Clinical trials: Ovarian Cyst
Polycystic Ovary Syndrome
Incretin Secretion in Women With Polycystic Ovary Syndrome (PCOS)
The incretin hormones are secreted from the gastrointestinal tract in response to nutrient ingestion, and are responsible for 70 % of insulin secretion in response to glucose.
- Trial name
- NCT00647023
- Testing
- metformin
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Controlled Ovarian Hyperstimulation, Polycystic Ovarian Syndrome
Progesterone Primed Ovarian Stimulation Versus GnRH Antagonist Protocols in Women With Polycystic Ovarian Syndrome
The purpose of this study is to compare the use of the progesterone-primed ovarian stimulation protocol versus GnRH antagonist protocol in women with polycystic ovarian syndrome (PCOS) regarding the number of oocytes retrieved…
- Trial name
- NCT06812559
- Testing
- Progesterone, GnRH antagonist (Cetrorelix)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- El Shatby University Hospital for Obstetrics and Gynecology
Polycystic Ovary Syndrome
Study of Pharmacodynamics of LIK066 in Overweight and Obese Women With Polycystic Ovary Syndrome
The purpose of the study was to evaluate whether LIK066 can be developed for the treatment of polycystic ovary syndrome (PCOS) in overweight and obese women.
- Trial name
- PCOS (NCT03152591)
- Testing
- LIK066
- Where
- 5 sites in United States, Germany
- Volunteers
- 29 people
- Sponsor
- Novartis Pharmaceuticals
Polycystic Ovarian Syndrome, Vitamin D Deficiency
Health Benefits of Vitamin D and Calcium in Women With PCOS (Polycystic Ovarian Syndrome)
The investigators conducted a prospective un-blinded pilot study of Vitamin D plus Calcium (Ca) supplementation in overweight (BMI > 27) premenopausal women diagnosed with Polycystic Ovarian Syndrome (PCOS), as defined by the…
- Trial name
- NCT00743574
- Testing
- Vitamin D2 (Ergocalciferol), Medroxyprogesterone (Provera), Vitamin D3 (Cholecalciferol)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Yale University
Polycystic Ovary Syndrome
The Role of Autoimmunity and Obesity in Polycystic Ovary Syndrome
The goal of the study is to detect autoantibodies in the serum of the women with PCOS and evaluate the obesity markers to investigate the the role of autoimmunity and obesity in PCOS
- Trial name
- NCT05929950
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Anovulation, Polycystic Ovary Syndrome
Ovarian Laser Treatment in Women With Polycystic Ovarian Syndrome: A Randomized Study on the Laser Dose
BACKGROUND: A new effective way, transvaginal ultrasound-guided ovarian interstitial laser-coagulation treatment, in management of anovulation in patients with polycystic ovary syndrome (PCOS), has been presented in the data…
- Conditions
- Anovulation, Polycystic Ovary Syndrome, Infertility
- Trial name
- NCT00643708
- Testing
- ovarian interstitial laser treatment
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Shen-Zhen City Maternity and Child Healthcare Hospital
Polycystic Ovarian Syndrome (PCOS), Reproductive Health
Management of Polycystic Ovarian Syndrome-associated Reproductive Dysfunction Through Kefir Supplementation
Polycystic ovary syndrome (PCOS) affect around 6-12% of women of age 18-25 years. Kefir contains bioactive compounds such as lactic acid bacteria, yeast, peptides, polysaccharides and organic acids and acts as a good probiotic…
- Trial name
- NCT07711782
- Testing
- (C0) Control group, (G1) Experimental group
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Lahore
Polycystic Ovary Syndrome
Safety of Hormonal Contraceptives Therapies in Polycystic Ovary Syndrome (PCOS) Women
The purpose of this study to assess early markers of cardiovascular disease in women with polycystic ovary syndrome in use of oral contraceptive containing ethynilestradiol and chlormadinone acetate alone or associated with…
- Trial name
- NCT00842140
- Testing
- oral contraceptive, Oral contraceptive plus spironolactone, Oral contraceptive plus metformin
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- University of Sao Paulo
Polycystic Ovary Syndrome (PCOS)
MLE4901 vs. Placebo for the Treatment of PCOS
This is a Phase 2b double-blind, randomized, parallel-group, placebo-controlled study of MLE4901 versus placebo in women with PCOS.
- Trial name
- NCT02865915
- Testing
- MLE4901
- Where
- 31 sites in United States
- Volunteers
- 55 people
- Sponsor
- Millendo Therapeutics US, Inc.
Female Infertility Associated With Anovulation
Amlodipine on Blood Flow of Preovulatory Follicle in Polycystic Ovarian Patients
On the basis of the current study, amlodipine seems to be a promising drug on improving uterine, ovarian blood flow, size of pre-ovulatory follicle, midluteal progesterone level and pregnancy outcome in patients with pco.
- Trial name
- NCT02544776
- Testing
- Clomifene citrate ( clomid 50 mg ), Amlodipine
- Volunteers
- 60 people
- Sponsor
- Ahmed Fathy Ali Mohamed Ghanem
Polycystic Ovary Syndrome
Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome
The polycystic ovary syndrome is the most common endocrinopathy in reproductive age women. The pathophysiology of this syndrome remains unclear, but there are evidences that a decreased in insulin sensitivity may be related in…
- Trial name
- NCT00988078
- Testing
- Metformin
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Polycystic Ovary Syndrome (PCOS) Women
Health-related Quality of Life of Women with Polycystic Ovary Syndrome At Sohag University Hospital
It is well-established that PCOS women suffer from anxiety, depression, and markedly reduced QoL ,but There has not yet been a nationally representative study to evaluate the PCOS health related Qol and factors affecting it among…
- Trial name
- NCT06832735
- Where
- Egypt
- Volunteers
- 352 people
- Sponsor
- Sohag University
Polycystic Ovary Syndrome, Menopause
Health Risks and Barriers to Management Across the PCOS Lifespan
The overall objective of the proposed pilot project is to explore health literacy and barriers to management of PCOS across the lifespan and determine whether the cardiometabolic risks of PCOS extend beyond menopause.
- Trial name
- HERBS (NCT05769426)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
PCOS (Polycystic Ovary Syndrome), Insulinemic Response
Assessment of Metabolic Changes in Response to Glcuose Intake in Women With Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome (PCOS), is a common endocrine and metabolic condition affecting women of reproductive age.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Insulinemic Response, Overweight (BMI > 25)
- Trial name
- METFLEX (NCT07687264)
- Testing
- Oral Clucose Tolerance Test (oGTT)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Polycystic Ovary Syndrome
Mediterranean Diet as Treatment for Normal Weight Women With PCOS
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of reproductive-aged women characterized by chronic anovulation, hyperandrogenism and insulin resistance.
- Trial name
- NCT02396264
- Testing
- mediterranean diet, normocaloric diet
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona
Polycystic Ovary Syndrome, Infertility
Clomiphene Citrate Plus uFSH Versus Aromatase Inhibitor Plus uFSH in Clomiphene Resistant Infertile PCOS Women
Polycystic ovarian syndrome (PCOS) is a condition characterized by infertility, infrequent periods and amenorrhea or irregular bleeding plus anovulatory infertility.
- Trial name
- NCT01793038
- Testing
- Aromatase inhibitor (litrezole) plus uFSH arm, clomiphene citrate-uFSH arm
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Mansoura Integrated Fertility Center
PCOS
Unilateral Laparoscopic Diathermy Adjusted to Ovarian Volume
The objective of our study was to compare the efficiency of the right ULOD using thermal doses adjusted to ovarian volume (60 J/cm3) with the BLOD method at constant dose and to assess treatment efficiency.
- Trial name
- NCT01833949
- Testing
- Unilateral laparoscopic drilling, Bilateral laparoscopic drilling
- Where
- Croatia
- Volunteers
- 96 people
- Sponsor
- KBC Split
PCOS
Exogenous Ketone Supplementation in Females with Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) affects 1 in 5 females of reproductive age. Commonly characterized as a disorder of infertility, PCOS is often accompanied by 3 potent cardiovascular disease (CVD) risk factors: insulin…
- Trial name
- NCT06155708
- Testing
- Ketone, Water
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McGill University
Clomiphene Citrate Resistant Polycystic Ovary Syndrome
Efficacy of Vit E in PCOS Resistant to Clomiphene Citrate
This study evaluate the addition of Vit E to clomiphene citrate in the treatment of poly cystic ovary.Half the patients will receive both Vit E and clomiphene citrate the other half will receive clomiphene citrate only.
- Trial name
- NCT03674385
- Testing
- vitamin E, Metformin, Clomiphene Citrate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
Sub-therapeutic GnRH- Antagonist Treatment to Rectify LH Pulsatility in Lean Women With PCOS.
The clinical study using a sub-therapeutic dose of a GnRH antagonist to reduce overactive LH pulsatility in women with PCOS. With the intervention and lowered LH action we anticipate to decrease androgen levels in women with…
- Trial name
- SOPKGANI (NCT05751252)
- Testing
- Ganirelix
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Lille
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