Clinical trials: Osteoarthritis Hand, open to volunteers
Osteoarthritis Hand, Osteoarthritis Wrist
Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis
The purpose of this research is to compare low-dose radiotherapy to corticosteroid injection for treatment of hand/wrist osteoarthritis.
- Trial name
- NCT07217405
- Testing
- Corticosteroid injection (CSI), Low-dose radiotherapy (LDRT)
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Mayo Clinic
Hand Osteoarthritis
Metformin Treatment of Patients with Hand Osteoarthritis
To compare metformin (2 g daily), or maximum tolerated dose, for 16 weeks with placebo as a treatment of hand osteoarthritis symptoms.
- Trial name
- METRO (NCT06367283)
- Testing
- Metformin
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Marius Henriksen
Osteoarthritis Hand
Efficacy of Surgical Joint Denervation in Painful Digital Osteoarthritis
Digital osteoarthritis is the second localization of symptomatic osteoarthritis, after the knee. Its cardinal symptoms are particularly intense pain and functional impairment in the case of the erosive form.
- Trial name
- DECAD (NCT05378841)
- Testing
- Surgical Denervation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hand Osteoarthritis, Erosive Osteoarthritis
A 30-month Follow-up of MERINO Participants to Evaluate Long-term Effects of Methotrexate in Erosive Hand OA.
In response to the high prevalence of synovitis in hand osteoarthritis (OA) and its association with pain, there\'s a compelling rationale for investigating the efficacy of MTX in managing inflammatory erosive hand OA.
- Trial name
- MERINO:2 (NCT06281184)
- Testing
- Methotrexate, Treatment as usual
- Where
- Norway
- Volunteers
- 108 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis Hand, Neuropathic Pain
Capsaicin in Digital Osteoarthritis Versus Control
The objective of this multicentric, randomized controlled double-blind clinical trial is to demonstrate the efficacy of transdermal application of capsaicin in patients with painful digital osteoarthritis with a neuropathic pain…
- Trial name
- CADOR (NCT06444919)
- Testing
- Capsaicin 179 Mg Cutaneous Patch, Capsaicine low dose 0.04 %
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoarthritis, Hand Osteoarthritis
Balneotherapy and Peloid Therapy Impact Small Joint Diseases
This clinical trial investigates the effects of natural healing factors (mineral water and mud procedures) in combination with regular rehabilitation of patients with degenerative small joint disease.
- Conditions
- Osteoarthritis, Hand Osteoarthritis, Foot Osteoarthritis
- Trial name
- NCT06477393
- Testing
- Regular rehababilitation, Heat procedures, Healing mud application
- Where
- 2 sites in Lithuania
- Volunteers
- 130 people
- Sponsor
- Lithuanian University of Health Sciences
Thumb Osteoarthritis
Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb
Thumb carpometacarpal (CMC) osteoarthritis (OA) is common, seen frequently in middle-aged and elderly women. While a variety of surgical treatments have been described with none superior to any other, there is no consensus on the…
- Trial name
- NCT04828954
- Testing
- Immobilization for 2-weeks postoperative, Immobilization for 6-weeks postoperative
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Chicago
Hand Osteoarthritis
The Efficacy and Safety of Intramuscular Methylprednisolone in Patients With Hand OsteoArthritis
The goal of this clinical trial is to determine the efficacy and safety of intramuscular methylprednisolone in patients with hand osteoarthritis.
- Trial name
- IMHOA (NCT07371572)
- Testing
- 120mg methylprednisolone acetate, 40mg methylprednisolone acetate
- Where
- Netherlands
- Volunteers
- 212 people
- Sponsor
- Sint Maartenskliniek
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Hand Osteoarthritis
An Integrated Self Management Programme to Improve Outcomes in Patients With Hand Osteoarthritis
The goal of this trial is to evaluate the efficacy of an integrated self-management programme in improving clinical outcomes in patients with hand osteoarthritis (OA).
- Trial name
- OASIS-H (NCT06264908)
- Testing
- Integrated self-management programme
- Volunteers
- 90 people
- Sponsor
- Dr Iris Tang Yan Ki
Osteoarthritis
Evaluation of the Safety of LipiodolⓇ Embolization in Symptomatic Digital Osteoarthritis Refractory to Conventional Treatment
The goal of this clinical trial is to evaluate the safety of arterial embolization using Lipiodol® in patients with symptomatic hand osteoarthritis refractory to conventional treatment.
- Trial name
- EMBARDI (NCT06611007)
- Testing
- embolization therapy
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Hand Osteoarthritis
A Prospective Cohort Study of Patients Suffering From Hand Osteoarthritis Symptoms
The late-stage forms of degenerative osteoarthritis (OA) are very debilitating and less affordable to therapy. The main objective is to identify early onset symptoms of hand OA patients through imaging techniques (such as…
- Trial name
- COARDIG (NCT03650673)
- Testing
- Identification of subgroups of patients with early AD with risk of progression
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Hand, Hand Therapy
Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System
This study investigates whether early changes observed during the first weeks of hand and upper extremity rehabilitation can predict patient outcomes months later.
- Conditions
- Hand, Hand Therapy, Upper Extremity, Prediction Models
- Trial name
- HANDREHPREDICT (NCT07522060)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Arthritis, Arthritis/Arthrosis
Combining Virtual Reality and Hypnosis to Alleviate Chronic Pain in Elderly Patients with Hand Arthritis
The goal of this pilot randomized clinical trial is to test the efficacy of an intervention combining virtual reality and hypnosis on decreasing pain and improving quality of life in elderly patients with hand arthritis.
- Conditions
- Arthritis, Arthritis/Arthrosis, Arthritis, Rheumatoid, Elderly
- Trial name
- VRHArthrisis (NCT06833905)
- Testing
- Virtual reality: Beach, Virtual Reality: Forest, Hypnosis: Magic Hand
- Volunteers
- 80 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Hand Osteoarthritis
Cross-sectorial Management Program for People Living with Hand Osteoarthritis: a Randomised Controlled Pilot and Feasibility Study
To investigate the research design (pilot-RCT) and feasibility of the HANDY program for people with hand osteoarthritis (version 2.0).
- Trial name
- HANDY (NCT06794632)
- Testing
- HANDY occupational therapy intervention
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Parker Research Institute
Hand Osteoarthritis
Testing of a New Joint Protection Program
The goal of this study is to to examine the feasibility of a full-scale trial on Helping Hand, a new Joint Protection Program for Hand Osteoarthritis and to examine the acceptability of the new Joint Protection Program.
- Trial name
- "Helping Hand" (NCT06963164)
- Testing
- Helping Hand - Joint Protection Program
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Thumb Osteoarthritis, Hand Osteoarthritis
Evaluation of the Effects of High Intensity Laser Therapy and Exercise in Hand Thumb Osteoarthritis
One of the standard treatment methods in individuals with thumb osteoarthritis (OA) is exercise. Combination therapy options involving these exercises can be applied to patients.
- Trial name
- NCT07112742
- Testing
- High-Intensity Laser Therapy and Exercise, High-Intensity Laser Therapy at a Non-Therapeutic Dose Combined With Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- TC Erciyes University
Osteoarthritis Hand
CapFlex PIP Implant RSA
Rationale: Patients with osteoarthrtis (OA) of the proximal interphalangeal (PIP) joint are commonly treated with joint arthroplasty.
- Trial name
- Capflex RSA (NCT05484089)
- Testing
- CapFlex PIP implant
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Erosive Hand Osteoarthritis
Methotrexate Treatment in Hand Osteoarthritis Refractory to Usual Treatments
Randomized study comparing the structural efficacy of methotrexate versus placebo in digital osteoarthritis
- Trial name
- ADEM2 (NCT07501507)
- Testing
- Methotrexate Injectable Solution
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Thumb Osteoarthritis, Hand Injuries
High-Energy Laser in the Conservative Treatment of Rhizarthrosis
Osteoarthritis (OA) is a degenerative joint disease that can affect the hands and is particularly debilitating when it involves the trapeziometacarpal joint (rhizarthrosis).
- Conditions
- Thumb Osteoarthritis, Hand Injuries, Laser, Exercise
- Trial name
- HLEX-TO (NCT07566507)
- Testing
- THEAL:Ixyon XP (Mectronic, Bergamo, Italy)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari