Clinical trials: Out-Of-Hospital Cardiac Arrest
Out-Of-Hospital Cardiac Arrest
International Termination of Resuscitation Practices
Neither the international nor the interregional variation in survival following OHCA is fully understood, but may rely on multiple factors such as: organization of the Emergency Medical Service (EMS) system bystander…
- Trial name
- NCT05029180
- Testing
- Termination of resuscitation
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Out-Of-Hospital Cardiac Arrest, Mobile Phone Use
Impact of Mobile Phone Application Use on Adult BLS
The aim of the study is to investigate whether a serious smartphone game (called MOBI-CPR game) used in the home environment has an impact on the retention of adult basic life support knowledge and skills.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Mobile Phone Use, Stress, Knowledge, Attitudes, Practice
- Trial name
- MOBI-CPR (NCT05784675)
- Testing
- MOBI-CPR game
- Where
- Slovenia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nino Fijačko
Out-Of-Hospital Cardiac Arrest
Enhanced Community First Responder System Evaluation in Singapore
The rise in out-of-hospital cardiac arrest (OHCA) cases in Singapore highlights the need for effective bystander cardiopulmonary resuscitation (BCPR).
- Trial name
- TCPR-Link (NCT06530433)
- Testing
- CPRCard + TCPR Link App and Web, CPRCard Only
- Where
- Singapore
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Cardiac Arrest, Cardiopulmonary Arrest
Use of a Feedback Device to Limit Too Shallow Compressions Associated With the Use of an I-gel® Device
Airway management in out-of-hospital cardiac arrest is still debated. Several options exist: bag-valve-mask ventilation, supraglottic devices and endotracheal intubation.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Resuscitation, Emergency Medicine
- Trial name
- NCT05709613
- Testing
- Use of a chest compressions' feedback device
- Where
- 4 sites in Switzerland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Resuscitation, Outcome, Fatal
Outcome After Out of Hospital Cardiac Arrest in Bern, Switzerland
Sudden cardiac arrests is one of the most frequent causes of death. In Switzerland every year 8000-10.000 people suffer from a cardiac arrest.
- Conditions
- Resuscitation, Outcome, Fatal, Out-Of-Hospital Cardiac Arrest
- Trial name
- NCT03759210
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Out-Of-Hospital Cardiac Arrest, Healthy
Dose-Finding Study of Intranasal Insulin in Healthy Participants Insulin in Healthy Participants
This study is to determine the safety and tolerability of regular insulin (Humulin R) when given intranasally (as drops in nostrils).
- Trial name
- NCT05062785
- Testing
- Intranasal insulin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Robert Silbergleit
Cardio Respiratory Arrest, Cardiac Death
Ventilation in Cardiac Arrest
Over the last decades, research in cardiopulmonary resuscitation was primarily focused on uninterrupted chest compressions to restore sufficient circulation.
- Conditions
- Cardio Respiratory Arrest, Cardiac Death, Ventilation Therapy; Complications, Apnea
- Trial name
- VICA (NCT04657393)
- Testing
- mechanical ventilation
- Where
- Austria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Neurological Outcome, Cardiac Arrest
Out-of-hospital Cardiac Arrest (OHCA) Biomarkers
Few early prognostic indicators are currently available for patients' families and clinicians following out of hospital cardiac arrest (OHCA), and blood biomarkers may be of prognostic value in these cases.
- Conditions
- Neurological Outcome, Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Brain Anoxia Ischemia
- Trial name
- NCT03112486
- Testing
- blood draw
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Florida
BLS, Out-Of-Hospital Cardiac Arrest
Geographical Association Between Basic Life Support Courses, Bystander Cardiopulmonary Resuscitation and Survival
Background Since 2001 when the Danish Cardiac Arrest Registry was first established several large-scale interventions aimed at the entire Danish population from all ages have been initiated.
- Trial name
- Geodata-BLS (NCT04353089)
- Testing
- Basic life support courses
- Where
- Denmark
- Volunteers
- 900,000 people, healthy volunteers welcome
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Bystander, Chest Compression
REsuscitation Survey of Police Officers in New Taipei City for Duty
Out-of-hospital cardiac arrest (OHCA) remains a time-critical emergency where early cardiopulmonary resuscitation (CPR) and timely defibrillation using an automated external defibrillator (AED) are key to improving survival and…
- Conditions
- Bystander, Chest Compression, Out of Hospital Cardiac Arrest, AED
- Trial name
- RESPOND (NCT06955351)
- Testing
- Survey by Questionnaire
- Where
- Taiwan
- Volunteers
- 4,867 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Out-Of-Hospital Cardiac Arrest
The Development of the Simulation Curriculum and AI-incorporated Assessment Tool for Transesophageal Echocardiography
This study aims to establish a novel transesophageal echocardiography (TEE) simulation curriculum based on previous research results and suggestions from the American College of Emergency Physicians.
- Trial name
- NCT06567912
- Testing
- TEE simulation curriculum
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cardiac Arrest, Out-Of-Hospital
Gathering Evidence on Best Practices for Lay Rescuer CPR Training
The goal of this prospective trial is to compare CPR skill and attitudes in lay rescuers. The main question[s] it aims to answer are: What is the optimal training timing, duration, and frequency for lay rescuers that leads to CPR…
- Trial name
- NCT05908500
- Testing
- CPR Training, CPR Manikin Type
- Where
- United States
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Cardiopulmonary Resuscitation, Education
Efficacy of Online Real-time CPR Training
The purpose of this study is to evaluate the effectiveness of a new online real-time quality measurement and feedback video-based CPR training program.
- Trial name
- NCT04656405
- Testing
- Online real-time quality measurement and feedback video-based CPR training, Online real-time feedback video-based CPR training without quality measurement, Conventional CPR training
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Out-of-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation
Improving Bystander CPR Quality Through Dispatcher-assisted Basic Life Support Education Program
In an attempt to enhance OHCA survival by increasing bystander CPR rate, this study will assess the effectiveness of the new basic life support with dispatch assistance (DA-BLS) education program through a simulation experiment.
- Trial name
- NCT02527473
- Testing
- Dispatcher-Assisted Basic Life Support CPR Education
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cardiac Arrest
Anti-inflammatory Effect of Therapeutic Hypothermia in Out-hospital Cardiac Arrest Patients With Cardiogenic Shock
Acute myocardial infarction complicated with cardiogenic shock trigger IL-6, the strong inflammatory response, result in multiple organ failure, even death.
- Trial name
- NCT02633358
- Testing
- Therapeutic hypothermia group
- Where
- Taiwan
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Pediatric ALL, Cardiac Arrest
Effect of IAM With an I-gel® on Ventilation Parameters in Simulated Pediatric OHCA
Pediatric cardiac arrest occurs most in the prehospital setting. Most of them are due to respiratory failure (e.g., trauma, drowning, respiratory distress), where hypoxia leads to cardiac arrest.
- Conditions
- Pediatric ALL, Cardiac Arrest, Cardiopulmonary Arrest, Resuscitation
- Trial name
- NCT05498402
- Testing
- i-gel ® device, bag-valve-mask ventilation
- Where
- 4 sites in Switzerland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Mental Health, Stress Disorder, Post Traumatic
Psychological Stress and Support Needs of Volunteer First Responders After Smartphone-based Cardiac Arrest Alerts
Out-of-hospital cardiac arrest is a serious emergency. In many areas, trained volunteers are alerted by a smartphone app to help before emergency services arrive.
- Trial name
- BRAVE (NCT07607808)
- Testing
- Structured Debriefing
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aachen
Coping Skills
CPR Training in Students to Increase Bystander Intervention in Out-of-hospital Cardiac Arrest.
The overall aim of this thesis is to identify the factors that may affect 13 year old students' acquisition of CPR skills and their willingness to act.
- Trial name
- NCT03233490
- Testing
- web course, CPR training
- Volunteers
- 1,547 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Out-of-hospital Cardiac Arrest (OHCA), Agonal Breathing
CPR and Agonal Breathing Recognition Training for Police Officers
This study will evaluate an educational training program for police officers in New Taipei City, Taiwan. Police officers may arrive at out-of-hospital cardiac arrest events before emergency medical services and may be able to…
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), Agonal Breathing, Cardiopulmonary Resuscitation Training
- Trial name
- CPR-AB Police (NCT07695766)
- Testing
- CPR Refresher and Agonal Breathing Recognition Training
- Where
- Taiwan
- Volunteers
- 3,439 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Sudden Cardiac Arrest
Sodium Bicarbonate in Cardiopulmonary Resuscitation
Out-of-hospital cardiac arrests (OHCA) account for over 60% of deaths from coronary artery disease. The annual incidence of OHCA treated by Emergency Medical Systems (EMS) is 41-89 per 100,000 population.
- Trial name
- SB CAT (NCT01377337)
- Testing
- sodium bicarbonate
- Where
- 2 sites in Israel
- Volunteers
- 2,130 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus