Clinical trials: Outcome, Fatal
Traumatic Brain Injury, Fluid Overload
Neutral Versus Liberal fLuId In Traumatic Brain Injury: a Randomised Controlled Trial
Feasibility and safety of targeting neutral vs liberal fluid balance in traumatic brain injured patients: a phase II randomized controlled trial
- Conditions
- Traumatic Brain Injury, Fluid Overload, Outcome, Fatal
- Trial name
- LIMIT (NCT05983549)
- Testing
- fluid balance
- Volunteers
- 80 people
- Sponsor
- Universita degli Studi di Genova
Dyspnea, Emergencies
European Dyspnoea Survey in the EMergency Departments
Braunwald defines dyspnoea as an abnormally uncomfortable awareness of breathing. Breathing discomfort, and its varying degrees of severity, is the one of the most disturbing symptoms patients can experience; and it is one of the…
- Trial name
- EuroDEM (NCT02060799)
- Where
- 10 sites in Belgium, Finland and 8 more
- Volunteers
- 2,156 people
- Sponsor
- Hopital Lariboisière
Cause of Mortality, Cause of Neonatal Death
Defining Causes of Deaths in South and Southeast Asia
Brief Summary: Mortality data are important in low and middle-income countries to assess the population health status and trends.
- Conditions
- Cause of Mortality, Cause of Neonatal Death, Cause of Child Death, Cause of Maternal Death
- Trial name
- SEACTN-VA (NCT04595656)
- Testing
- verbal autopsy interview
- Where
- 5 sites in Bangladesh, Burma and 3 more
- Volunteers
- 3,413 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Outcome, Fatal, Spondylodiscitis
Spine Registry University Hospital of Cologne- Department of Orthopedics
Between January 2008 and December 2020 all patients with spine diseases were registered prospectively in the former European Spine Tango registry and later german DWG registry at the department of orthopedics and trauma at the…
- Conditions
- Outcome, Fatal, Spondylodiscitis, Vertebral Osteomyelitis
- Trial name
- NCT05486494
- Testing
- Treatment (non- surgical/surgical)
- Volunteers
- 355 people
- Sponsor
- University of Cologne
Fatal Outcome
Physician Versus Computer Coding of Verbal Autopsies
The objective of this study is to compare the performance of computer-coded verbal autopsies (CCVA) to physician-coded verbal autopsies (PCVA) at the population level.
- Trial name
- NCT02810366
- Testing
- Physician versus Computer Coded Verbal Autopsy
- Where
- 3 sites in India
- Volunteers
- 12,500 people, healthy volunteers welcome
- Sponsor
- Centre for Global Health Research, Toronto
Septic Shock, Multiple Organ Failure
Severe Sepsis/Septic Shock on Admission to the General Surgical ICU
Severe sepsis/septic shock are serious complications of infection with high morbidity and mortality. Recent information showed that early and aggressive resuscitation may help improving survival and outcome especially the…
- Conditions
- Septic Shock, Multiple Organ Failure, Fatal Outcome
- Trial name
- NCT01363635
- Where
- Thailand
- Volunteers
- 800 people
- Sponsor
- Mahidol University
Acute Kidney Injury, Outcome, Fatal
Effect of Weekend Admission on Mortality Associated With Severe Acute Kidney Injury in England: a Propensity Score Matched, Population-based Study
Increased in-hospital mortality associated with weekend admission has been reported for many acute conditions, but no study has investigated "weekend effect" for acute kidney injury requiring dialysis (AKI-D).
- Trial name
- NCT02947698
- Volunteers
- 53,878 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Heart Arrest, Cardiac Arrest
Resuscitation Outcomes in the Netherlands
The Resuscitation Outcomes in the Netherlands - study assesses one-year survival and quality of life after In-Hospital Cardiac Arrest(IHCA).
- Conditions
- Heart Arrest, Cardiac Arrest, Cardiac Arrest as A Complication of Care, Outcome, Fatal
- Trial name
- ROUTiNE (NCT03120507)
- Where
- 12 sites in Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Sepsis, Coagulopathy
The Early Coagulopathy for the Prognosis in Sepsis
In this cohort study, the parameters (TM, TAT, PIC, tPAIC, et al.) associated with the hemostatic system will be collected in sepsis patients when admitted to the Intensive Critical Unit.
- Conditions
- Sepsis, Coagulopathy, Outcome, Fatal
- Trial name
- NCT04582188
- Volunteers
- 200 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Covid19, Outcome, Fatal
International Study of Inflammation in COVID-19
This is a prospective multi-center observational study which purpose is to evaluate the ability of blood-based inflammatory markers to risk-stratify patients hospitalized for Covid-19.
- Conditions
- Covid19, Outcome, Fatal, Respiratory Failure, Acute Kidney Injury
- Trial name
- ISIC (NCT04818866)
- Testing
- SuPAR, C-reactive protein, Ferritin, D-Dimer, Procalcitonin, Interleukin-6, Lactate Dehydrogenase
- Where
- United States
- Volunteers
- 4,463 people
- Sponsor
- University of Michigan
Adverse Drug Reaction
Adverse Drug Reactions With Fatal Outcome
The purpose of this study is to determine the incidence of drug-related deaths in a university hospital during the year 2015
- Trial name
- NCT02838212
- Testing
- adverse drug reaction
- Volunteers
- 1,135 people
- Sponsor
- Germans Trias i Pujol Hospital
COVID-19, Outcome, Fatal
Critically Ill ICU Patients Under Casirivimab- and/or Tocilizumab Application
In a retrospective observational study, critically ill COVID-19 patients admitted to the ICU with the CoV-2 delta-variant between august 2021 and february 2022 were evaluated (ethics application nr.
- Conditions
- COVID-19, Outcome, Fatal, Tocilizumab, Interleukin 6
- Trial name
- CasiTocCOVID (NCT06233357)
- Testing
- treated without (N), with casirivimab / imdevimab (C) or tocilizumab (T), solely, or in combination of both (C + T)
- Where
- Germany
- Volunteers
- 95 people
- Sponsor
- University of Ulm
Apatinib, Outcome, Fatal
Apatinib for Resectable Colorectal Cancer
Objective: To compare the outcome of patients with colorectal cancer who treated with adjuvant therapy or Apatinib with adjuvant therapy postoperatively. Language: English.
- Conditions
- Apatinib, Outcome, Fatal, Colorectal Cancer, Surgery
- Trial name
- NCT03228043
- Testing
- Apatinib, CAPEOX
- Where
- China
- Sponsor
- Nanchong Central Hospital
COVID-19, Critical Illness
Analysis of Mortality of Critically Ill Patients With COVID-19
The recent pandemic of the COVID-19 disease has caused a national health emergency due to its severity and the clinical and social consequences of the disease. Crude mortality in Spain is 9.2%.
- Conditions
- COVID-19, Critical Illness, Effectiveness, Outcome, Fatal
- Trial name
- NCT04379258
- Where
- Spain
- Volunteers
- 868 people
- Sponsor
- Hospital Universitario Getafe
Outcome, Fatal
CMR Features in Patients With Suspected Myocarditis
Presentation of myocarditis is heterogeneous, often ranges from being asymptomatic, to chest pain, dyspnoea, palpitations, and even sudden cardiac death.
- Trial name
- CMRMyo (NCT03470571)
- Testing
- CMR
- Where
- United States
- Volunteers
- 670 people
- Sponsor
- Brigham and Women's Hospital
Infection Due to Resistant Bacteria, Multi-antibiotic Resistance
Resistant Bacteria in Children in France
This study is observational, multicenter and prospective study for surveillance of the use of new antibiotics in pediatrics for treated pediatrics infections due to multi-resistant bacteria
- Conditions
- Infection Due to Resistant Bacteria, Multi-antibiotic Resistance, Antibiotic Prescription, Risk Factors
- Trial name
- BREF (NCT06036628)
- Where
- France
- Volunteers
- 306 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Covid19, Kidney Transplant Infection
Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience From the Middle East
Methods: Out of 2000 kidney transplant recipients in our center in Kuwait, collecting data was started for all COVID-19-positive kidney transplant recipients till August 2020.
- Conditions
- Covid19, Kidney Transplant Infection, Risk Factor, Cardiovascular, Immunosuppression
- Trial name
- OMC-KTR (NCT04542954)
- Testing
- Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience from the Middle East
- Where
- Kuwait
- Volunteers
- 104 people
- Sponsor
- Hamid Al-Essa Organ Transplant Center
Outcome, Fatal
The HIV Testing Trends and Outcomes at a Johannesburg Trauma ICU Unit
A retrospective observational study on the HIV testing trend and outcomes in a trauma population admitted to a critical care unit for care.
- Trial name
- NCT05484947
- Testing
- Elisa HIV testing
- Where
- South Africa
- Volunteers
- 868 people
- Sponsor
- University of Witwatersrand, South Africa
Diabetes (DM), Cardio Vascular Disease
Nut Consumption and Prevention of Non-communicable Diseases: A Global Individual Participant Data Meta-analysis
The relationship between nut consumption and the risk of developing non-communicable diseases (NCDs) has been a subject of growing interest.
- Conditions
- Diabetes (DM), Cardio Vascular Disease, Cancer, Dementia
- Trial name
- NUTPOOL (NCT07205978)
- Where
- 2 sites in Denmark, Spain
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Critical Care, Medication
Stopping Cardiovascular Treatments and Mortality in a MICU
Cardiovascular treatments should not be interrupted following hospital admission, in order to decrease patients' morbidity. However, following ICU admission, such treatments are frequently interrupted and/or modified.
- Conditions
- Critical Care, Medication, Cardiovascular Diseases, Outcome, Fatal
- Trial name
- TRAM (NCT04121429)
- Testing
- Observation
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest