Clinical trials: Other
Psychosis, Schizophrenia
STEP-ED: Reducing Duration of Untreated Psychosis and Its Impact in the U.S.
The guiding questions for this study are: can a U.S. adaptation of a successful Scandinavian approach (TIPS) to early detection substantially reduce the duration of untreated psychosis (DUP) and improve outcomes beyond an…
- Trial name
- NCT02069925
- Testing
- Early Detection (ED), Usual Detection
- Where
- 2 sites in United States
- Volunteers
- 285 people
- Sponsor
- Yale University
Relapsing-Remitting Multiple Sclerosis, Multiple Sclerosis
An Efficacy and Safety Study of BG00012 (Dimethyl Fumarate) in Asian Subjects With Relapsing Remitting Multiple Sclerosis (RRMS)
This is a multicenter study conducted in 2 parts: The primary objective in Part I of this study is to determine the efficacy of BG00012 (dimethyl fumarate, DMF) on inflammatory brain magnetic resonance imaging (MRI) lesion…
- Trial name
- NCT01838668
- Testing
- dimethyl fumarate
- Where
- 54 sites in Czechia, Japan and 3 more
- Volunteers
- 225 people
- Sponsor
- Biogen
Frailty
Feasibility of a Multidisciplinary Student-Led Program to Improve Frailty in Nursing Home Residents
BACKGROUND Frailty, regarded as a potentially reversible process and defined as a progressive deterioration of physiological systems and intrinsic capacity, constitutes a key risk factor for disability, dependency and…
- Trial name
- CUIDAFRAIL (NCT07182747)
- Testing
- Nursing students' intervention programme, Standard care from Public Andalusian Health Service
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Almeria
Schizophrenia
Mental Health During the Whole Life Cycle of Community Patients With Schizophrenia
Schizophrenia is one of the components of severe mental disorders. It has the characteristics of prolonged course, low cure rate, high recurrence rate and high disability rate.
- Trial name
- NCT05159349
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Mental Health Center
Schizophrenia Spectrum Disorders, Schizophrenia
Safety and Efficacy of Virtual Reality Mindfulness in Patients With Psychosis
This study is to evaluate the safety and efficacy of Virtual Reality Mindfulness in Patients With Psychosis.
- Conditions
- Schizophrenia Spectrum Disorders, Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorders
- Trial name
- NCT05784948
- Testing
- Virtual Reality Mindfulness Treatment, Experience relaxing scenery and music
- Where
- South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Nutrition Disorders
PALS for Nutrition Education
The overall goal of this inquiry is to determine whether PALS is more effective than comparable online resources at educating patients in the outpatient clinic setting about nutrition.
- Trial name
- NCT04196517
- Testing
- Educational Tool, PALS, WebMD
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cow Milk Allergy
A Growth and Hypoallergenicity Study of a New Formula for Infants With Cow Milk Allergy
This study involves the use of 2 different Neocate formulas: a control formula called Neocate Infant and a test Neocate formula.
- Trial name
- CMA (NCT00664768)
- Testing
- Neocate Infant, new Neocate
- Where
- 22 sites in United States
- Volunteers
- 126 people
- Sponsor
- Nutricia North America
Substance Use Disorder
Neuromodulation in Substance Use Disorders
The primary objective of this study is to assess the safety and feasibility of FUS neuromodulation in participants with OUD and/or other SUDs.
- Trial name
- NCT07010016
- Testing
- NaviFus Model101
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Manish Ranjan
Patients With Schizophrenia, Relatives
Influence of Environmental Factors and Schizophrenia
Schizophrenia is a chronic and severe mental disorder with a lifetime prevalence of about 1 per cent, the symptoms can be very disabling and causing a heavy medical and socioeconomic.
- Trial name
- Envschi (NCT03296384)
- Testing
- Clinical and environmental evaluation
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
SCHIZOPHRENIA 1 (Disorder), Schizoaffective Disorder
Cognitive Rehabilitation With Immersive Virtual Reality (IVR) in Schizophrenia: a Pilot Randomized Waiting List Controlled Feasibility Study
Virtual reality-based rehabilitation has recently gained increasing attention in the field of cognitive rehabilitation, allowing patients to engage in simulated real-life scenarios within a safe and controlled setting.
- Trial name
- IVR SCZ (NCT07427485)
- Testing
- CEREBRUM VR, Waiting List
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Sanitaria Locale Napoli 3 Sud, UOCSM Torre del Greco
Psychosis
The Relationship Between Autobiographical Memory and Motivation
People with a diagnosis of psychosis often experience low motivation and pleasure when thinking about doing future activities. This leads, quite understandably, to doing fewer activities they used to enjoy and not taking up…
- Trial name
- NCT03677635
- Testing
- Guided Autobiographical Memory Recall
- Where
- 2 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- King's College London
Other Disorders of Bone Development and Growth
Assessing the Impact of Contraceptives on Bone Health Using 41Ca
This preclinical randomized crossover study will examine the effects of oral versus non-oral contraceptive therapy on bone turnover in young exercising women.
- Trial name
- NCT02367846
- Testing
- Combined Oral Contraceptive (COC), Contraceptive Vaginal Ring (CVR)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Penn State University
Schizophrenia
The New Strategy for Pharmacological Treatment in People With Schizophrenia
Switching from Risperidone to Aripiprazole in early stage of pharmacotherapy will demonstrate the same efficacy as compared to risperidone continuation treatment in the treatment of schizophrenia.
- Trial name
- NCT00352339
- Testing
- Rispridoen and Aripiprazole, Risperidne, Abilify
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Inje University
Schizophrenia
Clozapine Versus Chlorpromazine for Treatment-Unresponsive Schizophrenia
This study will examine the physical response to clozapine or chlorpromazine in people with schizophrenia that has not improved with treatment.
- Trial name
- NCT00169039
- Testing
- Clozapine, Chlorpromazine
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Schizophrenia
Exploratory Study of a Digital Therapeutics in People With Schizophrenia
CT-155 is a novel prescription digital therapeutic (PDT) being developed by Click Therapeutics, Inc. (Click) and Boehringer Ingelheim (BI) using an interactive, software-based intervention to treat schizophrenia
- Trial name
- NCT05438160
- Testing
- Clinical Learning Study smartphone app (i.e., the study app)
- Where
- 7 sites in United States
- Volunteers
- 48 people
- Sponsor
- Click Therapeutics, Inc.
Postpartum Period, Psychosis
Risk Factors for Postpartum Psychosis
A range of psychological disorders occur in women in the postpartum period. These include "the blues", which occurs in the first days after birth and which is very common and self-limiting; severe psychoses often associated with…
- Trial name
- RIFPP (NCT00872313)
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Nanjing Medical University
Obesity
Fit Moms in Partners, Children, and Other Members
The purpose of this ancillary study is to determine whether a behavioral weight loss intervention for postpartum mothers (5R01DK087889-02, PI Phelan; Co-I Tate) has a positive "ripple" effect on weight and health of partners and…
- Trial name
- NCT01921959
- Testing
- Intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Breast Cancer, Metastatic Breast Cancer
Phase II Study for Solid Metastatic Tumors
1. To induce immunity-mediated tumor response outside the radiation field (abscopal effect) after chemo-radiation of a metastatic site in metastatic breast cancer patients. 2. To monitor the induction of a T cell response. 3.
- Conditions
- Breast Cancer, Metastatic Breast Cancer, Solid Tumor
- Trial name
- NCT02474186
- Testing
- Radiation therapy, Xeloda, paclitaxel
- Volunteers
- 41 people
- Sponsor
- NYU Langone Health
Healthy
Single-center Study Evaluating the Safety and Efficacy of Viscogel® as Adjuvant in Act-HIB® Vaccine
The purpose of this study is to show that ViscoGel® is safe when administrated alone and as an adjuvant together with Act-HIB® vaccine in healthy volunteers and to evaluate the quantitative and qualitative effect on the immune…
- Trial name
- VSG-2011-101 (NCT01578070)
- Testing
- 0.2μg Act-HIB®, ViscoGel® and 0.2μg Act-HIB®, ViscoGel® and 2μg Act-HIB®
- Where
- Sweden
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Viscogel AB
Schizophrenia
Study Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Male and Female Subjects With Schizophrenia
This is a study designed to evaluate the safety, tolerability, and PK of SEP-363856 and its metabolite SEP-363854 in male and female subjects with schizophrenia.
- Trial name
- SEP-363856 (NCT01994473)
- Testing
- SEP-363856, SEP-363856 Open Label
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.