Clinical trials: Osteoarthritis, Hip
Osteoarthritis, Knee
The Influence of Hip Strengthening Exercises on Walking Patterns and Muscle Strength in Persons With Knee Osteoarthritis
The purpose of this study is to determine the influence of a home program of exercises for the hip muscles which support the pelvis on walking patterns and hip muscle strength in people with knee osteoarthritis.
- Trial name
- NCT00427843
- Testing
- home exercise program for the hip abductor muscles
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Queen's University
Hip Fracture, Osteoarthritis
Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery
The purpose of this study is to determine the effects of two postoperative interventions designed to preserve muscle protein after major hip or knee surgery.
- Conditions
- Hip Fracture, Osteoarthritis, Femur Head Necrosis
- Trial name
- NCT00393848
- Testing
- Essential amino acid supplement, Ketoconazole
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Arkansas
Osteoarthritis, Hip
Celecoxib Versus Diclofenac In The Treatment Of Osteoarthritis Of The Hip
To determine if celecoxib 200 mg once daily is as effective as diclofenac 50 mg three times daily in the treatment of pain symptoms associated with osteoarthritis of the hip
- Trial name
- NCT00174317
- Testing
- Celecoxib, Diclofenac
- Where
- 44 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- Pfizer
Total Hip Arthroplasty (THA), Hemiarthroplasty
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Primary Hip Prosthesis System
This is a multicenter, prospective, observational, post-market clinical follow-up (PMCF) study designed to evaluate the safety and clinical performance of the Tipmed™ Primary Hip Prosthesis System in adult subjects undergoing…
- Conditions
- Total Hip Arthroplasty (THA), Hemiarthroplasty, Osteoarthritis (OA) of the Hip, Femoral Neck Fractures
- Trial name
- NCT07651735
- Testing
- Tipmed™ Primary Hip Prosthesis System
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.
Osteoarthrosis
A Comparison of Two Total Hip Replacements: Hip Resurfacing System Versus Mallory-Head/Exeter
The purpose of this study is to compare two total hip replacement systems: Hip Resurfacing System (ReCap) versus Mallory-Head/Exeter.
- Trial name
- NCT00116948
- Testing
- ReCap, Hip resurfacing system, Biomet
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Necrosis of Femoral Head, Knee Osteoarthritis
Probiotics Attenuate Postoperative Cognition Decline
The aim of this study was to evaluate whether perioperative probiotics can reduce the incidence of postoperative cognitive dysfunction and postoperative delirium.
- Conditions
- Necrosis of Femoral Head, Knee Osteoarthritis, Fracture of Neck of Femur, Lumbar Disc Herniation
- Trial name
- NCT04017403
- Testing
- Bifidobacterium triple live capsule
- Where
- 3 sites in China
- Volunteers
- 220 people
- Sponsor
- RenJi Hospital
Primary Osteoarthritis, Secondary Osteoarthritis
Anthology Hip Replacement System - Orthopaedic Data Evolution Panel (ODEP) Surveillance Study
This clinical study will verify the clinical and radiographic performance of the prosthesis when used in human subjects over a period of 10 years. All complications will be documented.
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Avascular Necrosis, Primary Total Hip Replacement (THR)
- Trial name
- NCT04425603
- Testing
- Anthology Hip Replacement System
- Where
- 4 sites in United Kingdom
- Volunteers
- 270 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Avascular Necrosis of Femoral Head, Degenerative Arthritis of Hip
Rotational Thromboelastography Study in Tranexamic Acid and Colloid Infusion
Colloid solution is generally used to maintain intravascular volume. It is reported to impair blood coagulation in vivo and in vitro more than crystalloid does by prolonging coagulation time and decreasing clot strength.
- Trial name
- NCT02146456
- Testing
- Tranexamic Acid
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Bundang Hospital
Osteoarthritis
Blood Management in Orthopedic Surgery
Aim: to investigate whether the use of several transfusion alternatives (erythropoietin, the cell-saver or postoperative drainage and reinfusion systems) in patients undergoing elective total knee or hip replacement surgery can…
- Trial name
- TOMaat (NCT00998088)
- Testing
- erythropoietin and cell saver, erythropoietin, OrthoPAT
- Where
- 4 sites in Netherlands
- Volunteers
- 2,598 people
- Sponsor
- Sanquin Research & Blood Bank Divisions
Osteoarthritis
Gait Analysis of Anterior Versus Posterior Approach in Performance of Total Hip Arthroplasty
The primary objectives of the study is to compare gait kinematics and the return to normalization of gait in patients that have undergone a Total Hip Arthroplasty (THA) via the direct anterior approach versus the posterior…
- Trial name
- NCT00951951
- Testing
- Anterior Approach, Posterior Approach
- Where
- 4 sites in United States
- Volunteers
- 64 people
- Sponsor
- Medacta USA
Avascular Necrosis of Hip, Degenerative Hip Joint Disease
Revision Total Hip Replacement Arthroplasty and Hematologic Variables
Revision total hip replacement arthroplasty is a surgery having intra- and postoperative substantial blood loss. The investigators will investigate the relationship between the various hematologic variables and postoperative…
- Trial name
- NCT02951741
- Testing
- RTHRA group
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Seoul National University Bundang Hospital
Osteoarthritis, Hip, Blood Loss
Bipolar Sealer for Reduction of Blood Loss in Anterior Total Hip Arthroplasties
The overall objectives and purpose of this study is to show that the Smith and Nephew Werewolf Fastseal 6.0 Bipolar Sealer is an effective tool to aide the surgical team in providing significant hemostasis during anterior total…
- Trial name
- NCT05356637
- Testing
- Werewolf Fastseal 6.0
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- North Texas Medical Research Institute, PLLC
Osteoarthritis
RSA Study of Sirius Stem and Exceed Cup
The purpose of this study is to evaluate the efficacy and safety of the Sirius Cemented Stem used in conjunction with the Exceed ABT Cemented Acetabular Cup, either with E1 or Arcom polyethylene, and OptiPac/OptiVac bone cement…
- Trial name
- NCT02307331
- Testing
- Optivac, Optipac, Arcom (Exceed cup)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Region Skane
Hip Osteoarthritis
Time to Total Hip Replacement After Supervised Exercise and Patient Education
The purpose of this study is to evaluate the time to total hip replacement in patients with hip osteoarthritis going through both a supervised exercise program and patient education compared to patients going through patient…
- Trial name
- NCT01338532
- Testing
- A 12 week supervised exercise program and patient education, Patient education
- Where
- Norway
- Volunteers
- 109 people
- Sponsor
- Oslo University Hospital
Osteo Arthritis of the Knee
Comparison of the Effects of Two Different Exercise Programs on Femoral Cartilage Thickness and Clinical Parameters in Individuals With Knee Osteoarthritis
Knee osteoarthritis (OA) is one of the most common joint disorders worldwide and is a leading cause of pain, limited mobility, and functional disability, particularly in the elderly population.
- Trial name
- NCT07657481
- Testing
- Quadriceps Plus Hip Strengthening Exercises, Quadriceps Strengthening Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Pamukkale University
Osteoarthritis
A Qualitative Investigation of CLEAT Participants
As the United Kingdom's National Health Service (NHS) waiting list soars above seven million people, with treatment wait times over two years, older people with chronic conditions face worsening symptoms, increased use of…
- Trial name
- NCT05937542
- Testing
- Qualitative Investigation of Participant Experiences
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Osteoarthritis, Femoral Head Necrosis
Donepezil Attenuate Postoperative Cognitive Dysfunction
Postoperative cognitive dysfunction (POCD) occurs mainly in aged patients. POCD may increase the mortality and morbidity. However, the mechanism of POCD is not clear yet and no effective therapy method was proved.
- Conditions
- Osteoarthritis, Femoral Head Necrosis, Rheumatoid Arthritis
- Trial name
- DAPOCD (NCT02927522)
- Testing
- Donepezil
- Where
- China
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Chronic Osteoarthritis
OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects
The primary objectives are to demonstrate that the treatment with OXN PR tablets is non-inferior to the treatment with OxyPR with regards to analgesic efficacy and locomotor function.
- Trial name
- NCT00902837
- Testing
- Oxycodone naloxone prolonged release tablets (OXN), oxycodone prolonged release tablet, oxycodone naloxone tablet
- Where
- 36 sites in Belgium, Czechia and 4 more
- Volunteers
- 181 people
- Sponsor
- Mundipharma Research GmbH & Co KG
Hip Osteoarthritis, Knee Osteoarthritis
Backwards Walking Programme Following Hip and Knee Arthroplasty
Backwards walking has been shown to improve balance and walking in patients who have knee Osteoarthritis. It is not known if these benefits may also be seen after surgery in patients who have had a hip or knee replacement because…
- Conditions
- Hip Osteoarthritis, Knee Osteoarthritis, Hip Arthroplasty, Knee Arthroplasty
- Trial name
- NCT04247802
- Testing
- Backwards Walking (BW) programme, Usual Care
- Where
- 2 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- Oxford University Hospitals NHS Trust
Joint Disease
Post Market Clinical Follow-Up Study Protocol for PROCOTYL® C Acetabular Components
MicroPort Orthopedics (MPO) is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) components marketed in the European Union (EU).
- Trial name
- NCT03576573
- Testing
- PROCOTYL® C
- Where
- Germany
- Volunteers
- 143 people
- Sponsor
- MicroPort Orthopedics Inc.
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