Clinical trials: Osteoarthritis Ankle
Investigate the Change in the Weight-bearing-line (WBL) Ratio of the Ankle Joint and Ankle Joint Line Orientation After HTO
Ankle Pain and Orientation After High Tibial Osteotomy as a Treatment of Medial Compartment Knee Osteoarthritis
Changes in demographics and physical activities of the young population have increased the number of patients with medial unicompartmental knee osteoarthritis (OA) requiring surgical intervention.
- Trial name
- NCT05183750
- Testing
- High tibial osteotomy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Ankle Sprain, Back Pain
Counterpain PXM Versus Diclofenac Versus Piroxicam
The goal of this clinical trial is to learn if a gel containing Piroxicam plus Counterirritant (warming/cooling ingredients) is as effective and safe as two other common anti-inflammatory gels for treating acute muscle, bone, and…
- Conditions
- Ankle Sprain, Back Pain, Osteoarthritis (OA) of the Knee, Tennis Elbow
- Trial name
- NCT07475663
- Testing
- Piroxicam plus Counterirritant (brand name Counterpain® PXM)., Diclofenac Sodium 10 mg (Brand Name Hotin® DCL), Piroxicam 0.5% (Brand name Pirofel® gel)
- Where
- Indonesia
- Volunteers
- 180 people
- Sponsor
- Taisho Pharmaceutical Indonesia
Arthrosis, Ankle Arthritis
Outcomes of Surgical Treatment Using a Custom-made Device for Total Ankle and Talar Replacement in the Management of Severe Cases of Bone Loss or Bone Compromise: a Pilot Study.
On February 17th, 2021, the FDA officially approved the use of the first patient-specific 3D-printed talar implant for compassionate use.
- Conditions
- Arthrosis, Ankle Arthritis, Ankle Replacement
- Trial name
- NCT07569848
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Istituto Ortopedico Rizzoli
Rheumatoid Arthritis of Ankle, Osteoarthritis of Ankle
Agility LP Ankle Arthroplasty Outcomes
This is a research study which is being done to determine the outcomes following Agility LP ankle replacement. This implant was approved by the FDA in 2007 and has been used since then with good early results.
- Conditions
- Rheumatoid Arthritis of Ankle, Osteoarthritis of Ankle, Traumatic Arthritis of Ankle
- Trial name
- NCT01366872
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Associates of Michigan, PC
Osteoarthritis
Joint Self-Assessment Forms for Knee, Ankle and Shoulder
The present study represents the pilot phase of the project aimed at developing anatomical site-specific self-assessment questionnaires (shoulder, knee and ankle) that can advise the subject of the need for an orthopaedic…
- Trial name
- NCT06343857
- Testing
- self-assessment questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Pain, Joint
Efficacy Evaluation of Hydrolyzed Collagen Peptide on Knees, Hips, and Ankle Pain in Osteoarthritis
The aim of this study is to evaluate the effectiveness of Hydrolyzed collagen peptides on joint pain, stiffness and physical function in adults with osteoarthritis who have complaints on knee joints together with hip and ankles.
- Trial name
- NCT05369780
- Testing
- Hydrolyzed Collagen Peptide
- Volunteers
- 160 people
- Sponsor
- Sel Sanayi Urunleri Ticaret ve Pazarlama A.S.
Ankle Osteoarthritis
Total Ankle Replacement for Ankle Arthritis
The purpose of this study is to prospectively evaluate the functional outcome and patient satisfaction of total ankle replacement for tibio-talar osteoarthritis.
- Trial name
- TAR1600 (NCT01986244)
- Where
- United States
- Volunteers
- 1,043 people
- Sponsor
- Duke University
Arthrodesis, Degenerative Arthritis
INBONE Total Ankle Arthroplasty(TAA)Using Calcaneal Stem Fixation
The primary objective of this study is to evaluate the radiographic outcomes of Total Ankle Arthroplasty in patients having a calcaneal stem.
- Conditions
- Arthrodesis, Degenerative Arthritis, Rheumatoid Arthritis, Complications; Arthroplasty, Mechanical
- Trial name
- NCT01366989
- Testing
- Radiographic evaluation of previously implanted patients
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stryker Trauma and Extremities
Knee Osteoarthritis
Strengthening Program for Foot-ankle Muscles in People With Knee Osteoarthritis
The main objective of this trial is To evaluate the effect of an ankle and foot muscle strengthening program on pain, analgesic consumption, functionality, and lower limb biomechanics during gait in individuals with knee…
- Trial name
- NCT04154059
- Testing
- Intervention Group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Sao Carlos
Ankle Osteoarthritis
Prospective Randomized Evaluation of a Two and Three Piece Total Ankle Replacement
This is a randomized study to prospectively compare and evaluate the functional outcome and patient satisfaction of total ankle replacements for tibio-talar osteoarthritis using either the STAR or Salto-Talaris prothesis.
- Trial name
- NCT01504438
- Testing
- Salto-Talaris Total Ankle Replacement, STAR Total Ankle Replacement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Duke University
Knee Osteoarthritis
Restoration of Physical Function in Patients Following Total Knee Replacement: Comparison Between Resistive Strength Training Exercises & Ankle Weights
Techniques used to restore the physical functions in TKR patients
- Trial name
- NCT05745649
- Testing
- Resistance exercises, Ankle weights
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Post Traumatic Arthritis, Osteoarthritis
A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System
The goal of this study is to demonstrate the safety and performance of the Incompass™ Total Ankle System after surgery over the standard follow-up period.
- Conditions
- Post Traumatic Arthritis, Osteoarthritis, Total Ankle Replacement, Total Ankle Prosthesis
- Trial name
- NCT07118501
- Testing
- Total Ankle Replacement
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stryker Trauma and Extremities
Ankle Osteoarthritis, Knee
Development of Stance Control Orthotic Knee Joint For Improvement of KAFO Users
I want to design Stance control orthotic knee joint for improvement of KAFO users which is not available in Pakistan imported stance control orthotic knee joints are very expensive patients can't afford.
- Trial name
- NCT06404801
- Testing
- Stance Control
- Where
- Pakistan
- Volunteers
- 2 people
- Sponsor
- Superior University
Rheumatoid Arthritis, Degenerative Arthritis
Clinical Evaluation of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement (CADENCE)
A post market, prospective, non-randomized, multi-center, open-label,clinical study using survivorship as the reference performance goal to study the safety and efficacy of the Cadence Total Ankle System (TAS) when used for…
- Conditions
- Rheumatoid Arthritis, Degenerative Arthritis, Post Traumatic Arthritis
- Trial name
- Cadence (NCT03142958)
- Testing
- Integra Cadence Total Ankle System
- Where
- 11 sites in United States, Canada
- Volunteers
- 132 people
- Sponsor
- Smith & Nephew, Inc.
Arthrosis, Unspecified, Ankle and Foot
Protracted Effect of the Ultrasound-guided Saphenous Block
This study focuses on optimizing the postoperative pain treatment after major foot and ankle surgery by prolonging the duration of the ultrasound-guided saphenous block.
- Trial name
- PEUSB (NCT02346110)
- Testing
- Bupivacaine-adrenaline, Dexamethasone, Sodium chloride
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1
A Proof of Science, Dose-Response Study to Evaluate the Safety, Efficacy of Different Dosages of Test Treatments
A proof of science clinical study with randomized, four-arm, comparative, single-blind, within the arm - Dose-Response Study to evaluate the safety and efficacy of different collagen peptide-containing test treatments in adult…
- Conditions
- Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1, Other Specified Diseases of Hair and Hair Follicles, Brittle Nails
- Trial name
- NCT05613660
- Testing
- Veg Collagen Peptide, Bovine Collagen Peptide, Fish | Marine Collagen Peptide
- Where
- India
- Volunteers
- 264 people
- Sponsor
- NovoBliss Research Pvt Ltd
Adult ALL, Healthy
Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics
The proposed study evaluates the effect of medial and lateral wedges and carbon fiber custom dynamic orthoses (CDOs) on lower limb forces and motion during walking.
- Trial name
- CDOKNEEpilot (NCT05209360)
- Testing
- Medial or Lateral Wedge, Carbon Fiber Custom Dynamic Orthosis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Osteoarthritis Ankle
MONOVISC for Ankle Joint Pain Relief Due to Osteoarthritis
The goal of this study is to demonstrate the clinical improvement and safety in patients treated with MONOVISC for ankle osteoarthritis.
- Trial name
- NCT04204278
- Testing
- Monovisc
- Where
- 4 sites in Czechia, Poland
- Volunteers
- 25 people
- Sponsor
- Anika Therapeutics, Inc.
Knee Osteoarthritis
Influence of Knee Alignment and Pelvis Rotation on Accuracy of Radiograph Measurements Before Total Knee Arthroplasty
The aim of this study is to determine the accuracy of long leg standing X-rays with respect to coronal alignment of the knee.
- Trial name
- NCT05277883
- Testing
- CT scan
- Where
- Slovenia
- Volunteers
- 112 people
- Sponsor
- Valdoltra Orthopedic Hospital
Ankle Osteoarthritis
Gait Analysis Following Total Ankle Replacement and Subtalar Fusion
Subtalar fusion is commonly performed in post-traumatic subtalar osteoarthritis, rheumatoid arthritis, posterior tibial tendon dysfunction, tarsal coalition and primary subtalar osteoarthritis.
- Trial name
- NCT03356951
- Testing
- TAR through anterior approach and subtalar fusion, TAR through lateral approach and subtalar fusion
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio