Clinical trials: Outcome Assessment
Syncope
Evaluation of Syncope,Its Diagnosis, Treatment, Outcome and Prognosis
The investigators want to look at how patients admitted after passing out (syncope) or nearly passing out (pre-syncope) do after going home and how many of them remain free of symptoms of syncope or pre-syncope.
- Trial name
- E-STOP (NCT00764985)
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Moderate to Severe Plaque Psoriasis
An Observational Study to Evaluate Patient-Reported Experiences of Living With Moderate-to-Severe Plaque Psoriasis
The purpose of the study is to develop a database containing patient-reported information that may be used to understand and to increase awareness of the impact that moderate-to-severe plaque psoriasis can have on both daily life…
- Trial name
- NCT01555606
- Testing
- No intervention
- Where
- 9 sites in United States
- Volunteers
- 108 people
- Sponsor
- Janssen Biotech, Inc.
Amyotrophic Lateral Sclerosis, Motor Neurone Disease
Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project
Amyotrophic Lateral Sclerosis (ALS), the most common form of Motor Neuron Disease (MND), is a neurodegenerative disease. At present there are limited treatment options for this disease which progressively affects physical…
- Trial name
- TechnicALS (NCT06820008)
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- University of Dublin, Trinity College
Placenta Praevia, Vaginismus
Transperineal Ultrasound to Assess the Progress of Labour
This is a prospective observational study of transperineal ultrasound between 24-42 weeks gestation and a prospective longitudinal observational study in all term (37-42 weeks) labouring women.
- Trial name
- NCT02430038
- Where
- United Kingdom
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Apico Marginal Defects
Comparative Evaluation of Two PRF Formulations on Quality of Life and Healing of Apicomarginal Defects
Healing of apicomarginal defects using 2 different formulations of PRF i.e PRF -high and PRF-medium will be assessed and compared using 2D and 3D criteria.
- Trial name
- NCT04396743
- Testing
- Periapical surgery with use of prf-high clot and membrane, Periapical surgery with use of prf-medium clot and membrane
- Where
- India
- Volunteers
- 32 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Substance Use Disorders, HIV
Achieving Equity in Patient Outcome Reporting for Timely Assessments of Life With HIV and Substance Use
This study aims to achieve health equity in substance use disorder (SUD) screening and treatment among people living with human immunodeficiency virus (HIV) by implementing interventions to decrease barriers to screening…
- Trial name
- ePORTAL-HIV-S (NCT06682468)
- Testing
- Population level patient portal based substance involvement screening, Usual Care Substance Use Involvement Screening
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- University of Chicago
Obesity, Pregnancy
Effect of Physical Activity on Metabolic Syndrome in Pregnancy & Fetal Outcome
The purpose of this study is to examine the effect of exercise during pregnancy upon maternal metabolism, including weight gain, fat distribution, and levels of glucose and cholesterol.
- Conditions
- Obesity, Pregnancy, Diabetes Mellitus
- Trial name
- NCT00647595
- Testing
- Experimental group
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Burns, Liver Fibroses
Liver, Pancreas and Thyroid Function in Burn Patients
The purpose of this study is to determine the extent to which severe burn injuries affect the morphology and function of liver, pancreas and thyroid.
- Conditions
- Burns, Liver Fibroses, Pancreas Disease, Thyroid Diseases
- Trial name
- NCT03598283
- Testing
- Ultrasound/transient elastography
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
HIV Infection, Tuberculosis
Immunosuppression in HIV-infected Patients With Tuberculosis in Ethiopia
Background: Tuberculosis (TB) and HIV are leading causes of disease and death in Subsaharan Africa. Antiretroviral therapy (ART) dramatically improves prognosis in HIV infection, but TB is still a common complication in…
- Conditions
- HIV Infection, Tuberculosis, Immunosuppression
- Trial name
- NCT01252537
- Where
- 5 sites in Ethiopia
- Volunteers
- 1,200 people
- Sponsor
- Lund University
Osteoarthritis
Roentgen Stereophotogrammetric Analysis (RSA) Trial Comparing Trabecular Metal Monoblock and Modular Tibial Components
Total knee replacement is an effective option for treating chronic knee conditions that cause pain and functional impairment. Significant improvements in quality of life, as measured by both disease specific and generic quality…
- Trial name
- NCT01180595
- Testing
- Trabecular Metal Modular Tibial Total Knee Component, Trabecular Metal Monoblock Tibial Total Knee Component
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Dalhousie University
AML
Registry of Patients Having Received oNKord®
ReKORD is an observational study (Registry) enrolling participants who have received at least one dose of oNKord® (allogeneic ex vivo-generated Natural Killer [NK] cells from CD34+ umbilical cord blood progenitor cells) in a…
- Trial name
- NCT05290662
- Testing
- oNKord®, Cyclophosphamide/Fludarabine (Cy/Flu)
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 50 people
- Sponsor
- Glycostem Therapeutics BV
Inguinal Hernia
Dynamic Scaffold Versus Lichtenstein Open Hernioplasty.
Evaluating the outcomes of patients undergoing open anterior inguinal hernioplasty comparing two different techniques: Lichtenstein/plug and mesh and ProFlor.
- Trial name
- DYSLOH (NCT05706662)
- Testing
- inguinal hernia repair with mesh
- Where
- Italy
- Volunteers
- 188 people
- Sponsor
- University of Palermo
Erectile Dysfunction, Spinal Cord Injuries
Efficacy and Safety of Tadalafil in Subjects With Erectile Dysfunction Caused by Spinal Cord Injury
This is a study of the efficacy and safety of on-demand dosing of tadalafil or placebo administered for 12 weeks to men with erectile dysfunction caused by spinal cord injury.
- Trial name
- NCT00421083
- Testing
- tadalafil
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Eli Lilly and Company
Opioid-use Disorder, Opioid-related Disorders
An Observational Study of Environmental and SocioEconomic Factors in Opioid Recovery
The RECOVER Study will examine clinical, environmental and socioeconomic factors in recovery from opioid use disorder (OUD) over a 24-month period following exit from a Phase III clinical program for a buprenorphine…
- Trial name
- RECOVER® (NCT03604861)
- Testing
- Not applicable - no defined intervention
- Where
- 35 sites in United States
- Volunteers
- 534 people
- Sponsor
- Indivior Inc.
Surgery
Natriuretic Peptides - Predictors of In-hospital and Long-term Major Adverse Cardiac Events After Emergency Surgery?
The investigators hypothesize that the level of perioperative natriuretic peptides is associated with in-hospital and long term major adverse cardiac events.
- Trial name
- NCT00942786
- Where
- Austria
- Volunteers
- 297 people
- Sponsor
- Medical University of Graz
Osteoarthritis, Knee
Assessment With Gait Analysis of Robotic Total Knee Arthroplasty Using Inverse Kinematic Alignment
Postoperative function and patient satisfaction are becoming increasingly relevant in patients after knee arthroplasty surgery. Despite adequate preoperative planning, improved surgical techniques and rehabilitation protocols…
- Trial name
- RATKA-CBO (NCT04912973)
- Testing
- Robotically Assisted Total Knee Arthroplasty - Knee Replacement
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Philip Winnock de Grave, MD
Spinal Neoplasms
Evaluation of Effectiveness of CyberKnife Stereotactic Radiosurgery for Spinal Tumors
This study aims to explore the reliability of the combination of functional magnetic resonance imaging and radiomics for evaluation of the therapeutic efficacy of CyberKnife stereotactic radiosurgery for spinal tumors.
- Trial name
- NCT04192383
- Testing
- Cyberknife stereotactic radiosurgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Charcot-Marie-Tooth Disease Type 1A
Tools for Therapeutic Evaluation in Charcot-Marie-Tooth Disease Type 1A: Outcome Measures and Biomarkers
This is a 2-year follow-up study of a cohort of 60 CMT1A patients. The objective is to identify markers allowing to better understand the phenotypic variability observed on patients with CMT1A, to identify predictive markers of…
- Trial name
- CMT-TOOLS (NCT02596191)
- Testing
- Clinical evaluation, electrophysiological record, Muscle MRI
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Ewing Sarcoma, Osteosarcoma
Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young Adults
The purpose of the study was to investigate whether functional MRI imaging (diffusion weighted imaging) is useful for monitoring the therapeutic response of bone sarcomas in children and young adults.
- Trial name
- FUBEO (NCT01780779)
- Testing
- MRI
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Coronavirus Infections, Diabetes Mellitus
Covid-19 and Diabetes in West of Algeria
By Jan 7, 2020, Chinese scientists had isolated a novel coronavirus, from patients with virus-infected pneumonia. The WHO designated later this virus as COVID-19 (coronavirus disease 2019).
- Conditions
- Coronavirus Infections, Diabetes Mellitus, Prevalence, Risk Factors
- Trial name
- COVIDIAB-13 (NCT04412746)
- Testing
- MANAGEMENT OF COVID-19
- Where
- Algeria
- Volunteers
- 100 people
- Sponsor
- Laboratoire De Recherche Sur Le Diabete, Université de Tlemcen