Clinical trials: Ovarian Function
Gonadotropin Releasing Hormone Agonists, Ovarian Function
Gonadotropin-Releasing Hormone Agonists Benefit in Preserving the Ovarian Function in Premenopausal Breast Cancer Patients During Chemotherapy
The purpose of this study is to investigate the benefits of gonadotropin-releasing hormone agonist administration during chemotherapy on preserving ovarian function and Fertility in Premenopausal breast cancer patients, as…
- Conditions
- Gonadotropin Releasing Hormone Agonists, Ovarian Function, Premenopausal, Breast Cancer
- Trial name
- NCT07127315
- Testing
- Gonadotropin-releasing hormone agonist, Chemotherapy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Diminished Ovarian Reserve (DOR)
Guishen Yijing Granules for Diminished Ovarian Reserve With Kidney Deficiency Syndrome: A Randomized Controlled Trial
This study is a multicenter, stratified block-randomized, double-blind, double-dummy clinical trial designed to evaluate the efficacy and safety of Guishen Yijing Granules in patients with diminished ovarian reserve (DOR) and…
- Trial name
- NCT07841548
- Testing
- Guishen Yijing Granules, Coenzyme Q10 (drug)
- Volunteers
- 120 people
- Sponsor
- Shi Yun
Infertility, Female, Perimenopausal Disorder
Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women
Autologous PRP intra ovarian infusion may improve ovarian response and women's hormonal profile and may promote folliculogenesis in perimenopausal women.
- Conditions
- Infertility, Female, Perimenopausal Disorder, Menstrual Cycle Abnormal
- Trial name
- PRP (NCT03951194)
- Testing
- Autologous Platelet Rich Plasma (PRP) intra ovarian infusion
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Cancer
A Structured Walking Program or Standard Therapy in Cancer Patients Undergoing a Donor Bone Marrow Transplant
RATIONALE: A walking program may improve the ability to carry out daily activities after donor bone marrow transplant. PURPOSE: This randomized clinical trial is studying a structured walking program to see how well it works…
- Trial name
- NCT00445731
- Testing
- exercise intervention, management of therapy complications, observation
- Volunteers
- 115 people
- Sponsor
- University of Minnesota
Ovarian Cancer, Sexual Function
Advanced Ovarian Cancer and Sexuality Phase 1
Women with Advanced Ovarian Cancer (AOC) suffer from severe sexual side effects from treatment. The prevalence of the sexual issues is not known.
- Trial name
- ANOVA1 (NCT00488202)
- Where
- 2 sites in Canada
- Volunteers
- 26 people
- Sponsor
- University of British Columbia
Female Infertility
Follow-up of Ovarian Function in Young Women Who Underwent Ovarian Cortex Cryopreservation
Evaluation of ovarian function by a questionnaire and by medical file analysis of women and girls who underwent ovarian cortex cryopreservation for fertility preservation between 1997 an 2013 in the investigators' institution in…
- Trial name
- NCT02454829
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 546 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Ovarian Function Insufficiency
Ovarian Function After Hysterectomy With or Without Fimbriectomy or Salpingectomy
The impact of Hysterectomy with preservation of the ovaries on ovarian function has long been controversial. studies have shown conflicting data regarding ovarian function after simple Hysterectomy.
- Trial name
- NCT01782807
- Testing
- Salpingectomy or Fimbriectomy
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Endometriosis Ovary, Laparoscopy
Ovarian Function After Use of Various Hemostatic Techniques During Treatment for Endometrioma
Background: Endometriosis is defined by the presence of endometrial tissue outside the uterine cavity due to causes not yet fully elucidated.
- Conditions
- Endometriosis Ovary, Laparoscopy, Ovary; Functional Disturbance, Hemostasis
- Trial name
- Endometrioma (NCT03430609)
- Testing
- Laparoscopic treatment for endometrioma Astus©, AMH Level, Transvaginal ultrasound for antral follicle count
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial
This phase II trial compares leuprolide to goserelin for reducing estrogen production by the ovaries in pre- or peri-menopausal women with breast cancer. Estrogen can cause the growth of breast cancer cells.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8
- Trial name
- NCT07158021
- Testing
- Biospecimen Collection, Electronic Health Record Review, Goserelin
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Michigan Rogel Cancer Center
IVF, Ovarian Cysts
GnRH Antagonist Pre-treatment in the Early Follicular Phase for Resolution of a Baseline Functional Ovarian Cyst
In this study we would like to examine the effect of GnRH antagonist administration at the beginning of the follicular phase in patient presenting with a simple ovarian cyst 25-50 mm.
- Trial name
- NCT04993924
- Testing
- Cetrorelix Acetate, Ganerelix Acetate
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Assaf-Harofeh Medical Center
Laparoscopic Hysterectomy
Effects of Salpingectomy During Laparoscopic Hysterectomy on Ovarian Function
The purpose of this study is to assess the feasibility of performing a randomized clinical trial evaluating the effect of salpingectomy (removal of the fallopian tubes) during laparoscopic hysterectomy on ovarian function.
- Trial name
- NCT01578759
- Testing
- Salpingectomy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Polycystic Ovary Syndrome
Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS
Polycystic ovary syndrome (PCOS) is the most common reproductive disorder in women of reproductive age and despite decades of research the etiology the disorder is not known.
- Trial name
- PULSE (NCT01482286)
- Testing
- Metformin, Dietary Restriction, Exercise Training
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Pennington Biomedical Research Center
Contraception
A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012)
The primary objective of this trial was to identify at least one next generation ring (NGR) that demonstrates inhibition of ovulation (which was considered confirmed if in the subset of participants ovulation was observed in less…
- Trial name
- NCT01709318
- Testing
- Nomegestrol acetate (NOMAC), Etonogestrel (ENG), Ethinyl estradiol (EE)
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Amenorrhea, Dysmenorrhea
Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants
This project is examining the reproductive effects of exposure to certain compounds that are suspected to act on the endocrine system, e.g. they may act like or interfere with hormones such as estrogen.
- Conditions
- Amenorrhea, Dysmenorrhea, Oligomenorrhea, Anovulation
- Trial name
- NCT00011388
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Quality of Life
Anxiety and Sexual Malfunction Functions in Infertile Pcos Women
Polycystic ovary syndrome (PCOS) is a common hormonal disorder in females in reproductive age associated with signs and symptoms as amenorrhea or oligomenorrhea, obesity,infertility acne and hirsutism tism that mostly Reduce self…
- Trial name
- NCT05056272
- Where
- Egypt
- Volunteers
- 129 people
- Sponsor
- Assiut University
Ovarian Cyst Benign
PReservation Study of Ovarian Function And Hemostasis, and Its Safety of Surgiguard@ During Laparoscopic Ovarian Cystectomy
The purpose of this study is to compare hemostasis, ovarian function preservation effect, and safety about intraoperative bleeding with SurgiGuard@ in women who underwent laparoscopic unilateral ovarian cystectomy
- Trial name
- PRAHA (NCT03374397)
- Testing
- Surgiguard
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Breast Cancer, Head and Neck Cancer
Docetaxel in Treating Patients With Solid Tumors and Abnormal Liver Function
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of docetaxel in treating patients with advanced solid…
- Conditions
- Breast Cancer, Head and Neck Cancer, Lung Cancer, Ovarian Cancer
- Trial name
- NCT00002901
- Testing
- docetaxel
- Where
- 3 sites in United States
- Sponsor
- City of Hope Medical Center
Polycystic Ovary Syndrome
Study of Brain Function in Women With Insulin Resistant Polycystic Ovary Syndrome
The purpose of this study is to evaluate the effects of insulin resistance on brain function in women with Polycystic Ovary Syndrome (PCOS).
- Trial name
- NCT00670800
- Testing
- Metformin
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Amenorrhea, Hypoaldosteronism
Ovarian Follicle Function in Patients With Primary Ovarian Failure
No proven therapy to restore ovarian function and fertility is available to patients with karyotypically normal spontaneous premature ovarian failure.
- Conditions
- Amenorrhea, Hypoaldosteronism, Hypogonadism, Infertility
- Trial name
- NCT00001275
- Where
- United States
- Volunteers
- 1,134 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Advanced Epithelial Ovarian Cancer
Comparison of Weekly Versus Every Three Weeks of Carboplatin Plus Paclitaxel in Patients With Advanced Epithelial Ovarian Cancer
The aim of the current study is to compare weekly versus three-week collective of carboplatin/paclitaxel in advanced epithelial ovarian cancer.
- Trial name
- NCT05963334
- Testing
- Carboplatin/paclitaxel
- Where
- Egypt
- Volunteers
- 49 people
- Sponsor
- Cairo University