a central vein in pediatric patients 3 months to 16 years of age who require parenteral nutrition for at…
- Trial name
- NCT03563222
- Testing
- Smoflipid, Intralipid, 20%
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Fresenius Kabi
Bulimia Nervosa
Neurobiology of Bulimia Nervosa
This pilot study experimentally manipulates ovarian hormones to examine the direct impact of estrogen (E2) and progesterone (P4) on binge eating symptom burden and the behavioral reward response in women with bulimia nervosa…
- Trial name
- NCT04225221
- Testing
- Estradiol, Micronized progesterone, Leuprolide Acetate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Binge Eating
Study of Behavioral Weight Loss Therapy for Obesity and Binge Eating in Monolingual Hispanic Persons
This is a research study designed to examine the effectiveness of an obesity medication (orlistat) given in addition to behavioral weight loss therapy. Participants will be obese monolingual (Spanish-speaking only) men and women.
- Trial name
- NCT00516919
- Testing
- Xenical + behavioral intervention
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Yale University
Short Bowel Syndrome
Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome
The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of teduglutide compared with placebo in subjects with parenteral nutrition (PN)-dependent short bowel syndrome (SBS).
- Trial name
- NCT00081458
- Testing
- Teduglutide 0.05 mg/kg/d, Teduglutide 0.1 mg/kg/d
- Where
- 32 sites in United States, Belgium and 7 more
- Volunteers
- 84 people
- Sponsor
- Shire
Anorexia Nervosa, Bulimia Nervosa
App-Based Mindfulness Training for Individuals With Anorexia Nervosa and Bulimia Nervosa
We will evaluate the acceptability and feasibility of a 8-week long digital mindfulness-based intervention for anorexia nervosa and bulimia nervosa.
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Anorexia Nervosa, Atypical, Bulimia; Atypical
- Trial name
- NCT05753410
- Testing
- Mindful Courage
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Yeshiva University
Impulsivity, Compulsive Overeating
tDCS for Impulsivity and Compulsivity in Obesity
Even when they know it can improve health, many individuals with loss of control eating struggle when they are trying to make and sustain new health habits for weight loss and maintenance of weight loss.
- Conditions
- Impulsivity, Compulsive Overeating, Obesity
- Trial name
- NCT04405089
- Testing
- Device: Active Transcranial Direct Current Stimulation (tDCS) coupled with cognitive training
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Bulimia Nervosa
Self-Control in Bulimia Nervosa
This study examines the influence of acute fasting and eating on self-control in adult females with and without bulimia nervosa (BN).
- Trial name
- NCT04409457
- Testing
- fasting state, fed state, magnetic resonance imaging
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Binge Eating, Depression
Study of Duloxetine vs Placebo in Treatment of Binge Eating Disorder With Depression
The purpose of this research study is to test the safety of duloxetine and see what effects (good and bad) it has on the subject's binge eating disorder and comorbid depressive disorder (depression occurring with binge eating…
- Trial name
- NCT00607789
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Cincinnati
Allogeneic Stem Cell Transplant, Graft Versus Host Disease
Nutrition and Outcomes of Hematopoietic Cell Transplantation (HCT)
Retrospective case-note review to determine if nutrition via the enteral compared to the parenteral route results in better outcomes after haematopoietic cell transplantation.
- Conditions
- Allogeneic Stem Cell Transplant, Graft Versus Host Disease, Hematologic Malignancy, Stem Cell Transplant Complications
- Trial name
- NCT03419078
- Volunteers
- 484 people
- Sponsor
- Imperial College Healthcare NHS Trust
Cholestasis, Cholestasis of Parenteral Nutrition
Omegaven as Alternative Parenteral Fat Nutrition
To provide Omegaven® as a compassionate treatment for critically ill infants with parenteral nutrition associated cholestasis
- Trial name
- NCT03662282
- Testing
- Omegaven
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of South Florida
Prematurity
The Effect of Lipid Emulsions on Free Fatty Acids and Free Bilirubin in Premature Newborns
The goal of this research study is to compare the levels of free fatty acids and free bilirubin between two intravenous lipid emulsion products in premature newborns.
- Trial name
- NCT03857646
- Testing
- Intralipid, 20% Intravenous Emulsion, Soybean oil Medium-chain triglycerides Olive oil Fish Oil (SMOF) lipid
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- The University of Texas Health Science Center, Houston